SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cyw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	5cyw	INTERFERON ANTAGONIST C7 (Vaccinia virus)	5 / 12	LEU B 61 LEU B 98 GLU B 96 LEU B 20 PHE B 44	None	1.29A	1s9pB-5cywB: undetectable	1s9pB-5cywB: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_B_SAMB801_0 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	5cyw	INTERFERON ANTAGONIST C7 (Vaccinia virus)	5 / 12	GLY B 29 ASP B 103 LEU B 61 ASP B 8 LEU B 20	None	1.24A	2zw9B-5cywB: undetectable	2zw9B-5cywB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJG_D_NCTD501_1 (CYTOCHROME P450 2A13)	5cyw	INTERFERON ANTAGONIST C7 (Vaccinia virus)	4 / 6	PHE B 44 ALA B 65 THR B 95 LEU B 90	None None None GOL B 201 (-4.9A)	1.00A	4ejgD-5cywB: undetectable	4ejgD-5cywB: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_H_CVIH301_1 (REGULATORY PROTEIN TETR)	5cyw	INTERFERON ANTAGONIST C7 (Vaccinia virus)	4 / 8	GLN B 4 GLY B 25 ILE B 55 ASP B 102	None	1.00A	5vlmH-5cywB: undetectable	5vlmH-5cywB: 19.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9P_B_DESB459_1","ESTROGEN-RELATED RECEPTOR GAMMA","5cyw","INTERFERON ANTAGONIST C7","Vaccinia virus",5,"LEU B  61;LEU B  98;GLU B  96;LEU B  20;PHE B  44","None","1.29A","1s9pB-5cywB:undetectable","1s9pB-5cywB:19.91"],["2ZW9_B_SAMB801_0","LEUCINE CARBOXYL METHYLTRANSFERASE 2","5cyw","INTERFERON ANTAGONIST C7","Vaccinia virus",5,"GLY B  29;ASP B 103;LEU B  61;ASP B   8;LEU B  20","None","1.24A","2zw9B-5cywB:undetectable","2zw9B-5cywB:13.64"],["4EJG_D_NCTD501_1","CYTOCHROME P450 2A13","5cyw","INTERFERON ANTAGONIST C7","Vaccinia virus",4,"PHE B  44;ALA B  65;THR B  95;LEU B  90","None;None;None;GOL B 201 (-4.9A)","1.00A","4ejgD-5cywB:undetectable","4ejgD-5cywB:17.43"],["5VLM_H_CVIH301_1","REGULATORY PROTEIN TETR","5cyw","INTERFERON ANTAGONIST C7","Vaccinia virus",4,"GLN B   4;GLY B  25;ILE B  55;ASP B 102","None","1.00A","5vlmH-5cywB:undetectable","5vlmH-5cywB:19.29"]]