SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cx0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 117
GLY A  46
GLY A  44
ALA A  42
VAL A 139
 None
56L  A 205 (-3.7A)
None
None
None
 1.05A 2zulA-5cx0A:
undetectable		 2zulA-5cx0A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 117
GLY A  46
GLY A  44
ALA A  42
VAL A 139
 None
56L  A 205 (-3.7A)
None
None
None
 1.08A 3dmfA-5cx0A:
undetectable		 3dmfA-5cx0A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 117
GLY A  46
GLY A  44
ALA A  42
VAL A 139
 None
56L  A 205 (-3.7A)
None
None
None
 1.08A 3dmhA-5cx0A:
undetectable		 3dmhA-5cx0A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		4 / 8 ARG A 129
ALA A  79
ASP A 123
SER A 125
 None
 0.94A 3qj7A-5cx0A:
undetectable
3qj7D-5cx0A:
undetectable		 3qj7A-5cx0A:
20.54
3qj7D-5cx0A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 PRO A 152
GLY A 162
PHE A 161
GLY A  98
TYR A 151
 None
None
None
56L  A 205 (-3.5A)
None
 1.18A 4lxzA-5cx0A:
undetectable		 4lxzA-5cx0A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 12 PRO A 152
GLY A 162
PHE A 161
GLY A  98
TYR A 151
 None
None
None
56L  A 205 (-3.5A)
None
 1.16A 4lxzC-5cx0A:
undetectable		 4lxzC-5cx0A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 10 ALA A  79
THR A  78
ALA A  83
GLY A 119
ASP A 123
 None
 1.17A 5lf3H-5cx0A:
undetectable
5lf3I-5cx0A:
undetectable		 5lf3H-5cx0A:
20.92
5lf3I-5cx0A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		5 / 10 ALA A  79
THR A  78
ALA A  83
GLY A 119
ASP A 123
 None
 1.18A 5lf3V-5cx0A:
undetectable
5lf3W-5cx0A:
undetectable		 5lf3V-5cx0A:
20.92
5lf3W-5cx0A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		3 / 3 GLU A 142
HIS A 141
ARG A 137
 56L  A 205 (-3.3A)
CD  A 201 ( 3.5A)
None
 0.94A 5uunA-5cx0A:
undetectable		 5uunA-5cx0A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5cx0 PEPTIDE DEFORMYLASE
(Xanthomonas
oryzae) 		3 / 3 HIS A 145
HIS A 141
ARG A 111
 CD  A 201 (-3.5A)
CD  A 201 ( 3.5A)
None
 1.12A 6b58A-5cx0A:
undetectable		 6b58A-5cx0A:
15.05