SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5czz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4G_A_ZMRA466_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.33A	1a4gA-5czzA: undetectable	1a4gA-5czzA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4G_B_ZMRB466_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.33A	1a4gB-5czzA: undetectable	1a4gB-5czzA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D0V_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	GLY A 222 PHE A 221 SER A 219 GLY A 214	None C B 15 ( 3.7A) C B 67 ( 2.5A) C B 15 ( 3.4A)	0.62A	1d0vA-5czzA: undetectable	1d0vA-5czzA: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FO4_B_SALB4005_1 (XANTHINE DEHYDROGENASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	SER A 453 ARG A 774 PHE A 36 VAL A 449	None U B 72 ( 3.1A) None None	1.09A	1fo4B-5czzA: 2.8	1fo4B-5czzA: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_A_NOVA400_2 (DNA GYRASE SUBUNIT B)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	3 / 3	ASN A 968 PHE A 914 VAL A 981	None	0.78A	1kijA-5czzA: undetectable	1kijA-5czzA: 17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIN_A_TFPA154_1 (CALMODULIN)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	LEU A 112 GLU A 179 LEU A 96 GLU A 152	None	1.08A	1linA-5czzA: undetectable	1linA-5czzA: 10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NNC_A_ZMRA479_1 (NEURAMINIDASE N9)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.32A	1nncA-5czzA: undetectable	1nncA-5czzA: 14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P33_C_MTXC353_1 (PTERIDINE REDUCTASE 1)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	SER A 246 LEU A 355 TYR A 389 LEU A 371 LEU A 347	None	1.27A	1p33C-5czzA: undetectable	1p33C-5czzA: 13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_B_ADNB1502_1 (CLASS B ACID PHOSPHATASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	PHE A 197 LEU A 71 THR A 200 TYR A 201	None	1.08A	1rmtB-5czzA: undetectable	1rmtB-5czzA: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_D_ADND1504_1 (CLASS B ACID PHOSPHATASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	PHE A 197 LEU A 71 THR A 200 TYR A 201	None	1.12A	1rmtD-5czzA: undetectable	1rmtD-5czzA: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZGY_A_BRLA503_2 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 5	ILE A 707 ILE A 753 ILE A 760 LEU A 646	None	0.89A	1zgyA-5czzA: undetectable	1zgyA-5czzA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AZQ_A_PCFA954_0 (CATECHOL 1,2-DIOXYGENASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 9	LEU A 70 HIS A 111 ALA A 113 GLU A 179 LEU A 183	None A B 50 ( 3.9A) None None None	1.42A	2azqA-5czzA: undetectable	2azqA-5czzA: 14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AZQ_A_PCFA954_0 (CATECHOL 1,2-DIOXYGENASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 9	LEU A1035 HIS A 701 ALA A 702 LEU A 706 GLU A 477	None	1.10A	2azqA-5czzA: undetectable	2azqA-5czzA: 14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B60_B_RITB100_1 (GAG-POL POLYPROTEIN)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 34 GLY A 19 ILE A 465 ILE A 476 ILE A 464	None	0.88A	2b60A-5czzA: undetectable	2b60A-5czzA: 6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CDQ_A_SAMA1500_0 (ASPARTOKINASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	ILE A 283 ARG A 269 LEU A 275 GLU A 279	None	0.89A	2cdqA-5czzA: 1.9	2cdqA-5czzA: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_A_ZMRA1477_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.33A	2cmlA-5czzA: undetectable	2cmlA-5czzA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_B_ZMRB2477_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.31A	2cmlB-5czzA: undetectable	2cmlB-5czzA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_C_ZMRC3477_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.38A	2cmlC-5czzA: undetectable	2cmlC-5czzA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_D_ZMRD4477_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.33A	2cmlD-5czzA: undetectable	2cmlD-5czzA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_A_J01A1249_1 (CLAVALDEHYDE DEHYDROGENASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	LEU A 395 ILE A 417 ALA A 399 TYR A 239 TYR A 256	A B 4 ( 4.6A) None None A B 3 ( 4.8A) A B 4 ( 4.4A)	1.18A	2japA-5czzA: 2.3	2japA-5czzA: 11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_B_J01B1249_1 (CLAVALDEHYDE DEHYDROGENASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	LEU A 395 ILE A 417 ALA A 399 TYR A 239 TYR A 256	A B 4 ( 4.6A) None None A B 3 ( 4.8A) A B 4 ( 4.4A)	1.22A	2japB-5czzA: 3.0	2japB-5czzA: 11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_C_J01C1249_1 (CLAVALDEHYDE DEHYDROGENASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	LEU A 395 ILE A 417 ALA A 399 TYR A 239 TYR A 256	A B 4 ( 4.6A) None None A B 3 ( 4.8A) A B 4 ( 4.4A)	1.17A	2japC-5czzA: 2.4	2japC-5czzA: 11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_D_J01D1249_1 (CLAVALDEHYDE DEHYDROGENASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	LEU A 395 ILE A 417 ALA A 399 TYR A 239 TYR A 256	A B 4 ( 4.6A) None None A B 3 ( 4.8A) A B 4 ( 4.4A)	1.19A	2japD-5czzA: 3.1	2japD-5czzA: 11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNH_A_9CRA502_1 (CYTOCHROME P450 2C8)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	SER A 457 ILE A 461 LEU A 7 VAL A 673 ILE A 708	None	1.03A	2nnhA-5czzA: 1.5	2nnhA-5czzA: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O01_A_PQNA5001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	PHE A 454 SER A 457 ALA A 479 LEU A 478	None	1.07A	2o01A-5czzA: undetectable	2o01A-5czzA: 20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4K_A_DR7A301_1 (PROTEASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	GLY A 19 GLY A 8 ILE A 475 PRO A 471 ILE A 461	None	1.08A	2o4kA-5czzA: undetectable	2o4kA-5czzA: 6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ERD_B_DESB800_1 (ESTROGEN RECEPTOR ALPHA)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 10	ALA A 151 GLU A 152 LEU A 183 LEU A 96 LEU A 112	None	1.48A	3erdB-5czzA: undetectable	3erdB-5czzA: 13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1101_1 (STRUCTURAL PROTEIN VP3)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	3 / 3	GLU A 729 ASP A 712 ASP A 722	None	0.73A	3jb2A-5czzA: 2.3	3jb2A-5czzA: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_S_TFPS202_1 (PROTEIN S100-A4)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 6	LEU A 660 SER A 662 PHE A 664 ILE A 436	None	1.02A	3ko0S-5czzA: undetectable	3ko0S-5czzA: 6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M0W_E_P77E203_1 (PROTEIN S100-A4)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	PHE A 36 SER A 453 LEU A 9 ASP A 10	None	0.98A	3m0wE-5czzA: undetectable 3m0wF-5czzA: undetectable 3m0wG-5czzA: undetectable 3m0wH-5czzA: undetectable	3m0wE-5czzA: 6.40 3m0wF-5czzA: 6.40 3m0wG-5czzA: 6.40 3m0wH-5czzA: 6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S56_A_ROCA201_2 (PROTEASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 9	LEU A 9 ASP A 648 GLY A 655 ILE A 474 ILE A 476	None	1.02A	3s56B-5czzA: undetectable	3s56B-5czzA: 7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SAN_A_ZMRA901_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.31A	3sanA-5czzA: undetectable	3sanA-5czzA: 15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SAN_B_ZMRB901_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.30A	3sanB-5czzA: undetectable	3sanB-5czzA: 15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_A_ZMRA1002_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.30A	3ticA-5czzA: undetectable	3ticA-5czzA: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_B_ZMRB1002_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.31A	3ticB-5czzA: undetectable	3ticB-5czzA: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_C_ZMRC1002_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.30A	3ticC-5czzA: undetectable	3ticC-5czzA: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TIC_D_ZMRD1002_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.31A	3ticD-5czzA: undetectable	3ticD-5czzA: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ6_A_SAMA300_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ILE A 676 GLY A 8 ILE A 21 ILE A 20 ASP A 10	None	1.04A	3uj6A-5czzA: undetectable	3uj6A-5czzA: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ7_A_SAMA301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ILE A 676 GLY A 8 ILE A 21 ILE A 20 ALA A 705	None	0.93A	3uj7A-5czzA: undetectable	3uj7A-5czzA: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH503_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	ARG A 209 TRP A 223 ARG A 59 GLY A 222	U B 64 ( 3.7A) None U B 16 ( 2.4A) None	0.92A	3v4tH-5czzA: undetectable	3v4tH-5czzA: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_A_ZPCA1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	ARG A 980 ILE A 982 ASN A 995 GLU A1006	None	1.01A	4a97E-5czzA: undetectable	4a97E-5czzA: 13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_D_ZPCD1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	ARG A 980 ILE A 982 ASN A 995 GLU A1006	None	1.05A	4a97C-5czzA: undetectable	4a97C-5czzA: 13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_E_ZPCE1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	ARG A 980 ILE A 982 ASN A 995 GLU A1006	None	1.02A	4a97D-5czzA: undetectable	4a97D-5czzA: 13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_H_ZPCH1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	ARG A 980 ILE A 982 ASN A 995 GLU A1006	None	1.07A	4a97G-5czzA: 3.0	4a97G-5czzA: 13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_J_ZPCJ1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 8	ARG A 980 ILE A 982 ASN A 995 GLU A1006	None	0.97A	4a97I-5czzA: undetectable	4a97I-5czzA: 13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPN_A_ZMRA700_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.37A	4cpnA-5czzA: undetectable	4cpnA-5czzA: 18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_A_ZMRA1471_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.34A	4cpzA-5czzA: undetectable	4cpzA-5czzA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_B_ZMRB1471_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.32A	4cpzB-5czzA: undetectable	4cpzB-5czzA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_C_ZMRC1470_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.34A	4cpzC-5czzA: undetectable	4cpzC-5czzA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_D_ZMRD1471_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.32A	4cpzD-5czzA: undetectable	4cpzD-5czzA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_F_ZMRF1470_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.32A	4cpzF-5czzA: undetectable	4cpzF-5czzA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_G_ZMRG1471_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.37A	4cpzG-5czzA: undetectable	4cpzG-5czzA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_H_ZMRH1470_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.35A	4cpzH-5czzA: undetectable	4cpzH-5czzA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7C_A_ACTA504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	3 / 3	ARG A 209 TRP A 223 GLY A 222	U B 64 ( 3.7A) None None	0.65A	4e7cA-5czzA: undetectable	4e7cA-5czzA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_A_ACTA303_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	3 / 3	TYR A 176 HIS A 111 ARG A 92	None A B 50 ( 3.9A) None	1.13A	4htfA-5czzA: undetectable	4htfA-5czzA: 13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWR_A_ZMRA513_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.34A	4mwrA-5czzA: undetectable	4mwrA-5czzA: 14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_C_IPHC101_0 (INSULIN)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 11	LEU A 183 LEU A 109 LEU A 100 HIS A 191 LEU A 76	None	1.11A	4p65C-5czzA: undetectable 4p65D-5czzA: undetectable 4p65J-5czzA: undetectable 4p65L-5czzA: undetectable	4p65C-5czzA: 2.01 4p65D-5czzA: 4.05 4p65J-5czzA: 4.05 4p65L-5czzA: 4.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_G_IPHG101_0 (INSULIN)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 11	LEU A 100 HIS A 191 LEU A 76 LEU A 183 LEU A 109	None	1.10A	4p65B-5czzA: undetectable 4p65D-5czzA: undetectable 4p65G-5czzA: undetectable 4p65H-5czzA: undetectable	4p65B-5czzA: 4.05 4p65D-5czzA: 4.05 4p65G-5czzA: 2.01 4p65H-5czzA: 4.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGF_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 6	THR A 512 THR A 511 HIS A 527 LEU A 547	None	0.87A	4pgfA-5czzA: undetectable	4pgfA-5czzA: 18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_1 (ADENOSINE KINASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	GLY A 679 GLY A 678 ASN A 677 ALA A 479 ASP A 648	None	1.18A	4ubeA-5czzA: undetectable	4ubeA-5czzA: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4URO_D_NOVD2000_1 (DNA GYRASE SUBUNIT B)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	GLU A 628 ARG A 630 ILE A 632 SER A 562 THR A 587	None	1.32A	4uroD-5czzA: undetectable	4uroD-5czzA: 12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA5_A_ZMRA501_1 (NEURAMINIDASE)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 12	ARG A 92 GLU A 179 ALA A 144 ASN A 141 TYR A 176	None	1.36A	4wa5A-5czzA: undetectable	4wa5A-5czzA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JH7_B_6K9B503_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA-2B CHAIN)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	LEU A 35 GLU A 38 ASN A 995 ILE A 982	None	0.83A	5jh7C-5czzA: undetectable	5jh7C-5czzA: 17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JNC_A_ACTA305_0 (CARBONIC ANHYDRASE 4)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 4	GLN A 298 VAL A 287 GLU A 302 ILE A 283	None	1.30A	5jncA-5czzA: undetectable	5jncA-5czzA: 12.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUD_A_ERMA2001_2 (5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	THR A 336 LEU A 355 LYS A 353 GLU A 366	None	1.13A	5tudA-5czzA: undetectable	5tudA-5czzA: 16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W97_C_CHDC302_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	LEU A 184 ASP A 199 THR A 200 HIS A 62	None None None G B 65 ( 4.2A)	1.22A	5w97C-5czzA: undetectable 5w97a-5czzA: 1.0 5w97c-5czzA: undetectable	5w97C-5czzA: 11.64 5w97a-5czzA: 18.66 5w97c-5czzA: 11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC303_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	LEU A 184 ASP A 199 THR A 200 HIS A 62	None None None G B 65 ( 4.2A)	1.21A	5wauC-5czzA: undetectable 5waua-5czzA: undetectable 5wauc-5czzA: undetectable	5wauC-5czzA: 11.64 5waua-5czzA: 18.66 5wauc-5czzA: 11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 5	ARG A 650 PHE A 444 PHE A 454 LEU A 478	None	1.21A	5wauC-5czzA: undetectable 5wauJ-5czzA: undetectable	5wauC-5czzA: 11.64 5wauJ-5czzA: 6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BSI_A_EFZA601_1 (REVERSE TRANSCRIPTASE P66 SUBUNIT)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	5 / 10	LEU A 205 LYS A 181 TYR A 176 LEU A 112 TYR A 201	None	1.43A	6bsiA-5czzA: 5.2	6bsiA-5czzA: 7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_D_EY4D500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 7	ILE A 13 VAL A 450 ALA A 652 THR A 653	None	0.85A	6cduC-5czzA: 3.4 6cduD-5czzA: 3.4	6cduC-5czzA: 14.47 6cduD-5czzA: 14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F88_A_STRA502_1 (CYTOCHROME P450 CYP260A1)	5czz	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Staphylococcus aureus)	4 / 6	PHE A 715 LEU A 721 ALA A 724 ASN A 567	None	0.82A	6f88A-5czzA: undetectable	6f88A-5czzA: 6.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4G_A_ZMRA466_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.33A","1a4gA-5czzA:undetectable","1a4gA-5czzA:16.85"],["1A4G_B_ZMRB466_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.33A","1a4gB-5czzA:undetectable","1a4gB-5czzA:16.85"],["1D0V_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"GLY A 222;PHE A 221;SER A 219;GLY A 214","None;  C B  15 ( 3.7A);  C B  67 ( 2.5A);  C B  15 ( 3.4A)","0.62A","1d0vA-5czzA:undetectable","1d0vA-5czzA:15.02"],["1FO4_B_SALB4005_1","XANTHINE DEHYDROGENASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"SER A 453;ARG A 774;PHE A  36;VAL A 449","None;  U B  72 ( 3.1A);None;None","1.09A","1fo4B-5czzA:2.8","1fo4B-5czzA:22.47"],["1KIJ_A_NOVA400_2","DNA GYRASE SUBUNIT B","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",3,"ASN A 968;PHE A 914;VAL A 981","None","0.78A","1kijA-5czzA:undetectable","1kijA-5czzA:17.53"],["1LIN_A_TFPA154_1","CALMODULIN","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"LEU A 112;GLU A 179;LEU A  96;GLU A 152","None","1.08A","1linA-5czzA:undetectable","1linA-5czzA:10.11"],["1NNC_A_ZMRA479_1","NEURAMINIDASE N9","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.32A","1nncA-5czzA:undetectable","1nncA-5czzA:14.95"],["1P33_C_MTXC353_1","PTERIDINE REDUCTASE 1","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"SER A 246;LEU A 355;TYR A 389;LEU A 371;LEU A 347","None","1.27A","1p33C-5czzA:undetectable","1p33C-5czzA:13.42"],["1RMT_B_ADNB1502_1","CLASS B ACID PHOSPHATASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"PHE A 197;LEU A  71;THR A 200;TYR A 201","None","1.08A","1rmtB-5czzA:undetectable","1rmtB-5czzA:11.52"],["1RMT_D_ADND1504_1","CLASS B ACID PHOSPHATASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"PHE A 197;LEU A  71;THR A 200;TYR A 201","None","1.12A","1rmtD-5czzA:undetectable","1rmtD-5czzA:11.52"],["1ZGY_A_BRLA503_2","PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ILE A 707;ILE A 753;ILE A 760;LEU A 646","None","0.89A","1zgyA-5czzA:undetectable","1zgyA-5czzA:13.91"],["2AZQ_A_PCFA954_0","CATECHOL 1,2-DIOXYGENASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A  70;HIS A 111;ALA A 113;GLU A 179;LEU A 183","None;  A B  50 ( 3.9A);None;None;None","1.42A","2azqA-5czzA:undetectable","2azqA-5czzA:14.27"],["2AZQ_A_PCFA954_0","CATECHOL 1,2-DIOXYGENASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A1035;HIS A 701;ALA A 702;LEU A 706;GLU A 477","None","1.10A","2azqA-5czzA:undetectable","2azqA-5czzA:14.27"],["2B60_B_RITB100_1","GAG-POL POLYPROTEIN;GAG-POL POLYPROTEIN","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  34;GLY A  19;ILE A 465;ILE A 476;ILE A 464","None","0.88A","2b60A-5czzA:undetectable","2b60A-5czzA:6.53"],["2CDQ_A_SAMA1500_0","ASPARTOKINASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ILE A 283;ARG A 269;LEU A 275;GLU A 279","None","0.89A","2cdqA-5czzA:1.9","2cdqA-5czzA:19.08"],["2CML_A_ZMRA1477_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.33A","2cmlA-5czzA:undetectable","2cmlA-5czzA:16.87"],["2CML_B_ZMRB2477_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.31A","2cmlB-5czzA:undetectable","2cmlB-5czzA:16.87"],["2CML_C_ZMRC3477_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.38A","2cmlC-5czzA:undetectable","2cmlC-5czzA:16.87"],["2CML_D_ZMRD4477_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.33A","2cmlD-5czzA:undetectable","2cmlD-5czzA:16.87"],["2JAP_A_J01A1249_1","CLAVALDEHYDE DEHYDROGENASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A 395;ILE A 417;ALA A 399;TYR A 239;TYR A 256","  A B   4 ( 4.6A);None;None;  A B   3 ( 4.8A);  A B   4 ( 4.4A)","1.18A","2japA-5czzA:2.3","2japA-5czzA:11.89"],["2JAP_B_J01B1249_1","CLAVALDEHYDE DEHYDROGENASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A 395;ILE A 417;ALA A 399;TYR A 239;TYR A 256","  A B   4 ( 4.6A);None;None;  A B   3 ( 4.8A);  A B   4 ( 4.4A)","1.22A","2japB-5czzA:3.0","2japB-5czzA:11.89"],["2JAP_C_J01C1249_1","CLAVALDEHYDE DEHYDROGENASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A 395;ILE A 417;ALA A 399;TYR A 239;TYR A 256","  A B   4 ( 4.6A);None;None;  A B   3 ( 4.8A);  A B   4 ( 4.4A)","1.17A","2japC-5czzA:2.4","2japC-5czzA:11.89"],["2JAP_D_J01D1249_1","CLAVALDEHYDE DEHYDROGENASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A 395;ILE A 417;ALA A 399;TYR A 239;TYR A 256","  A B   4 ( 4.6A);None;None;  A B   3 ( 4.8A);  A B   4 ( 4.4A)","1.19A","2japD-5czzA:3.1","2japD-5czzA:11.89"],["2NNH_A_9CRA502_1","CYTOCHROME P450 2C8","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"SER A 457;ILE A 461;LEU A   7;VAL A 673;ILE A 708","None","1.03A","2nnhA-5czzA:1.5","2nnhA-5czzA:19.11"],["2O01_A_PQNA5001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"PHE A 454;SER A 457;ALA A 479;LEU A 478","None","1.07A","2o01A-5czzA:undetectable","2o01A-5czzA:20.02"],["2O4K_A_DR7A301_1","PROTEASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"GLY A  19;GLY A   8;ILE A 475;PRO A 471;ILE A 461","None","1.08A","2o4kA-5czzA:undetectable","2o4kA-5czzA:6.63"],["3ERD_B_DESB800_1","ESTROGEN RECEPTOR ALPHA","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ALA A 151;GLU A 152;LEU A 183;LEU A  96;LEU A 112","None","1.48A","3erdB-5czzA:undetectable","3erdB-5czzA:13.51"],["3JB2_A_SAMA1101_1","STRUCTURAL PROTEIN VP3","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",3,"GLU A 729;ASP A 712;ASP A 722","None","0.73A","3jb2A-5czzA:2.3","3jb2A-5czzA:22.10"],["3KO0_S_TFPS202_1","PROTEIN S100-A4","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"LEU A 660;SER A 662;PHE A 664;ILE A 436","None","1.02A","3ko0S-5czzA:undetectable","3ko0S-5czzA:6.32"],["3M0W_E_P77E203_1","PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"PHE A  36;SER A 453;LEU A   9;ASP A  10","None","0.98A","3m0wE-5czzA:undetectable;3m0wF-5czzA:undetectable;3m0wG-5czzA:undetectable;3m0wH-5czzA:undetectable","3m0wE-5czzA:6.40;3m0wF-5czzA:6.40;3m0wG-5czzA:6.40;3m0wH-5czzA:6.40"],["3S56_A_ROCA201_2","PROTEASE;PROTEASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A   9;ASP A 648;GLY A 655;ILE A 474;ILE A 476","None","1.02A","3s56B-5czzA:undetectable","3s56B-5czzA:7.46"],["3SAN_A_ZMRA901_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.31A","3sanA-5czzA:undetectable","3sanA-5czzA:15.40"],["3SAN_B_ZMRB901_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.30A","3sanB-5czzA:undetectable","3sanB-5czzA:15.40"],["3TIC_A_ZMRA1002_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.30A","3ticA-5czzA:undetectable","3ticA-5czzA:16.25"],["3TIC_B_ZMRB1002_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.31A","3ticB-5czzA:undetectable","3ticB-5czzA:16.25"],["3TIC_C_ZMRC1002_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.30A","3ticC-5czzA:undetectable","3ticC-5czzA:16.25"],["3TIC_D_ZMRD1002_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.31A","3ticD-5czzA:undetectable","3ticD-5czzA:16.25"],["3UJ6_A_SAMA300_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ILE A 676;GLY A   8;ILE A  21;ILE A  20;ASP A  10","None","1.04A","3uj6A-5czzA:undetectable","3uj6A-5czzA:14.19"],["3UJ7_A_SAMA301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ILE A 676;GLY A   8;ILE A  21;ILE A  20;ALA A 705","None","0.93A","3uj7A-5czzA:undetectable","3uj7A-5czzA:14.19"],["3V4T_H_ACTH503_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ARG A 209;TRP A 223;ARG A  59;GLY A 222","  U B  64 ( 3.7A);None;  U B  16 ( 2.4A);None","0.92A","3v4tH-5czzA:undetectable","3v4tH-5czzA:17.83"],["4A97_A_ZPCA1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ARG A 980;ILE A 982;ASN A 995;GLU A1006","None","1.01A","4a97E-5czzA:undetectable","4a97E-5czzA:13.78"],["4A97_D_ZPCD1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ARG A 980;ILE A 982;ASN A 995;GLU A1006","None","1.05A","4a97C-5czzA:undetectable","4a97C-5czzA:13.78"],["4A97_E_ZPCE1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ARG A 980;ILE A 982;ASN A 995;GLU A1006","None","1.02A","4a97D-5czzA:undetectable","4a97D-5czzA:13.78"],["4A97_H_ZPCH1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ARG A 980;ILE A 982;ASN A 995;GLU A1006","None","1.07A","4a97G-5czzA:3.0","4a97G-5czzA:13.78"],["4A97_J_ZPCJ1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ARG A 980;ILE A 982;ASN A 995;GLU A1006","None","0.97A","4a97I-5czzA:undetectable","4a97I-5czzA:13.78"],["4CPN_A_ZMRA700_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.37A","4cpnA-5czzA:undetectable","4cpnA-5czzA:18.37"],["4CPZ_A_ZMRA1471_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.34A","4cpzA-5czzA:undetectable","4cpzA-5czzA:18.15"],["4CPZ_B_ZMRB1471_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.32A","4cpzB-5czzA:undetectable","4cpzB-5czzA:18.15"],["4CPZ_C_ZMRC1470_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.34A","4cpzC-5czzA:undetectable","4cpzC-5czzA:18.15"],["4CPZ_D_ZMRD1471_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.32A","4cpzD-5czzA:undetectable","4cpzD-5czzA:18.15"],["4CPZ_F_ZMRF1470_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.32A","4cpzF-5czzA:undetectable","4cpzF-5czzA:18.15"],["4CPZ_G_ZMRG1471_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.37A","4cpzG-5czzA:undetectable","4cpzG-5czzA:18.15"],["4CPZ_H_ZMRH1470_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.35A","4cpzH-5czzA:undetectable","4cpzH-5czzA:18.15"],["4E7C_A_ACTA504_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",3,"ARG A 209;TRP A 223;GLY A 222","  U B  64 ( 3.7A);None;None","0.65A","4e7cA-5czzA:undetectable","4e7cA-5czzA:17.75"],["4HTF_A_ACTA303_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",3,"TYR A 176;HIS A 111;ARG A  92","None;  A B  50 ( 3.9A);None","1.13A","4htfA-5czzA:undetectable","4htfA-5czzA:13.16"],["4MWR_A_ZMRA513_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.34A","4mwrA-5czzA:undetectable","4mwrA-5czzA:14.95"],["4P65_C_IPHC101_0","INSULIN","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A 183;LEU A 109;LEU A 100;HIS A 191;LEU A  76","None","1.11A","4p65C-5czzA:undetectable;4p65D-5czzA:undetectable;4p65J-5czzA:undetectable;4p65L-5czzA:undetectable","4p65C-5czzA:2.01;4p65D-5czzA:4.05;4p65J-5czzA:4.05;4p65L-5czzA:4.05"],["4P65_G_IPHG101_0","INSULIN","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A 100;HIS A 191;LEU A  76;LEU A 183;LEU A 109","None","1.10A","4p65B-5czzA:undetectable;4p65D-5czzA:undetectable;4p65G-5czzA:undetectable;4p65H-5czzA:undetectable","4p65B-5czzA:4.05;4p65D-5czzA:4.05;4p65G-5czzA:2.01;4p65H-5czzA:4.05"],["4PGF_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"THR A 512;THR A 511;HIS A 527;LEU A 547","None","0.87A","4pgfA-5czzA:undetectable","4pgfA-5czzA:18.71"],["4UBE_A_2FAA401_1","ADENOSINE KINASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"GLY A 679;GLY A 678;ASN A 677;ALA A 479;ASP A 648","None","1.18A","4ubeA-5czzA:undetectable","4ubeA-5czzA:15.09"],["4URO_D_NOVD2000_1","DNA GYRASE SUBUNIT B","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"GLU A 628;ARG A 630;ILE A 632;SER A 562;THR A 587","None","1.32A","4uroD-5czzA:undetectable","4uroD-5czzA:12.63"],["4WA5_A_ZMRA501_1","NEURAMINIDASE","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"ARG A  92;GLU A 179;ALA A 144;ASN A 141;TYR A 176","None","1.36A","4wa5A-5czzA:undetectable","4wa5A-5czzA:14.96"],["5JH7_B_6K9B503_1","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"LEU A  35;GLU A  38;ASN A 995;ILE A 982","None","0.83A","5jh7C-5czzA:undetectable","5jh7C-5czzA:17.88"],["5JNC_A_ACTA305_0","CARBONIC ANHYDRASE 4","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"GLN A 298;VAL A 287;GLU A 302;ILE A 283","None","1.30A","5jncA-5czzA:undetectable","5jncA-5czzA:12.51"],["5TUD_A_ERMA2001_2","5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"THR A 336;LEU A 355;LYS A 353;GLU A 366","None","1.13A","5tudA-5czzA:undetectable","5tudA-5czzA:16.57"],["5W97_C_CHDC302_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"LEU A 184;ASP A 199;THR A 200;HIS A  62","None;None;None;  G B  65 ( 4.2A)","1.22A","5w97C-5czzA:undetectable;5w97a-5czzA:1.0;5w97c-5czzA:undetectable","5w97C-5czzA:11.64;5w97a-5czzA:18.66;5w97c-5czzA:11.64"],["5WAU_C_CHDC303_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"LEU A 184;ASP A 199;THR A 200;HIS A  62","None;None;None;  G B  65 ( 4.2A)","1.21A","5wauC-5czzA:undetectable;5waua-5czzA:undetectable;5wauc-5czzA:undetectable","5wauC-5czzA:11.64;5waua-5czzA:18.66;5wauc-5czzA:11.64"],["5WAU_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ARG A 650;PHE A 444;PHE A 454;LEU A 478","None","1.21A","5wauC-5czzA:undetectable;5wauJ-5czzA:undetectable","5wauC-5czzA:11.64;5wauJ-5czzA:6.06"],["6BSI_A_EFZA601_1","REVERSE TRANSCRIPTASE P66 SUBUNIT","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",5,"LEU A 205;LYS A 181;TYR A 176;LEU A 112;TYR A 201","None","1.43A","6bsiA-5czzA:5.2","6bsiA-5czzA:7.52"],["6CDU_D_EY4D500_0","CHIMERIC ALPHA1GABAA RECEPTOR","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"ILE A  13;VAL A 450;ALA A 652;THR A 653","None","0.85A","6cduC-5czzA:3.4;6cduD-5czzA:3.4","6cduC-5czzA:14.47;6cduD-5czzA:14.47"],["6F88_A_STRA502_1","CYTOCHROME P450 CYP260A1","5czz","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","Staphylococcus aureus",4,"PHE A 715;LEU A 721;ALA A 724;ASN A 567","None","0.82A","6f88A-5czzA:undetectable","6f88A-5czzA:6.47"]]