SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5czl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 12 LEU A 306
LEU A 309
LEU A 312
ALA A 313
ARG A 106
 None
 0.91A 1s9pC-5czlA:
undetectable		 1s9pC-5czlA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 12 LEU A 306
LEU A 309
LEU A 312
ALA A 313
ARG A 106
 None
 1.01A 1ya3C-5czlA:
undetectable		 1ya3C-5czlA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 12 ALA A  11
LEU A  46
ALA A  49
ILE A  26
LEU A  59
 None
 1.02A 3dauA-5czlA:
undetectable		 3dauA-5czlA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		4 / 6 THR A  94
SER A 126
LEU A 127
THR A 131
 None
 0.83A 3deuB-5czlA:
undetectable		 3deuB-5czlA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		3 / 3 TYR A 160
ASP A  97
HIS A  36
 None
 0.95A 3e23A-5czlA:
undetectable		 3e23A-5czlA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 12 ASP A 121
ILE A 123
ILE A 162
TYR A 232
MET A  44
 None
 1.27A 4a84A-5czlA:
undetectable		 4a84A-5czlA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		4 / 6 SER A 120
ASP A 121
THR A 173
PHE A 169
 None
 0.88A 4acbC-5czlA:
undetectable		 4acbC-5czlA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		3 / 3 ARG A  25
ASP A  23
TRP A  62
 None
 1.13A 4xdqA-5czlA:
undetectable		 4xdqA-5czlA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		3 / 3 ASP A  57
SER A 115
TYR A 116
 None
 0.73A 5glmA-5czlA:
undetectable		 5glmA-5czlA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 10 LEU A 243
PRO A 230
VAL A 281
LEU A 284
THR A 286
 None
 1.01A 5o96G-5czlA:
undetectable
5o96H-5czlA:
undetectable		 5o96G-5czlA:
21.55
5o96H-5czlA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 12 GLY A  30
LEU A 309
GLY A  39
SER A  35
ILE A  26
 None
 1.15A 5vooE-5czlA:
undetectable		 5vooE-5czlA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 12 GLY A 210
ASP A 209
ALA A 136
LEU A 206
ALA A 205
 None
 0.81A 6bq4A-5czlA:
undetectable		 6bq4A-5czlA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		5 / 12 GLY A 210
ASP A 209
ALA A 136
LEU A 206
ALA A 205
 None
 0.79A 6bq4B-5czlA:
undetectable		 6bq4B-5czlA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 5czl GLUCANASE
(Raoultella
ornithinolytica) 		4 / 5 PHE A 250
VAL A 264
PRO A 259
MET A 274
 None
 1.32A 6ekzA-5czlA:
undetectable		 6ekzA-5czlA:
13.27