SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cuw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 5cuw SRTE1
(Streptomyces
coelicolor) 		5 / 11 ALA A 237
GLY A 247
ILE A 315
PRO A 303
VAL A 302
 None
 1.07A 2o4pA-5cuwA:
undetectable		 2o4pA-5cuwA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 5cuw SRTE1
(Streptomyces
coelicolor) 		4 / 5 HIS A 201
VAL A 272
GLU A 274
VAL A 208
 None
 1.47A 4p6vB-5cuwA:
undetectable
4p6vE-5cuwA:
undetectable		 4p6vB-5cuwA:
18.36
4p6vE-5cuwA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5cuw SRTE1
(Streptomyces
coelicolor) 		5 / 11 GLY A 247
ILE A 315
GLY A 250
ILE A 211
PHE A 197
 None
 1.13A 4qoiA-5cuwA:
undetectable
4qoiB-5cuwA:
undetectable		 4qoiA-5cuwA:
19.66
4qoiB-5cuwA:
19.66