SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 11 SER A 164
ASN A 163
GLY A 194
GLY A 200
GLN A 171
 None
None
PLP  A 402 (-3.5A)
None
None
 1.08A 1jr1A-5cvcA:
undetectable		 1jr1A-5cvcA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 10 SER A 164
ASN A 163
ILE A 162
GLY A 194
GLY A 200
 None
None
PLP  A 402 ( 4.8A)
PLP  A 402 (-3.5A)
None
 1.06A 1mehA-5cvcA:
undetectable		 1mehA-5cvcA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 12 SER A 322
GLU A  58
ARG A  69
ALA A 205
ILE A 188
 PLP  A 402 (-2.6A)
None
None
None
None
 1.11A 1s14B-5cvcA:
undetectable		 1s14B-5cvcA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 12 GLU A 290
GLY A 293
CYH A 281
ALA A 294
ALA A 277
 PLP  A 402 (-3.5A)
PLP  A 402 ( 4.7A)
None
None
None
 1.12A 2br4B-5cvcA:
3.3		 2br4B-5cvcA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 11 LEU A 285
VAL A 289
ILE A  45
ALA A 294
LEU A 301
 None
 0.87A 2q72A-5cvcA:
undetectable		 2q72A-5cvcA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 12 LEU A 285
VAL A 289
ILE A  45
ALA A 294
LEU A 301
 None
 0.92A 2qb4A-5cvcA:
undetectable		 2qb4A-5cvcA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 12 ILE A 133
GLY A 131
ALA A 103
ALA A  97
VAL A 126
 None
 1.10A 3jb3A-5cvcA:
undetectable		 3jb3A-5cvcA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5cvc SERINE RACEMASE
(Zea
mays) 		3 / 3 PRO A 119
SER A  92
ASN A 117
 None
 0.90A 3lslG-5cvcA:
undetectable		 3lslG-5cvcA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 11 VAL A 201
ILE A 320
GLY A 296
VAL A 263
ILE A 198
 None
 1.00A 3lzvB-5cvcA:
undetectable		 3lzvB-5cvcA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 10 VAL A 201
ILE A 320
GLY A 296
VAL A 263
ILE A 198
 None
 0.93A 3nu6A-5cvcA:
undetectable		 3nu6A-5cvcA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 10 VAL A 201
ILE A 320
GLY A 296
VAL A 263
ILE A 198
 None
 1.00A 3nujA-5cvcA:
undetectable		 3nujA-5cvcA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5cvc SERINE RACEMASE
(Zea
mays) 		4 / 8 ALA A  71
GLY A  70
THR A 167
GLN A 171
 None
 0.93A 3rglA-5cvcA:
undetectable		 3rglA-5cvcA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5cvc SERINE RACEMASE
(Zea
mays) 		4 / 5 ILE A 162
ALA A 249
HIS A  95
ARG A 143
 PLP  A 402 ( 4.8A)
None
None
None
 1.28A 4ac9B-5cvcA:
2.6
4ac9C-5cvcA:
3.9		 4ac9B-5cvcA:
20.99
4ac9C-5cvcA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		4 / 8 SER A 164
ASN A 163
GLY A 200
GLN A 171
 None
 0.69A 4af0A-5cvcA:
undetectable		 4af0A-5cvcA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		4 / 8 SER A 164
ASN A 163
GLY A 194
GLY A 200
 None
None
PLP  A 402 (-3.5A)
None
 0.61A 4fo4B-5cvcA:
undetectable		 4fo4B-5cvcA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 11 ILE A 267
PHE A  55
ILE A 189
ALA A 277
VAL A 269
 None
 1.16A 4h1nA-5cvcA:
undetectable		 4h1nA-5cvcA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 12 GLY A 172
ALA A  26
ALA A  31
LEU A 178
ALA A 205
 None
 0.82A 5bw4B-5cvcA:
undetectable		 5bw4B-5cvcA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5cvc SERINE RACEMASE
(Zea
mays) 		5 / 12 ILE A 243
ILE A 295
VAL A 268
ASP A 270
ILE A 274
 None
 1.02A 6emuC-5cvcA:
undetectable		 6emuC-5cvcA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5cvc SERINE RACEMASE
(Zea
mays) 		4 / 7 ARG A  24
ALA A  26
ILE A  20
ALA A 204
 None
 0.95A 6ma7A-5cvcA:
undetectable		 6ma7A-5cvcA:
14.04