SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5cyv TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		4 / 8 GLY A  80
ARG A  79
LEU A  81
LEU A 105
 None
 0.88A 2vctA-5cyvA:
undetectable		 2vctA-5cyvA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 5cyv TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		4 / 7 HIS A 117
ASN A  27
VAL A 113
ALA A 116
 None
 0.90A 4p6sA-5cyvA:
undetectable		 4p6sA-5cyvA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cyv TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		6 / 12 HIS A 117
LEU A 136
VAL A  22
GLY A  20
SER A  16
LEU A  15
 None
 1.34A 5jw1A-5cyvA:
undetectable		 5jw1A-5cyvA:
14.31