SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5czw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.29A 1os2A-5czwA:
11.2
1os2A-5czwA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.33A 1os2D-5czwA:
11.2
1os2D-5czwA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)
5czw MYROILYSIN
(Myroides
profundi)
6 / 10 ALA A  25
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
MLY  A  26 ( 3.5A)
None
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.75A 1r55A-5czwA:
7.1
1r55A-5czwA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.33A 1uttA-5czwA:
11.8
1uttA-5czwA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.26A 1utzA-5czwA:
11.5
1utzA-5czwA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.32A 1utzB-5czwA:
11.4
1utzB-5czwA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.33A 1y93A-5czwA:
11.4
1y93A-5czwA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 TRP A 179
THR A 191
TYR A 192
None
1.16A 2a3aA-5czwA:
undetectable
2a3aA-5czwA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 TRP A 179
THR A 191
TYR A 192
None
1.15A 2a3aB-5czwA:
undetectable
2a3aB-5czwA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 TRP A 179
THR A 191
TYR A 192
None
1.16A 2a3bA-5czwA:
undetectable
2a3bA-5czwA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 ALA A  73
ILE A  54
VAL A  56
PHE A  86
MLY  A  70 ( 3.8A)
None
None
MLY  A  70 ( 4.0A)
0.94A 2cizA-5czwA:
undetectable
2cizA-5czwA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 10 TYR A 175
GLY A 125
ALA A 102
TYR A 107
VAL A  31
None
1.16A 2coiA-5czwA:
undetectable
2coiB-5czwA:
undetectable
2coiA-5czwA:
19.03
2coiB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 10 TYR A 175
GLY A 125
THR A  99
TYR A 107
VAL A  31
None
1.25A 2coiA-5czwA:
undetectable
2coiB-5czwA:
undetectable
2coiA-5czwA:
19.03
2coiB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 10 TYR A 107
VAL A  31
TYR A 175
GLY A 125
ALA A 102
None
1.24A 2coiA-5czwA:
undetectable
2coiB-5czwA:
undetectable
2coiA-5czwA:
19.03
2coiB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 10 TYR A 107
VAL A  31
TYR A 175
GLY A 125
THR A  99
None
1.33A 2coiA-5czwA:
undetectable
2coiB-5czwA:
undetectable
2coiA-5czwA:
19.03
2coiB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 11 TYR A 175
GLY A 125
ALA A 102
TYR A 107
VAL A  31
None
1.19A 2cojA-5czwA:
undetectable
2cojB-5czwA:
undetectable
2cojA-5czwA:
19.03
2cojB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 11 TYR A 175
GLY A 125
THR A  99
TYR A 107
VAL A  31
None
1.30A 2cojA-5czwA:
undetectable
2cojB-5czwA:
undetectable
2cojA-5czwA:
19.03
2cojB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 9 TYR A 107
VAL A  31
TYR A 175
GLY A 125
ALA A 102
None
1.23A 2cojA-5czwA:
undetectable
2cojB-5czwA:
undetectable
2cojA-5czwA:
19.03
2cojB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5czw MYROILYSIN
(Myroides
profundi)
5 / 9 TYR A 107
VAL A  31
TYR A 175
GLY A 125
THR A  99
None
1.34A 2cojA-5czwA:
undetectable
2cojB-5czwA:
undetectable
2cojA-5czwA:
19.03
2cojB-5czwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_D_H4BD1006_1
(HYPOTHETICAL PROTEIN
PH0634)
5czw MYROILYSIN
(Myroides
profundi)
5 / 10 HIS A 152
HIS A 146
THR A 139
GLU A 135
GLU A 143
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.3A)
None
MLY  A  26 ( 4.2A)
ZN  A 301 ( 4.2A)
1.19A 2dttD-5czwA:
undetectable
2dttF-5czwA:
undetectable
2dttD-5czwA:
16.25
2dttF-5czwA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 THR A  99
PRO A  14
TYR A 175
None
0.87A 2dxrA-5czwA:
undetectable
2dxrA-5czwA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.32A 2hu6A-5czwA:
11.4
2hu6A-5czwA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)
5czw MYROILYSIN
(Myroides
profundi)
5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
None
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.37A 2jihA-5czwA:
7.1
2jihA-5czwA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)
5czw MYROILYSIN
(Myroides
profundi)
5 / 8 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
None
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.33A 2jihB-5czwA:
2.9
2jihB-5czwA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.17A 2ow9A-5czwA:
11.1
2ow9A-5czwA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.21A 2ow9B-5czwA:
11.1
2ow9B-5czwA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.18A 2ozrC-5czwA:
10.9
2ozrC-5czwA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.20A 2ozrD-5czwA:
11.0
2ozrD-5czwA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.36A 2ozrE-5czwA:
11.0
2ozrE-5czwA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 HIS A 142
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.31A 2ozrF-5czwA:
10.9
2ozrF-5czwA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)
5czw MYROILYSIN
(Myroides
profundi)
4 / 7 ILE A 151
TYR A 199
PHE A 236
ASP A 233
None
1.14A 2qebB-5czwA:
undetectable
2qebB-5czwA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 SER A 211
TYR A 210
HIS A 209
None
0.82A 2r2vD-5czwA:
undetectable
2r2vD-5czwA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.25A 2y69C-5czwA:
undetectable
2y69J-5czwA:
undetectable
2y69C-5czwA:
21.15
2y69J-5czwA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.00A 2y69C-5czwA:
undetectable
2y69J-5czwA:
undetectable
2y69C-5czwA:
21.15
2y69J-5czwA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.22A 2y69P-5czwA:
undetectable
2y69W-5czwA:
undetectable
2y69P-5czwA:
21.15
2y69W-5czwA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.28A 3abmC-5czwA:
undetectable
3abmJ-5czwA:
undetectable
3abmC-5czwA:
21.15
3abmJ-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.02A 3abmC-5czwA:
undetectable
3abmJ-5czwA:
undetectable
3abmC-5czwA:
21.15
3abmJ-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.21A 3abmP-5czwA:
undetectable
3abmW-5czwA:
undetectable
3abmP-5czwA:
21.15
3abmW-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
0.97A 3abmP-5czwA:
undetectable
3abmW-5czwA:
undetectable
3abmP-5czwA:
21.15
3abmW-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.22A 3ag3C-5czwA:
undetectable
3ag3J-5czwA:
undetectable
3ag3C-5czwA:
21.15
3ag3J-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.09A 3ag3C-5czwA:
undetectable
3ag3J-5czwA:
undetectable
3ag3C-5czwA:
21.15
3ag3J-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 HIS A 152
HIS A 146
HIS A 142
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.4A)
0.73A 3bvdA-5czwA:
undetectable
3bvdA-5czwA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)
5czw MYROILYSIN
(Myroides
profundi)
5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
None
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.32A 3hy7A-5czwA:
7.8
3hy7A-5czwA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)
5czw MYROILYSIN
(Myroides
profundi)
5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
None
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.32A 3hy7B-5czwA:
7.5
3hy7B-5czwA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.23A 3kecA-5czwA:
11.1
3kecA-5czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 HIS A 142
GLU A 143
HIS A 146
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
0.12A 3kecB-5czwA:
11.0
3kecB-5czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.31A 3likA-5czwA:
11.3
3likA-5czwA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.31A 3lilA-5czwA:
11.4
3lilA-5czwA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.36A 3ljgA-5czwA:
11.5
3ljgA-5czwA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.30A 3lkaA-5czwA:
11.4
3lkaA-5czwA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 HIS A 152
HIS A 146
HIS A 142
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.4A)
0.77A 3s38A-5czwA:
undetectable
3s38A-5czwA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 HIS A 152
HIS A 146
HIS A 142
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.4A)
0.80A 3s3aA-5czwA:
undetectable
3s3aA-5czwA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)
5czw MYROILYSIN
(Myroides
profundi)
5 / 10 PHE A 124
PHE A 127
PHE A  98
ALA A  73
ILE A  94
None
None
None
MLY  A  70 ( 3.8A)
None
1.45A 3t3qD-5czwA:
undetectable
3t3qD-5czwA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.12A 4a7bA-5czwA:
10.9
4a7bA-5czwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 GLN A 196
THR A 195
THR A 194
None
0.80A 4fu9A-5czwA:
undetectable
4fu9A-5czwA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 GLN A 196
THR A 195
THR A 194
None
0.79A 4fufA-5czwA:
undetectable
4fufA-5czwA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 7 ILE A  94
LEU A 148
GLY A 145
PHE A 144
None
0.86A 4iqqB-5czwA:
undetectable
4iqqB-5czwA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 7 ILE A  94
LEU A 148
GLY A 145
PHE A 144
None
0.70A 4iqqC-5czwA:
undetectable
4iqqC-5czwA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 GLU A 153
GLN A 198
VAL A 240
THR A 239
None
None
MLY  A  47 ( 4.7A)
None
1.30A 4lnxA-5czwA:
undetectable
4lnxA-5czwA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 PHE A  86
PRO A  92
PHE A 144
SER A 106
GLY A 109
MLY  A  70 ( 4.0A)
None
None
None
None
1.21A 4olfA-5czwA:
undetectable
4olfA-5czwA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PRO A  92
PHE A 144
SER A 106
GLY A 109
None
1.08A 4q15A-5czwA:
undetectable
4q15A-5czwA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PRO A  92
PHE A 144
SER A 106
GLY A 109
None
1.12A 4q15B-5czwA:
undetectable
4q15B-5czwA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PHE A  86
PHE A 144
SER A 106
GLY A 109
None
MLY  A  70 ( 4.0A)
None
None
None
1.23A 4ydqA-5czwA:
undetectable
4ydqA-5czwA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PRO A  92
PHE A 144
SER A 106
GLY A 109
None
1.11A 4ydqA-5czwA:
undetectable
4ydqA-5czwA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 ALA A 170
TYR A 169
HIS A 156
PHE A 189
None
MLY  A 181 ( 3.9A)
None
None
1.03A 4ze2A-5czwA:
undetectable
4ze2A-5czwA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)
5czw MYROILYSIN
(Myroides
profundi)
4 / 8 ASN A 219
PRO A 162
PHE A 221
SER A 214
None
1.36A 5amiB-5czwA:
undetectable
5amiB-5czwA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 GLU A 143
TRP A  76
ASN A 225
ZN  A 301 ( 4.2A)
None
None
0.85A 5dv4A-5czwA:
undetectable
5dv4A-5czwA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PRO A  92
PHE A 144
SER A 106
GLY A 109
None
1.12A 5f9zA-5czwA:
undetectable
5f9zA-5czwA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PRO A  92
PHE A 144
SER A 106
GLY A 109
None
1.16A 5f9zB-5czwA:
undetectable
5f9zB-5czwA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.31A 5n5jA-5czwA:
11.5
5n5jA-5czwA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.2A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.1A)
0.30A 5n5kA-5czwA:
11.1
5n5kA-5czwA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 7 ILE A  94
LEU A 148
GLY A 145
PHE A 144
None
0.88A 5nooB-5czwA:
undetectable
5nooB-5czwA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 8 ALA A 112
GLN A  93
ILE A  54
ILE A  82
None
0.96A 5t8sA-5czwA:
undetectable
5t8sA-5czwA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.21A 5wauC-5czwA:
undetectable
5wauJ-5czwA:
undetectable
5wauC-5czwA:
21.15
5wauJ-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.08A 5wauC-5czwA:
undetectable
5wauJ-5czwA:
undetectable
5wauC-5czwA:
21.15
5wauJ-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.23A 5wauc-5czwA:
undetectable
5wauj-5czwA:
undetectable
5wauc-5czwA:
21.15
5wauj-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.04A 5wauc-5czwA:
undetectable
5wauj-5czwA:
undetectable
5wauc-5czwA:
21.15
5wauj-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.18A 5xdqC-5czwA:
undetectable
5xdqJ-5czwA:
undetectable
5xdqC-5czwA:
21.15
5xdqJ-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
0.98A 5xdqC-5czwA:
undetectable
5xdqJ-5czwA:
undetectable
5xdqC-5czwA:
21.15
5xdqJ-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A  84
PHE A  86
LEU A  58
PHE A  98
None
MLY  A  70 ( 4.0A)
None
None
1.21A 5xdqP-5czwA:
undetectable
5xdqW-5czwA:
undetectable
5xdqP-5czwA:
21.15
5xdqW-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 5 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.01A 5xdqP-5czwA:
undetectable
5xdqW-5czwA:
undetectable
5xdqP-5czwA:
21.15
5xdqW-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PRO A  92
PHE A 144
SER A 106
GLY A 109
None
1.07A 5xipA-5czwA:
undetectable
5xipA-5czwA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PHE A  86
PRO A  92
SER A 106
GLY A 109
None
MLY  A  70 ( 4.0A)
None
None
None
1.01A 5xiqA-5czwA:
undetectable
5xiqA-5czwA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
5czw MYROILYSIN
(Myroides
profundi)
5 / 12 LEU A   7
PRO A  92
PHE A 144
SER A 106
GLY A 109
None
1.07A 5xiqA-5czwA:
undetectable
5xiqA-5czwA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.01A 5z84P-5czwA:
undetectable
5z84W-5czwA:
undetectable
5z84P-5czwA:
21.15
5z84W-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.08A 5z85P-5czwA:
undetectable
5z85W-5czwA:
undetectable
5z85P-5czwA:
21.15
5z85W-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.01A 5z86C-5czwA:
undetectable
5z86J-5czwA:
undetectable
5z86C-5czwA:
21.15
5z86J-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
0.99A 5z86P-5czwA:
undetectable
5z86W-5czwA:
undetectable
5z86P-5czwA:
21.15
5z86W-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
0.99A 5zcoP-5czwA:
undetectable
5zcoW-5czwA:
undetectable
5zcoP-5czwA:
21.15
5zcoW-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5czw MYROILYSIN
(Myroides
profundi)
4 / 6 PHE A 127
PHE A  98
LEU A  58
PHE A  86
None
None
None
MLY  A  70 ( 4.0A)
1.00A 5zcpC-5czwA:
undetectable
5zcpJ-5czwA:
undetectable
5zcpC-5czwA:
21.15
5zcpJ-5czwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)
5czw MYROILYSIN
(Myroides
profundi)
4 / 4 HIS A 142
CYH A  28
HIS A 152
HIS A 146
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.3A)
1.44A 5zrdA-5czwA:
undetectable
5zrdA-5czwA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEE_B_RXMB601_0
(SCAFFOLD PROTEIN D13)
5czw MYROILYSIN
(Myroides
profundi)
5 / 9 GLU A 143
PHE A 144
PHE A 124
VAL A  13
VAL A  69
ZN  A 301 ( 4.2A)
None
None
None
MLY  A  70 ( 3.0A)
1.40A 6beeA-5czwA:
0.0
6beeB-5czwA:
0.0
6beeC-5czwA:
0.0
6beeA-5czwA:
19.35
6beeB-5czwA:
19.35
6beeC-5czwA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
5czw MYROILYSIN
(Myroides
profundi)
3 / 3 HIS A 152
HIS A 146
HIS A 142
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 3.4A)
0.77A 6hu9m-5czwA:
undetectable
6hu9m-5czwA:
18.36