SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 11 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.95A 1c6yA-5cw5A:
undetectable		 1c6yA-5cw5A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.94A 1hpvA-5cw5A:
undetectable		 1hpvA-5cw5A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.91A 1hxbB-5cw5A:
undetectable		 1hxbB-5cw5A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.94A 1ohrB-5cw5A:
undetectable		 1ohrB-5cw5A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		4 / 5 ARG A 171
MET A 173
THR A 174
LEU A 222
 None
 1.22A 2eimJ-5cw5A:
undetectable		 2eimJ-5cw5A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		4 / 5 ARG A 171
MET A 173
THR A 174
LEU A 222
 None
 1.25A 2eimW-5cw5A:
undetectable		 2eimW-5cw5A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.94A 2f80B-5cw5A:
undetectable		 2f80B-5cw5A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 1.01A 2o4pB-5cw5A:
undetectable		 2o4pB-5cw5A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.95A 3d20B-5cw5A:
undetectable		 3d20B-5cw5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 10 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.97A 3ekpB-5cw5A:
undetectable		 3ekpB-5cw5A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 10 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.96A 3ekpC-5cw5A:
undetectable		 3ekpC-5cw5A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.99A 3ekqB-5cw5A:
undetectable		 3ekqB-5cw5A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 ARG A 168
ALA A  72
GLY A  91
LEU A  90
ILE A  50
 None
 1.09A 3em4B-5cw5A:
undetectable		 3em4B-5cw5A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.92A 3k4vC-5cw5A:
undetectable		 3k4vC-5cw5A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.96A 3lzsA-5cw5A:
undetectable		 3lzsA-5cw5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.98A 3lzsB-5cw5A:
undetectable		 3lzsB-5cw5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.97A 3lzuA-5cw5A:
undetectable		 3lzuA-5cw5A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.91A 3ndtD-5cw5A:
undetectable		 3ndtD-5cw5A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.93A 3nduC-5cw5A:
undetectable		 3nduC-5cw5A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.92A 3nujB-5cw5A:
undetectable		 3nujB-5cw5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.95A 3nuoB-5cw5A:
undetectable		 3nuoB-5cw5A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.95A 3pwmB-5cw5A:
undetectable		 3pwmB-5cw5A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.98A 3tkgD-5cw5A:
undetectable		 3tkgD-5cw5A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.99A 3tkwA-5cw5A:
undetectable		 3tkwA-5cw5A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		4 / 7 THR A 172
HIS A  22
TYR A  93
LEU A  52
 None
 1.30A 4awuA-5cw5A:
undetectable		 4awuA-5cw5A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 11 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.99A 4njtA-5cw5A:
undetectable		 4njtA-5cw5A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 10 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 1.01A 4njuB-5cw5A:
undetectable		 4njuB-5cw5A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 10 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 1.00A 4njuD-5cw5A:
undetectable		 4njuD-5cw5A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.91A 4rvjB-5cw5A:
undetectable		 4rvjB-5cw5A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.92A 4rvjD-5cw5A:
undetectable		 4rvjD-5cw5A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		3 / 3 GLN A  12
THR A 162
ASP A  14
 None
 0.92A 5k9dA-5cw5A:
undetectable		 5k9dA-5cw5A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 9 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.87A 5kqxB-5cw5A:
undetectable		 5kqxB-5cw5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		4 / 5 ARG A 171
MET A 173
THR A 174
LEU A 222
 None
 1.27A 5w97J-5cw5A:
undetectable		 5w97J-5cw5A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.93A 6dgxA-5cw5A:
undetectable		 6dgxA-5cw5A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 5cw5 BRCA1/BRCA2-CONTAINI
NG COMPLEX SUBUNIT 3
(Camponotus
floridanus) 		5 / 12 LEU A  79
VAL A  89
GLY A  33
ILE A  51
ILE A  36
 None
 0.93A 6dh3A-5cw5A:
undetectable		 6dh3A-5cw5A:
13.41