SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5czf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		3 / 3 VAL C  81
VAL C  79
TRP C   6
 None
 0.92A 1av2C-5czfC:
undetectable
1av2D-5czfC:
undetectable		 1av2C-5czfC:
14.29
1av2D-5czfC:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		3 / 3 VAL C  81
VAL C  79
TRP C   6
 None
 0.91A 1w5uC-5czfC:
undetectable
1w5uD-5czfC:
undetectable		 1w5uC-5czfC:
14.29
1w5uD-5czfC:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		3 / 3 VAL C  79
TRP C   6
VAL C  81
 None
 0.94A 2izqA-5czfC:
undetectable
2izqB-5czfC:
undetectable		 2izqA-5czfC:
14.29
2izqB-5czfC:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		3 / 3 LEU C   2
PRO C   3
ARG C  73
 None
 0.58A 2qd4B-5czfC:
undetectable		 2qd4B-5czfC:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		3 / 3 VAL C  81
VAL C  79
TRP C   6
 None
 0.84A 3l8lA-5czfC:
undetectable
3l8lB-5czfC:
undetectable		 3l8lA-5czfC:
14.29
3l8lB-5czfC:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		3 / 3 VAL C  81
VAL C  79
TRP C   6
 None
 0.88A 3l8lC-5czfC:
undetectable
3l8lD-5czfC:
undetectable		 3l8lC-5czfC:
14.29
3l8lD-5czfC:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		4 / 7 GLU C  80
TYR C  72
GLY C  58
ARG C  73
 None
 0.97A 4fgzA-5czfC:
undetectable		 4fgzA-5czfC:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		4 / 8 VAL C  40
VAL C   4
TRP C  33
LEU C  14
 None
 0.86A 4jq1B-5czfC:
undetectable		 4jq1B-5czfC:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		4 / 6 VAL C  40
VAL C   4
TRP C  33
LEU C  14
 None
 0.98A 4l1wB-5czfC:
undetectable		 4l1wB-5czfC:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5czf PLASMID
STABILIZATION
PROTEIN PARE
(Escherichia
coli) 		4 / 8 LEU C  71
VAL C  40
LEU C  43
ILE C  62
 None
 0.78A 4r38A-5czfC:
undetectable		 4r38A-5czfC:
21.19