SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CIZ_A_ACTA1321_0 (CHLOROPEROXIDASE)	5cz1	INTEGRASE (Mouse mammary tumor virus)	4 / 5	LEU A 188 ASN A 192 PHE A 88 ALA A 91	None	1.22A	2cizA-5cz1A: undetectable	2cizA-5cz1A: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LJ0_A_ACTA505_0 (NAB2)	5cz1	INTEGRASE (Mouse mammary tumor virus)	3 / 3	LEU A 103 LYS A 100 THR A 99	None	0.63A	4lj0A-5cz1A: undetectable	4lj0A-5cz1A: 14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESG_A_1YNA701_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5cz1	INTEGRASE (Mouse mammary tumor virus)	4 / 4	LEU A 213 TYR A 85 PRO A 58 ILE A 115	None	1.15A	5esgA-5cz1A: 1.6	5esgA-5cz1A: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBS_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	5cz1	INTEGRASE (Mouse mammary tumor virus)	4 / 8	LEU A 188 LEU A 168 THR A 67 GLN A 154	None	1.15A	5hbsA-5cz1A: 1.1	5hbsA-5cz1A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNA_A_BZMA301_0 (ISATIN HYDROLASE A)	5cz1	INTEGRASE (Mouse mammary tumor virus)	5 / 12	LEU A 188 HIS A 105 SER A 86 VAL A 82 TYR A 112	None	1.09A	5nnaA-5cz1A: undetectable	5nnaA-5cz1A: 22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNA_D_BZMD301_0 (ISATIN HYDROLASE A)	5cz1	INTEGRASE (Mouse mammary tumor virus)	5 / 12	LEU A 188 HIS A 105 SER A 86 VAL A 82 TYR A 112	None	1.13A	5nnaD-5cz1A: undetectable	5nnaD-5cz1A: 22.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CIZ_A_ACTA1321_0","CHLOROPEROXIDASE","5cz1","INTEGRASE","Mouse mammary tumor virus",4,"LEU A 188;ASN A 192;PHE A  88;ALA A  91","None","1.22A","2cizA-5cz1A:undetectable","2cizA-5cz1A:19.33"],["4LJ0_A_ACTA505_0","NAB2","5cz1","INTEGRASE","Mouse mammary tumor virus",3,"LEU A 103;LYS A 100;THR A  99","None","0.63A","4lj0A-5cz1A:undetectable","4lj0A-5cz1A:14.09"],["5ESG_A_1YNA701_2","LANOSTEROL 14-ALPHA DEMETHYLASE","5cz1","INTEGRASE","Mouse mammary tumor virus",4,"LEU A 213;TYR A  85;PRO A  58;ILE A 115","None","1.15A","5esgA-5cz1A:1.6","5esgA-5cz1A:14.88"],["5HBS_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","5cz1","INTEGRASE","Mouse mammary tumor virus",4,"LEU A 188;LEU A 168;THR A  67;GLN A 154","None","1.15A","5hbsA-5cz1A:1.1","5hbsA-5cz1A:19.76"],["5NNA_A_BZMA301_0","ISATIN HYDROLASE A","5cz1","INTEGRASE","Mouse mammary tumor virus",5,"LEU A 188;HIS A 105;SER A  86;VAL A  82;TYR A 112","None","1.09A","5nnaA-5cz1A:undetectable","5nnaA-5cz1A:22.93"],["5NNA_D_BZMD301_0","ISATIN HYDROLASE A","5cz1","INTEGRASE","Mouse mammary tumor virus",5,"LEU A 188;HIS A 105;SER A  86;VAL A  82;TYR A 112","None","1.13A","5nnaD-5cz1A:undetectable","5nnaD-5cz1A:22.93"]]