SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5czj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3001_1
(SERUM ALBUMIN)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		5 / 11 TYR A 296
LEU A  87
ARG A  86
LEU A  33
ALA A  47
 None
 1.49A 1hk1A-5czjA:
2.1		 1hk1A-5czjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		5 / 9 TYR A 296
GLU A 295
LEU A  87
LEU A  33
ALA A  54
 None
 1.16A 2bxcB-5czjA:
undetectable		 2bxcB-5czjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		5 / 9 TYR A 296
LEU A  87
LEU A  33
ALA A  54
ALA A  47
 None
 1.38A 2bxcB-5czjA:
undetectable		 2bxcB-5czjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		5 / 10 LEU A  87
VAL A  92
GLY A  91
GLY A  83
LEU A  48
 None
 0.84A 2v3kA-5czjA:
undetectable		 2v3kA-5czjA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		4 / 7 VAL A  49
LYS A  53
ILE A  56
GLY A  59
 None
 0.75A 3bjwF-5czjA:
undetectable		 3bjwF-5czjA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		3 / 3 ASN A 301
HIS A 299
VAL A 281
 None
 0.56A 3elzB-5czjA:
undetectable		 3elzB-5czjA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A  97
GLY A  67
ALA A 110
HIS A 140
ILE A 144
 None
 0.94A 3fuuA-5czjA:
undetectable		 3fuuA-5czjA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		4 / 6 HIS A 109
ARG A  80
PHE A  45
PRO A  43
 None
 1.49A 3gclA-5czjA:
undetectable		 3gclA-5czjA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		4 / 6 LEU A 243
GLN A 266
LEU A 268
GLU A 265
 None
 1.09A 3h5gB-5czjA:
undetectable
3h5gC-5czjA:
undetectable		 3h5gB-5czjA:
7.21
3h5gC-5czjA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		5 / 11 ILE A 134
ALA A 136
PHE A 163
ILE A 155
LEU A 169
 None
 1.32A 3qg2B-5czjA:
undetectable		 3qg2B-5czjA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		4 / 5 GLU A 336
GLY A 333
TYR A 338
ASP A 254
 None
 1.19A 3w9tD-5czjA:
undetectable		 3w9tD-5czjA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		4 / 5 ILE A 124
PHE A 300
HIS A 140
ASP A  77
 None
 1.38A 4rzvB-5czjA:
undetectable		 4rzvB-5czjA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		4 / 6 GLY A  97
ASP A 275
ILE A 210
TYR A 161
 None
 1.11A 5iwuA-5czjA:
undetectable		 5iwuA-5czjA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		3 / 3 THR A 226
SER A 207
ASP A 203
 None
 0.63A 5kvaA-5czjA:
2.9		 5kvaA-5czjA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		3 / 3 THR A 226
SER A 207
ASP A 203
 None
 0.62A 5kvaB-5czjA:
2.9		 5kvaB-5czjA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 5czj DIHYDRODIPICOLINATE
SYNTHASE
(Sinorhizobium
meliloti) 		3 / 3 HIS A 242
ASN A 245
ALA A 249
 None
 0.34A 5n4tB-5czjA:
3.9		 5n4tB-5czjA:
25.69