SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cwj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	5cwj	DESIGNED HELICAL REPEAT PROTEIN (synthetic construct)	3 / 3	SER A 62 GLU A 63 GLU A 64	None	0.67A	1eqbD-5cwjA: undetectable	1eqbD-5cwjA: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5cwj	DESIGNED HELICAL REPEAT PROTEIN (synthetic construct)	3 / 3	SER A 62 GLU A 63 GLU A 64	None	0.66A	1eqbB-5cwjA: undetectable	1eqbB-5cwjA: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KI7_B_ID2B2_0 (THYMIDINE KINASE)	5cwj	DESIGNED HELICAL REPEAT PROTEIN (synthetic construct)	5 / 12	ILE A 90 ILE A 116 ALA A 80 ARG A 91 GLU A 128	None	1.49A	1ki7B-5cwjA: 3.3	1ki7B-5cwjA: 18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G24_A_ACAA1004_1 (PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN AT2G32230, MITOCHONDRIAL)	5cwj	DESIGNED HELICAL REPEAT PROTEIN (synthetic construct)	4 / 6	ALA A 17 LEU A 26 ASP A 32 GLU A 31	None	1.07A	4g24A-5cwjA: 6.8	4g24A-5cwjA: 15.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQB_A_FFOA1293_2","SERINE HYDROXYMETHYLTRANSFERASE","5cwj","DESIGNED HELICAL REPEAT PROTEIN","synthetic construct",3,"SER A  62;GLU A  63;GLU A  64","None","0.67A","1eqbD-5cwjA:undetectable","1eqbD-5cwjA:17.54"],["1EQB_C_FFOC3293_0","SERINE HYDROXYMETHYLTRANSFERASE","5cwj","DESIGNED HELICAL REPEAT PROTEIN","synthetic construct",3,"SER A  62;GLU A  63;GLU A  64","None","0.66A","1eqbB-5cwjA:undetectable","1eqbB-5cwjA:17.54"],["1KI7_B_ID2B2_0","THYMIDINE KINASE","5cwj","DESIGNED HELICAL REPEAT PROTEIN","synthetic construct",5,"ILE A  90;ILE A 116;ALA A  80;ARG A  91;GLU A 128","None","1.49A","1ki7B-5cwjA:3.3","1ki7B-5cwjA:18.07"],["4G24_A_ACAA1004_1","PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN AT2G32230, MITOCHONDRIAL","5cwj","DESIGNED HELICAL REPEAT PROTEIN","synthetic construct",4,"ALA A  17;LEU A  26;ASP A  32;GLU A  31","None","1.07A","4g24A-5cwjA:6.8","4g24A-5cwjA:15.61"]]