SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 9 ARG A  90
LEU A  85
ILE A 258
PRO A  11
ILE A  81
 None
 1.08A 2avoA-5cxuA:
undetectable		 2avoA-5cxuA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		4 / 7 GLY A 166
ILE A 126
MET A 134
LEU A 152
 None
 0.94A 2xrhA-5cxuA:
undetectable		 2xrhA-5cxuA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 MET A 134
ILE A 133
ILE A 165
PRO A  99
LEU A  62
 None
 1.24A 3a51D-5cxuA:
undetectable		 3a51D-5cxuA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 MET A 134
ILE A 133
ILE A 165
PRO A  99
LEU A  62
 None
 1.23A 3a51E-5cxuA:
undetectable		 3a51E-5cxuA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 HIS A 253
ASP A 222
GLY A  64
SER A 156
ASP A 217
 None
 1.06A 3keeC-5cxuA:
undetectable		 3keeC-5cxuA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 HIS A 253
ASP A 222
GLY A  64
SER A 156
ASP A 217
 None
 0.64A 3sueC-5cxuA:
undetectable		 3sueC-5cxuA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 HIS A 253
ASP A 222
GLY A  64
SER A 156
SER A  77
 None
 0.98A 3sueD-5cxuA:
undetectable		 3sueD-5cxuA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 VAL A 225
HIS A 253
ASP A 222
GLY A  64
SER A 156
 None
 0.86A 3sufB-5cxuA:
undetectable		 3sufB-5cxuA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		4 / 7 TRP A 255
GLU A  74
TYR A  68
GLU A  69
 None
 1.30A 4r87J-5cxuA:
undetectable
4r87L-5cxuA:
undetectable		 4r87J-5cxuA:
18.66
4r87L-5cxuA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 LEU A  65
GLY A  64
PHE A 114
HIS A 196
TYR A 122
 None
 1.40A 5m6gA-5cxuA:
undetectable		 5m6gA-5cxuA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 ILE A 133
VAL A  44
LEU A 129
LEU A  62
LEU A 152
 None
 1.31A 5tiwA-5cxuA:
undetectable		 5tiwA-5cxuA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		4 / 5 ALA A 182
SER A 156
GLY A  64
TYR A 122
 None
 0.99A 5yodB-5cxuA:
undetectable		 5yodB-5cxuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		5 / 12 HIS A 253
ASP A 222
GLY A  64
SER A 156
SER A  77
 None
 0.95A 6c2mC-5cxuA:
undetectable		 6c2mC-5cxuA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		4 / 5 ARG A  90
ALA A  91
GLN A 267
ILE A  81
 None
 1.27A 6f6sA-5cxuA:
undetectable
6f6sB-5cxuA:
undetectable		 6f6sA-5cxuA:
15.55
6f6sB-5cxuA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A
(Anaeromyces
mucronatus) 		4 / 4 MET A 157
GLY A  64
HIS A  63
GLY A 158
 None
 1.38A 6fgdA-5cxuA:
undetectable		 6fgdA-5cxuA:
20.84