SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.10A 1p7lC-5cz3A:
undetectable		 1p7lC-5cz3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.09A 1p7lD-5cz3A:
undetectable		 1p7lD-5cz3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.10A 1rg9A-5cz3A:
undetectable		 1rg9A-5cz3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.09A 1rg9B-5cz3A:
undetectable		 1rg9B-5cz3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.11A 1rg9C-5cz3A:
undetectable		 1rg9C-5cz3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.10A 1rg9D-5cz3A:
undetectable		 1rg9D-5cz3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 ASP A  29
GLY A  32
ASP A  10
THR A 135
 None
 0.90A 2aouA-5cz3A:
undetectable		 2aouA-5cz3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.15A 2obvA-5cz3A:
undetectable		 2obvA-5cz3A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.16A 2p02A-5cz3A:
undetectable		 2p02A-5cz3A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 5cz3 M64R
(Myxoma
virus) 		5 / 12 ASP A  10
ILE A  20
VAL A  18
PHE A 116
TYR A 136
 None
 1.15A 3a8iA-5cz3A:
undetectable		 3a8iA-5cz3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 5cz3 M64R
(Myxoma
virus) 		5 / 12 ASP A  10
ILE A  20
VAL A  18
PHE A 116
TYR A 136
 None
 1.07A 3a8iB-5cz3A:
undetectable		 3a8iB-5cz3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 5cz3 M64R
(Myxoma
virus) 		5 / 12 ASP A  10
ILE A  20
VAL A  18
PHE A 116
TYR A 136
 None
 1.18A 3a8iD-5cz3A:
undetectable		 3a8iD-5cz3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 5cz3 M64R
(Myxoma
virus) 		3 / 3 GLU A  94
VAL A  93
CYH A  42
 BME  A 301 (-4.3A)
None
BME  A 301 (-1.8A)
 1.06A 3fbxA-5cz3A:
undetectable		 3fbxA-5cz3A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.15A 4kttC-5cz3A:
undetectable		 4kttC-5cz3A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 7 ASN A  24
VAL A  50
GLU A  52
ARG A 148
 None
 0.89A 4mv7A-5cz3A:
undetectable		 4mv7A-5cz3A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.15A 4ndnA-5cz3A:
undetectable		 4ndnA-5cz3A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5cz3 M64R
(Myxoma
virus) 		5 / 12 MET A  66
LEU A  49
ILE A  35
LEU A  13
ILE A  45
 None
 1.14A 4nx6A-5cz3A:
undetectable		 4nx6A-5cz3A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 5cz3 M64R
(Myxoma
virus) 		5 / 12 MET A  66
LEU A  49
ILE A  35
LEU A  13
ILE A  45
 None
 1.07A 4nx7A-5cz3A:
undetectable		 4nx7A-5cz3A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.18A 5a1iA-5cz3A:
undetectable		 5a1iA-5cz3A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 5cz3 M64R
(Myxoma
virus) 		5 / 11 ALA A  99
ALA A  97
VAL A  93
LEU A  37
LEU A  13
 None
 1.12A 5eb5A-5cz3A:
undetectable		 5eb5A-5cz3A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.05A 5t8sB-5cz3A:
undetectable		 5t8sB-5cz3A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.10A 6fbnB-5cz3A:
undetectable		 6fbnB-5cz3A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.17A 6fboA-5cz3A:
undetectable		 6fboA-5cz3A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5cz3 M64R
(Myxoma
virus) 		4 / 8 HIS A  22
ASP A  10
SER A  19
PHE A  12
 None
 1.17A 6fcdA-5cz3A:
undetectable		 6fcdA-5cz3A:
15.66