SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		4 / 7 ASN A 354
ALA A 428
ALA A 432
GLN A 358
 None
 0.82A 3a2qA-5cv1A:
undetectable		 3a2qA-5cv1A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		4 / 7 ASN A 354
ALA A 428
ALA A 432
GLN A 358
 None
 0.88A 3a2qA-5cv1A:
undetectable		 3a2qA-5cv1A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		5 / 12 ALA A 432
LEU A 314
GLN A 358
SER A 398
ILE A 399
 None
 1.42A 3ia4A-5cv1A:
undetectable		 3ia4A-5cv1A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		4 / 4 LEU A 352
LEU A 391
GLN A 358
GLU A 320
 None
 1.24A 4i41A-5cv1A:
undetectable		 4i41A-5cv1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		3 / 3 SER A 263
MET A 266
ASP A 405
 None
 0.88A 4mm4B-5cv1A:
undetectable		 4mm4B-5cv1A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		4 / 5 LEU A 454
SER A 456
LEU A 360
ASN A 424
 None
 1.23A 4n09C-5cv1A:
undetectable		 4n09C-5cv1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		5 / 12 PHE A 469
GLY A 353
LEU A 352
VAL A 375
VAL A 479
 None
 0.94A 4wnwB-5cv1A:
undetectable		 4wnwB-5cv1A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5cv1 P GRANULE
ABNORMALITY PROTEIN
1
(Caenorhabditis
elegans) 		5 / 12 ILE A 482
LEU A 461
PHE A 466
SER A 465
THR A 436
 None
 1.11A 6b52A-5cv1A:
undetectable		 6b52A-5cv1A:
24.04