SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cxm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5cxm	CYTOCHROME B6/F COMPLEX IRON-SULFUR SUBUNIT (Synechocystis sp. PCC 6803)	4 / 5	PRO A 75 GLY A 57 ASN A 53 GLY A 52	None	1.13A	1zlqA-5cxmA: undetectable	1zlqA-5cxmA: 12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KMO_A_EAAA214_1 (GLUTATHIONE S-TRANSFERASE P)	5cxm	CYTOCHROME B6/F COMPLEX IRON-SULFUR SUBUNIT (Synechocystis sp. PCC 6803)	5 / 9	TYR A 120 VAL A 59 GLY A 57 ASN A 53 GLY A 52	None	1.36A	3kmoA-5cxmA: undetectable	3kmoA-5cxmA: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_A_ACTA500_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	5cxm	CYTOCHROME B6/F COMPLEX IRON-SULFUR SUBUNIT (Synechocystis sp. PCC 6803)	4 / 4	ALA A 113 HIS A 79 HIS A 98 PRO A 112	None FES A 201 ( 3.1A) NI A 203 ( 3.2A) FES A 201 (-4.2A)	1.20A	3mbgA-5cxmA: undetectable	3mbgA-5cxmA: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_C_ACTC900_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	5cxm	CYTOCHROME B6/F COMPLEX IRON-SULFUR SUBUNIT (Synechocystis sp. PCC 6803)	4 / 4	ALA A 113 HIS A 79 HIS A 98 PRO A 112	None FES A 201 ( 3.1A) NI A 203 ( 3.2A) FES A 201 (-4.2A)	1.20A	3mbgC-5cxmA: undetectable	3mbgC-5cxmA: 20.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZLQ_A_ACTA1502_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5cxm","CYTOCHROME B6\/F COMPLEX IRON-SULFUR SUBUNIT","Synechocystis sp. PCC 6803",4,"PRO A  75;GLY A  57;ASN A  53;GLY A  52","None","1.13A","1zlqA-5cxmA:undetectable","1zlqA-5cxmA:12.15"],["3KMO_A_EAAA214_1","GLUTATHIONE S-TRANSFERASE P","5cxm","CYTOCHROME B6\/F COMPLEX IRON-SULFUR SUBUNIT","Synechocystis sp. PCC 6803",5,"TYR A 120;VAL A  59;GLY A  57;ASN A  53;GLY A  52","None","1.36A","3kmoA-5cxmA:undetectable","3kmoA-5cxmA:22.66"],["3MBG_A_ACTA500_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","5cxm","CYTOCHROME B6\/F COMPLEX IRON-SULFUR SUBUNIT","Synechocystis sp. PCC 6803",4,"ALA A 113;HIS A  79;HIS A  98;PRO A 112","None;FES A 201 ( 3.1A); NI A 203 ( 3.2A);FES A 201 (-4.2A)","1.20A","3mbgA-5cxmA:undetectable","3mbgA-5cxmA:20.31"],["3MBG_C_ACTC900_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","5cxm","CYTOCHROME B6\/F COMPLEX IRON-SULFUR SUBUNIT","Synechocystis sp. PCC 6803",4,"ALA A 113;HIS A  79;HIS A  98;PRO A 112","None;FES A 201 ( 3.1A); NI A 203 ( 3.2A);FES A 201 (-4.2A)","1.20A","3mbgC-5cxmA:undetectable","3mbgC-5cxmA:20.31"]]