SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cy1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		3 / 3 LEU A  66
PHE A  92
ARG A  45
 None
 0.71A 1xdkF-5cy1A:
undetectable		 1xdkF-5cy1A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		5 / 9 ALA A  26
ASP A  25
GLY A   5
ILE A  61
ILE A  93
 None
 1.07A 3ekvB-5cy1A:
undetectable		 3ekvB-5cy1A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		5 / 9 ALA A  26
ASP A  25
GLY A   5
ILE A  61
ILE A  93
 None
 1.08A 3nuoA-5cy1A:
undetectable		 3nuoA-5cy1A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		5 / 10 ALA A  26
ASP A  25
GLY A   5
ILE A  61
ILE A  93
 None
 1.08A 4q1wB-5cy1A:
undetectable		 4q1wB-5cy1A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		4 / 6 ILE A  20
GLN A  19
ILE A  93
ASP A  94
 None
 1.20A 4w5qA-5cy1A:
3.5		 4w5qA-5cy1A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		4 / 6 ILE A  20
GLN A  19
ILE A  93
ASP A  94
 None
 1.16A 4w5tA-5cy1A:
3.5		 4w5tA-5cy1A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		4 / 6 ILE A  20
GLN A  19
ILE A  93
ASP A  94
 None
 1.19A 4z4cA-5cy1A:
undetectable		 4z4cA-5cy1A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		4 / 8 ASP A  44
TYR A   6
ASP A  36
ILE A  20
 None
 1.02A 5cfsA-5cy1A:
undetectable		 5cfsA-5cy1A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		5 / 9 ALA A  26
ASP A  25
GLY A   5
ILE A  61
ILE A  93
 None
 1.06A 5kr0A-5cy1A:
undetectable		 5kr0A-5cy1A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		5 / 10 VAL A  90
ILE A  61
LEU A  51
PHE A   4
GLY A  87
 None
 1.12A 5mxbA-5cy1A:
undetectable		 5mxbA-5cy1A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 5cy1 TRANSPOSON TN3
RESOLVASE
(Escherichia
coli) 		4 / 6 ILE A  20
GLN A  19
ILE A  93
ASP A  94
 None
 1.19A 6cbdA-5cy1A:
3.5		 6cbdA-5cy1A:
13.78