SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cx7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLN A 135
GLY A 107
GLY A 119
THR A  77
ALA A  76
 None
None
None
None
GOL  A 204 ( 4.0A)
 1.15A 1jg2A-5cx7A:
undetectable		 1jg2A-5cx7A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 ILE A 141
VAL A 143
ARG A 112
 None
 0.64A 3p73A-5cx7A:
undetectable		 3p73A-5cx7A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A  20
VAL A  37
GLY A 125
ASP A 130
MET A  52
 None
None
GOL  A 202 (-4.2A)
GOL  A 202 (-3.6A)
None
 1.41A 4mubA-5cx7A:
undetectable		 4mubA-5cx7A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		4 / 8 GLY A  44
GLY A 119
ILE A  39
LEU A 110
 None
 0.72A 4mwzB-5cx7A:
undetectable		 4mwzB-5cx7A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		4 / 8 LEU A  20
VAL A  48
VAL A  37
LEU A  12
 None
 1.01A 4pwdC-5cx7A:
undetectable		 4pwdC-5cx7A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A 110
GLU A 128
GLY A 107
ALA A  67
ILE A  39
 None
 1.16A 4xe5A-5cx7A:
undetectable		 4xe5A-5cx7A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 THR A  75
GLY A 118
ILE A 115
ALA A  11
ALA A  42
 None
 1.15A 5kvaA-5cx7A:
undetectable		 5kvaA-5cx7A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 THR A  75
GLY A 118
ILE A 115
ALA A  11
ALA A  42
 None
 1.18A 5kvaB-5cx7A:
undetectable		 5kvaB-5cx7A:
18.87