SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cwd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 5cwd DESIGNED HELICAL
REPEAT PROTEIN
(synthetic
construct) 		4 / 6 PHE A  52
GLU A  78
LEU A  77
VAL A 121
 None
 1.01A 1hk1A-5cwdA:
undetectable		 1hk1A-5cwdA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5cwd DESIGNED HELICAL
REPEAT PROTEIN
(synthetic
construct) 		4 / 4 ALA A  56
ALA A  59
ALA A  72
ALA A  75
 None
 0.57A 6gtqA-5cwdA:
0.0
6gtqB-5cwdA:
0.0		 6gtqA-5cwdA:
20.83
6gtqB-5cwdA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5cwd DESIGNED HELICAL
REPEAT PROTEIN
(synthetic
construct) 		4 / 4 ALA A  72
ALA A  75
ALA A  56
ALA A  59
 None
 0.58A 6gtqA-5cwdA:
0.0
6gtqB-5cwdA:
0.0		 6gtqA-5cwdA:
20.83
6gtqB-5cwdA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5cwd DESIGNED HELICAL
REPEAT PROTEIN
(synthetic
construct) 		4 / 4 ALA A  98
ALA A 101
ALA A 114
ALA A 117
 None
 0.71A 6gtqA-5cwdA:
0.0
6gtqB-5cwdA:
0.0		 6gtqA-5cwdA:
20.83
6gtqB-5cwdA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5cwd DESIGNED HELICAL
REPEAT PROTEIN
(synthetic
construct) 		4 / 4 ALA A 114
ALA A 117
ALA A  98
ALA A 101
 None
 0.71A 6gtqA-5cwdA:
0.0
6gtqB-5cwdA:
0.0		 6gtqA-5cwdA:
20.83
6gtqB-5cwdA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5cwd DESIGNED HELICAL
REPEAT PROTEIN
(synthetic
construct) 		4 / 4 ALA A 140
ALA A 143
ALA A 156
ALA A 159
 None
 0.74A 6gtqA-5cwdA:
0.0
6gtqB-5cwdA:
0.0		 6gtqA-5cwdA:
20.83
6gtqB-5cwdA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5cwd DESIGNED HELICAL
REPEAT PROTEIN
(synthetic
construct) 		4 / 4 ALA A 156
ALA A 159
ALA A 140
ALA A 143
 None
 0.75A 6gtqA-5cwdA:
0.0
6gtqB-5cwdA:
0.0		 6gtqA-5cwdA:
20.83
6gtqB-5cwdA:
20.83