SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 5cyp SEPTIN-9
(Homo
sapiens) 		4 / 7 ASN A 213
HIS A 269
PHE A 216
ILE A 276
 None
 1.19A 1tdnA-5cypA:
undetectable		 1tdnA-5cypA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5cyp SEPTIN-9
(Homo
sapiens) 		5 / 12 THR A  64
GLY A  35
GLY A  33
GLY A  90
ASP A 172
 MG  A 302 ( 2.9A)
GSP  A 301 (-3.1A)
GSP  A 301 (-3.3A)
GSP  A 301 ( 3.8A)
GSP  A 301 (-2.6A)
 0.95A 2b25A-5cypA:
2.1		 2b25A-5cypA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5cyp SEPTIN-9
(Homo
sapiens) 		4 / 7 LEU A  43
LEU A  83
SER A  69
THR A 131
 None
 0.91A 3lm8B-5cypA:
undetectable
3lm8D-5cypA:
undetectable		 3lm8B-5cypA:
24.56
3lm8D-5cypA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)		 5cyp SEPTIN-9
(Homo
sapiens) 		5 / 9 ILE A  86
ILE A 104
PHE A 154
TYR A 138
CYH A 136
 None
 1.50A 4afgA-5cypA:
undetectable
4afgE-5cypA:
undetectable		 4afgA-5cypA:
24.11
4afgE-5cypA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5cyp SEPTIN-9
(Homo
sapiens) 		4 / 6 ILE A 273
VAL A 162
LEU A 158
CYH A 136
 None
 0.91A 4asdA-5cypA:
undetectable		 4asdA-5cypA:
23.90