SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cyb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 5cyb LIPOPROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  95
LEU A  99
THR A  86
VAL A  88
 None
 0.43A 1ictD-5cybA:
undetectable		 1ictD-5cybA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 5cyb LIPOPROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A 150
GLY A  74
VAL A 130
VAL A 137
ILE A 135
 None
 0.94A 3ndtD-5cybA:
undetectable		 3ndtD-5cybA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 5cyb LIPOPROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A 150
GLY A  74
VAL A 130
VAL A 137
ILE A 135
 None
 0.93A 3nduC-5cybA:
undetectable		 3nduC-5cybA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 5cyb LIPOPROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A 150
GLY A  74
VAL A 130
VAL A 137
ILE A 135
 None
 0.97A 3tkgD-5cybA:
undetectable		 3tkgD-5cybA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 5cyb LIPOPROTEIN
(Streptococcus
pneumoniae) 		4 / 8 THR A  95
LEU A  99
THR A  86
VAL A  88
 None
 0.70A 4ik7B-5cybA:
undetectable		 4ik7B-5cybA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 5cyb LIPOPROTEIN
(Streptococcus
pneumoniae) 		3 / 3 LYS A 126
VAL A 137
ASP A 139
 GOL  A 201 ( 3.2A)
None
CA  A 205 ( 4.9A)
 0.60A 6fgdA-5cybA:
undetectable		 6fgdA-5cybA:
17.92