SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cuz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5cuz METHYLMALONIC
ACIDURIA AND
HOMOCYSTINURIA TYPE
D PROTEIN,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 TYR A 249
LEU A 252
ALA A 208
PHE A 224
VAL A 276
 None
 1.44A 2g70B-5cuzA:
undetectable		 2g70B-5cuzA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5cuz METHYLMALONIC
ACIDURIA AND
HOMOCYSTINURIA TYPE
D PROTEIN,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 THR A 152
GLN A 151
THR A 177
VAL A 178
VAL A 276
 None
 1.26A 6bzoC-5cuzA:
undetectable		 6bzoC-5cuzA:
10.76