SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cw6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5cw6 DRBRCC36
(Danio
rerio) 		4 / 7 LEU A   8
SER A  10
PHE A  13
LEU A  14
 None
 0.71A 1j8uA-5cw6A:
undetectable		 1j8uA-5cw6A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5cw6 DRBRCC36
(Danio
rerio) 		4 / 8 ILE A 161
LEU A  31
VAL A  15
ILE A  49
 None
 0.80A 4r38A-5cw6A:
undetectable		 4r38A-5cw6A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 5cw6 DRBRCC36
(Danio
rerio) 		4 / 5 ASP A  37
VAL A  88
ASP A 116
GLY A 118
 None
 1.21A 4xp6A-5cw6A:
undetectable		 4xp6A-5cw6A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 5cw6 DRBRCC36
(Danio
rerio) 		4 / 5 THR A 141
HIS A  92
ASP A 105
HIS A  94
 None
ZN  A1001 (-3.5A)
ZN  A1001 (-2.2A)
ZN  A1001 (-3.3A)
 1.42A 6dchA-5cw6A:
undetectable		 6dchA-5cw6A:
24.63