SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ctm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		4 / 7 THR A 264
PHE A  75
SER A 196
LEU A 236
 None
 1.07A 1qcaA-5ctmA:
undetectable		 1qcaA-5ctmA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
GLY A 241
SER A 242
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.2A)
FLC  A 301 (-2.8A)
None
 0.74A 1ymxB-5ctmA:
18.8		 1ymxB-5ctmA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 ALA A 106
ILE A 195
ILE A 180
ALA A 172
ILE A 173
 None
 0.92A 2b60A-5ctmA:
undetectable		 2b60A-5ctmA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 11 ILE A 246
GLU A  95
GLY A  73
THR A  74
GLY A 247
 None
 1.19A 2fn1A-5ctmA:
undetectable		 2fn1A-5ctmA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 11 ILE A 246
GLU A  95
GLY A  73
THR A  74
GLY A 247
 None
 1.14A 2fn1B-5ctmA:
undetectable		 2fn1B-5ctmA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 109
MET A 157
MET A 146
THR A 114
MET A 166
 None
None
KCX  A 104 ( 4.6A)
None
None
 1.13A 2q7iA-5ctmA:
undetectable		 2q7iA-5ctmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 109
MET A 157
MET A 146
THR A 114
MET A 166
 None
None
KCX  A 104 ( 4.6A)
None
None
 1.13A 2q7kA-5ctmA:
undetectable		 2q7kA-5ctmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 181
GLN A 200
THR A 102
ASN A 177
PHE A 103
 None
 1.28A 2vdyA-5ctmA:
undetectable		 2vdyA-5ctmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 181
GLN A 200
THR A 102
ASN A 177
PHE A 103
 None
 1.29A 2vdyB-5ctmA:
undetectable		 2vdyB-5ctmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 109
MET A 157
MET A 146
THR A 114
MET A 166
 None
None
KCX  A 104 ( 4.6A)
None
None
 1.19A 2yloA-5ctmA:
undetectable		 2yloA-5ctmA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 10 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.00A 3ekpC-5ctmA:
undetectable		 3ekpC-5ctmA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 11 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.05A 3ektD-5ctmA:
undetectable		 3ektD-5ctmA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 10 ALA A 106
ILE A 195
ILE A 180
ALA A 172
ILE A 173
 None
 0.92A 3ekwA-5ctmA:
undetectable		 3ekwA-5ctmA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 9 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.00A 3el0B-5ctmA:
undetectable		 3el0B-5ctmA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 10 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.02A 3el5A-5ctmA:
undetectable		 3el5A-5ctmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 149
LYS A 239
THR A 240
GLY A 241
SER A 242
GLY A 243
 FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
FLC  A 301 (-2.8A)
None
 0.69A 3hlwB-5ctmA:
18.9		 3hlwB-5ctmA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.06A 3mwsA-5ctmA:
undetectable		 3mwsA-5ctmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.01A 3mwsB-5ctmA:
undetectable		 3mwsB-5ctmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.45A 3ny4A-5ctmA:
17.9		 3ny4A-5ctmA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 149
LYS A 239
GLY A 241
SER A 242
GLY A 243
 FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.2A)
FLC  A 301 (-2.8A)
None
 0.63A 3q07B-5ctmA:
18.6		 3q07B-5ctmA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.05A 3spkB-5ctmA:
undetectable		 3spkB-5ctmA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 109
MET A 157
MET A 146
THR A 114
MET A 166
 None
None
KCX  A 104 ( 4.6A)
None
None
 1.14A 3zqtA-5ctmA:
undetectable		 3zqtA-5ctmA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 181
GLN A 200
THR A 102
ASN A 177
PHE A 103
 None
 1.36A 4c49B-5ctmA:
undetectable		 4c49B-5ctmA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 181
GLN A 200
THR A 102
ASN A 177
PHE A 103
 None
 1.33A 4c49C-5ctmA:
undetectable		 4c49C-5ctmA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 181
GLN A 200
THR A 102
ASN A 177
PHE A 103
 None
 1.27A 4c49D-5ctmA:
undetectable		 4c49D-5ctmA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 109
MET A 157
MET A 146
THR A 114
MET A 166
 None
None
KCX  A 104 ( 4.6A)
None
None
 1.17A 4hlwA-5ctmA:
undetectable		 4hlwA-5ctmA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.05A 4njuA-5ctmA:
undetectable		 4njuA-5ctmA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.04A 4njuC-5ctmA:
undetectable		 4njuC-5ctmA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 149
LYS A 239
THR A 240
GLY A 241
SER A 242
GLY A 243
 FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
FLC  A 301 (-2.8A)
None
 0.59A 4pm5A-5ctmA:
18.7		 4pm5A-5ctmA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.37A 4pm9A-5ctmA:
18.9		 4pm9A-5ctmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 9 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.10A 5kqxB-5ctmA:
undetectable		 5kqxB-5ctmA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		4 / 8 TYR A 249
ILE A 253
THR A 277
ILE A 280
 None
 0.88A 5mzrE-5ctmA:
undetectable		 5mzrE-5ctmA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 LEU A 262
VAL A  87
GLY A  73
ILE A 266
PRO A 197
 None
 1.08A 5t2zA-5ctmA:
undetectable		 5t2zA-5ctmA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.66A 6b5yB-5ctmA:
18.0		 6b5yB-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.71A 6b5yD-5ctmA:
18.0		 6b5yD-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.55A 6b68B-5ctmA:
18.0		 6b68B-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 101
SER A 149
LYS A 239
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.2A)
None
 0.61A 6b68D-5ctmA:
17.4		 6b68D-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.60A 6b69A-5ctmA:
17.9
6b69B-5ctmA:
17.3		 6b69A-5ctmA:
13.45
6b69B-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.61A 6b69D-5ctmA:
17.9		 6b69D-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.59A 6b6aB-5ctmA:
18.0		 6b6aB-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.59A 6b6aD-5ctmA:
17.8		 6b6aD-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.69A 6b6cA-5ctmA:
17.8		 6b6cA-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.46A 6b6dA-5ctmA:
17.7		 6b6dA-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		6 / 12 SER A 101
SER A 149
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.67A 6b6eA-5ctmA:
18.0		 6b6eA-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 101
LYS A 239
THR A 240
GLY A 241
GLY A 243
 KCX  A 104 (-2.2A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.8A)
FLC  A 301 (-3.2A)
None
 0.43A 6b6fA-5ctmA:
17.6		 6b6fA-5ctmA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		5 / 12 SER A 149
LYS A 239
GLY A 241
SER A 242
GLY A 243
 FLC  A 301 (-2.5A)
FLC  A 301 (-3.0A)
FLC  A 301 (-3.2A)
FLC  A 301 (-2.8A)
None
 0.67A 6c79A-5ctmA:
18.9		 6c79A-5ctmA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 5ctm BETA-LACTAMASE
(Bacillus
pumilus) 		4 / 7 GLN A 228
GLY A 238
PHE A 252
VAL A 201
 None
 1.02A 6hu9S-5ctmA:
undetectable
6hu9q-5ctmA:
undetectable		 6hu9S-5ctmA:
14.61
6hu9q-5ctmA:
17.84