SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C6Z_B_ROCB505_2 (PROTEIN (PROTEASE))	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.02A	1c6zB-5d01A: undetectable	1c6zB-5d01A: 12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4Y_A_TPVA501_1 (PROTEIN (HIV-1 PROTEASE))	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 10	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.13A	1d4yA-5d01A: undetectable	1d4yA-5d01A: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK2_A_T44A3003_1 (SERUM ALBUMIN)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	4 / 6	PHE A 221 ILE A 203 LYS A 200 ALA A 230	None	1.24A	1hk2A-5d01A: undetectable	1hk2A-5d01A: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK3_A_T44A3003_1 (SERUM ALBUMIN)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	3 / 4	LYS A 241 ALA A 244 MET A 259	None	0.73A	1hk3A-5d01A: undetectable	1hk3A-5d01A: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KYV_B_RBFB502_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ILE A 116 HIS A 99 GLY A 7 LEU A 24 HIS A 94	None	1.47A	1kyvA-5d01A: 5.2 1kyvB-5d01A: 5.1	1kyvA-5d01A: 19.05 1kyvB-5d01A: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_A_RBFA300_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	GLY A 7 LEU A 24 HIS A 94 ILE A 116 HIS A 99	None	1.43A	2a58A-5d01A: 5.0 2a58E-5d01A: 5.0	2a58A-5d01A: 19.05 2a58E-5d01A: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_D_RBFD303_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ILE A 116 HIS A 99 GLY A 7 LEU A 24 HIS A 94	None	1.42A	2a58C-5d01A: 5.2 2a58D-5d01A: 3.9	2a58C-5d01A: 19.05 2a58D-5d01A: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AQU_B_DR7B300_2 (HIV-1 PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	6 / 11	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.32A	2aquB-5d01A: undetectable	2aquB-5d01A: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FXE_A_DR7A102_2 (POL PROTEIN)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	6 / 11	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.31A	2fxeB-5d01A: undetectable	2fxeB-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G78_A_REAA200_1 (CELLULAR RETINOIC ACID-BINDING PROTEIN 2)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	LEU A 28 ILE A 90 THR A 119 VAL A 117 VAL A 363	None	1.11A	2g78A-5d01A: undetectable	2g78A-5d01A: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NMY_A_ROCA401_1 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	6 / 12	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.31A	2nmyA-5d01A: undetectable	2nmyA-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNP_A_ROCA401_2 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.05A	2nnpB-5d01A: undetectable	2nnpB-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4K_A_DR7A301_1 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.05A	2o4kA-5d01A: undetectable	2o4kA-5d01A: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4P_A_TPVA300_1 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.11A	2o4pA-5d01A: undetectable	2o4pA-5d01A: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YJA_B_ESTB1550_1 (ESTROGEN RECEPTOR)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ALA A 141 LEU A 97 ILE A 125 GLY A 122 LEU A 120	None None None GMT A 401 ( 4.0A) None	1.22A	2yjaB-5d01A: undetectable	2yjaB-5d01A: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_A_ADNA500_2 (ADENOSYLHOMOCYSTEINA SE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	4 / 5	GLN A 368 THR A 119 HIS A 94 LEU A 24	None	1.34A	3ce6A-5d01A: 4.3	3ce6A-5d01A: 23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_C_ADNC500_2 (ADENOSYLHOMOCYSTEINA SE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	4 / 5	GLN A 368 THR A 119 HIS A 94 LEU A 24	None	1.33A	3ce6C-5d01A: 4.3	3ce6C-5d01A: 23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKW_B_DR7B100_1 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	6 / 10	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.32A	3ekwA-5d01A: undetectable	3ekwA-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL4_A_ROCA100_2 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 9	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.02A	3el4B-5d01A: undetectable	3el4B-5d01A: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6P_B_TA1B502_1 (TUBULIN BETA CHAIN)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	VAL A 288 GLU A 283 LEU A 232 GLY A 301 LEU A 279	None GMT A 401 (-3.6A) None None None	1.16A	3j6pB-5d01A: undetectable	3j6pB-5d01A: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDW_A_RITA100_2 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	6 / 9	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.28A	3ndwB-5d01A: undetectable	3ndwB-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDX_A_RITA100_1 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.04A	3ndxA-5d01A: undetectable	3ndxA-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDX_A_RITA100_2 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	6 / 11	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.30A	3ndxB-5d01A: undetectable	3ndxB-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PMZ_E_TUBE220_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	4 / 6	GLN A 365 ILE A 362 SER A 153 SER A 152	None	1.17A	3pmzD-5d01A: undetectable	3pmzD-5d01A: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_A_TPVA100_1 (HIV-1 PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.13A	3spkA-5d01A: undetectable	3spkA-5d01A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_B_ROCB801_2 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.02A	3tkgB-5d01A: undetectable	3tkgB-5d01A: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_2 (PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	0.97A	3tkgD-5d01A: undetectable	3tkgD-5d01A: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U7S_A_017A201_2 (POL POLYPROTEIN)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 9	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.14A	3u7sB-5d01A: undetectable	3u7sB-5d01A: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PXM_B_ESTB2000_1 (ESTROGEN RECEPTOR)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ALA A 141 LEU A 97 ILE A 125 GLY A 122 LEU A 120	None None None GMT A 401 ( 4.0A) None	1.21A	4pxmB-5d01A: undetectable	4pxmB-5d01A: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE5_A_OBNA1104_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	GLU A 339 ASP A 274 GLY A 296 ALA A 292 ILE A 203	None	1.24A	4xe5A-5d01A: 4.4	4xe5A-5d01A: 17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_1 (ESTROGEN RECEPTOR)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ALA A 141 LEU A 97 ILE A 125 GLY A 122 LEU A 120	None None None GMT A 401 ( 4.0A) None	1.02A	4xi3B-5d01A: undetectable	4xi3B-5d01A: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXB_B_ESTB601_1 (ESTROGEN RECEPTOR)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ALA A 141 LEU A 97 ILE A 125 GLY A 122 LEU A 120	None None None GMT A 401 ( 4.0A) None	1.20A	5dxbB-5d01A: undetectable	5dxbB-5d01A: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGZ_A_SPRA404_2 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 9	LEU A 290 ILE A 307 PHE A 285 VAL A 151 GLU A 356	None None None GMT A 401 (-4.3A) None	1.44A	5igzA-5d01A: undetectable	5igzA-5d01A: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR0_A_478A101_1 (PROTEASE E35D-APV)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 9	ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.14A	5kr0A-5d01A: undetectable	5kr0A-5d01A: 13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR1_B_017B101_1 (PROTEASE PR5-DRV)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 10	ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.06A	5kr1A-5d01A: undetectable	5kr1A-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR2_A_ROCA101_2 (PROTEASE PR5-SQV)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 11	ALA A 93 ILE A 79 GLY A 7 ILE A 6 ILE A 116	None	1.12A	5kr2B-5d01A: undetectable	5kr2B-5d01A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OGC_B_TA1B601_1 (TUBULIN BETA CHAIN)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	VAL A 288 GLU A 283 LEU A 232 GLY A 301 LEU A 279	None GMT A 401 (-3.6A) None None None	0.98A	5ogcB-5d01A: 3.1	5ogcB-5d01A: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VNC_C_GCSC801_1 (GLYCOGEN [STARCH] SYNTHASE ISOFORM 2)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	7 / 10	GLY A 16 HIS A 121 VAL A 151 ASN A 174 LYS A 212 GLU A 283 GLY A 286	GMT A 401 (-3.4A) GMT A 401 (-3.8A) GMT A 401 (-4.3A) GMT A 401 (-3.4A) GMT A 401 ( 4.4A) GMT A 401 (-3.6A) GMT A 401 (-3.7A)	0.41A	5vncC-5d01A: 12.0	5vncC-5d01A: 11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DIF_B_TPVB201_0 (HIV-1 PROTEASE)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ARG A 147 ALA A 93 ILE A 79 GLY A 7 ILE A 6	None	1.11A	6difA-5d01A: undetectable	6difA-5d01A: 11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_1 (TUBULIN BETA CHAIN)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	ASP A 161 GLU A 158 ASP A 136 LEU A 97 LEU A 120	None	1.24A	6ew0F-5d01A: undetectable	6ew0F-5d01A: 13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_A_ADNA501_2 (-)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	4 / 5	GLN A 368 THR A 119 HIS A 94 LEU A 24	None	1.39A	6gbnA-5d01A: 5.7	6gbnA-5d01A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_D_ADND501_2 (-)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	4 / 5	GLN A 368 THR A 119 HIS A 94 LEU A 24	None	1.40A	6gbnD-5d01A: 5.9	6gbnD-5d01A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNE_A_ACRA602_1 (-)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	GLY A 15 GLY A 16 VAL A 151 ASN A 174 GLY A 286	GMT A 401 ( 4.7A) GMT A 401 (-3.4A) GMT A 401 (-4.3A) GMT A 401 (-3.4A) GMT A 401 (-3.7A)	0.48A	6gneA-5d01A: 30.1	6gneA-5d01A: 26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNE_B_ACRB602_1 (-)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	GLY A 15 GLY A 16 VAL A 151 ASN A 174 GLY A 286	GMT A 401 ( 4.7A) GMT A 401 (-3.4A) GMT A 401 (-4.3A) GMT A 401 (-3.4A) GMT A 401 (-3.7A)	0.47A	6gneB-5d01A: 30.0	6gneB-5d01A: 26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNG_A_QPSA601_2 (-)	5d01	N-ACETYL-ALPHA-D-GLU COSAMINYL L-MALATE SYNTHASE (Bacillus subtilis)	5 / 12	GLY A 16 HIS A 121 VAL A 151 GLU A 283 GLY A 286	GMT A 401 (-3.4A) GMT A 401 (-3.8A) GMT A 401 (-4.3A) GMT A 401 (-3.6A) GMT A 401 (-3.7A)	0.43A	6gngA-5d01A: 28.6	6gngA-5d01A: 22.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C6Z_B_ROCB505_2","PROTEIN (PROTEASE)","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.02A","1c6zB-5d01A:undetectable","1c6zB-5d01A:12.20"],["1D4Y_A_TPVA501_1","PROTEIN (HIV-1 PROTEASE)","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.13A","1d4yA-5d01A:undetectable","1d4yA-5d01A:13.79"],["1HK2_A_T44A3003_1","SERUM ALBUMIN","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",4,"PHE A 221;ILE A 203;LYS A 200;ALA A 230","None","1.24A","1hk2A-5d01A:undetectable","1hk2A-5d01A:20.27"],["1HK3_A_T44A3003_1","SERUM ALBUMIN","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",3,"LYS A 241;ALA A 244;MET A 259","None","0.73A","1hk3A-5d01A:undetectable","1hk3A-5d01A:20.27"],["1KYV_B_RBFB502_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ILE A 116;HIS A  99;GLY A   7;LEU A  24;HIS A  94","None","1.47A","1kyvA-5d01A:5.2;1kyvB-5d01A:5.1","1kyvA-5d01A:19.05;1kyvB-5d01A:19.05"],["2A58_A_RBFA300_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"GLY A   7;LEU A  24;HIS A  94;ILE A 116;HIS A  99","None","1.43A","2a58A-5d01A:5.0;2a58E-5d01A:5.0","2a58A-5d01A:19.05;2a58E-5d01A:19.05"],["2A58_D_RBFD303_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ILE A 116;HIS A  99;GLY A   7;LEU A  24;HIS A  94","None","1.42A","2a58C-5d01A:5.2;2a58D-5d01A:3.9","2a58C-5d01A:19.05;2a58D-5d01A:19.05"],["2AQU_B_DR7B300_2","HIV-1 PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",6,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.32A","2aquB-5d01A:undetectable","2aquB-5d01A:13.79"],["2FXE_A_DR7A102_2","POL PROTEIN;POL PROTEIN","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",6,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.31A","2fxeB-5d01A:undetectable","2fxeB-5d01A:14.06"],["2G78_A_REAA200_1","CELLULAR RETINOIC ACID-BINDING PROTEIN 2","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"LEU A  28;ILE A  90;THR A 119;VAL A 117;VAL A 363","None","1.11A","2g78A-5d01A:undetectable","2g78A-5d01A:15.30"],["2NMY_A_ROCA401_1","PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",6,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.31A","2nmyA-5d01A:undetectable","2nmyA-5d01A:14.06"],["2NNP_A_ROCA401_2","PROTEASE;PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.05A","2nnpB-5d01A:undetectable","2nnpB-5d01A:14.06"],["2O4K_A_DR7A301_1","PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.05A","2o4kA-5d01A:undetectable","2o4kA-5d01A:13.79"],["2O4P_A_TPVA300_1","PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.11A","2o4pA-5d01A:undetectable","2o4pA-5d01A:13.79"],["2YJA_B_ESTB1550_1","ESTROGEN RECEPTOR","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A 141;LEU A  97;ILE A 125;GLY A 122;LEU A 120","None;None;None;GMT A 401 ( 4.0A);None","1.22A","2yjaB-5d01A:undetectable","2yjaB-5d01A:21.71"],["3CE6_A_ADNA500_2","ADENOSYLHOMOCYSTEINASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",4,"GLN A 368;THR A 119;HIS A  94;LEU A  24","None","1.34A","3ce6A-5d01A:4.3","3ce6A-5d01A:23.43"],["3CE6_C_ADNC500_2","ADENOSYLHOMOCYSTEINASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",4,"GLN A 368;THR A 119;HIS A  94;LEU A  24","None","1.33A","3ce6C-5d01A:4.3","3ce6C-5d01A:23.43"],["3EKW_B_DR7B100_1","PROTEASE;PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",6,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.32A","3ekwA-5d01A:undetectable","3ekwA-5d01A:14.06"],["3EL4_A_ROCA100_2","PROTEASE;PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.02A","3el4B-5d01A:undetectable","3el4B-5d01A:13.26"],["3J6P_B_TA1B502_1","TUBULIN BETA CHAIN","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"VAL A 288;GLU A 283;LEU A 232;GLY A 301;LEU A 279","None;GMT A 401 (-3.6A);None;None;None","1.16A","3j6pB-5d01A:undetectable","3j6pB-5d01A:24.57"],["3NDW_A_RITA100_2","PROTEASE;PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",6,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.28A","3ndwB-5d01A:undetectable","3ndwB-5d01A:14.06"],["3NDX_A_RITA100_1","PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.04A","3ndxA-5d01A:undetectable","3ndxA-5d01A:14.06"],["3NDX_A_RITA100_2","PROTEASE;PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",6,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.30A","3ndxB-5d01A:undetectable","3ndxB-5d01A:14.06"],["3PMZ_E_TUBE220_1","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",4,"GLN A 365;ILE A 362;SER A 153;SER A 152","None","1.17A","3pmzD-5d01A:undetectable","3pmzD-5d01A:19.42"],["3SPK_A_TPVA100_1","HIV-1 PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.13A","3spkA-5d01A:undetectable","3spkA-5d01A:16.31"],["3TKG_B_ROCB801_2","PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.02A","3tkgB-5d01A:undetectable","3tkgB-5d01A:16.42"],["3TKG_C_ROCC901_2","PROTEASE;PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","0.97A","3tkgD-5d01A:undetectable","3tkgD-5d01A:16.42"],["3U7S_A_017A201_2","POL POLYPROTEIN;POL POLYPROTEIN","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.14A","3u7sB-5d01A:undetectable","3u7sB-5d01A:13.26"],["4PXM_B_ESTB2000_1","ESTROGEN RECEPTOR","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A 141;LEU A  97;ILE A 125;GLY A 122;LEU A 120","None;None;None;GMT A 401 ( 4.0A);None","1.21A","4pxmB-5d01A:undetectable","4pxmB-5d01A:20.25"],["4XE5_A_OBNA1104_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"GLU A 339;ASP A 274;GLY A 296;ALA A 292;ILE A 203","None","1.24A","4xe5A-5d01A:4.4","4xe5A-5d01A:17.40"],["4XI3_B_29SB601_1","ESTROGEN RECEPTOR","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A 141;LEU A  97;ILE A 125;GLY A 122;LEU A 120","None;None;None;GMT A 401 ( 4.0A);None","1.02A","4xi3B-5d01A:undetectable","4xi3B-5d01A:21.15"],["5DXB_B_ESTB601_1","ESTROGEN RECEPTOR","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A 141;LEU A  97;ILE A 125;GLY A 122;LEU A 120","None;None;None;GMT A 401 ( 4.0A);None","1.20A","5dxbB-5d01A:undetectable","5dxbB-5d01A:20.96"],["5IGZ_A_SPRA404_2","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"LEU A 290;ILE A 307;PHE A 285;VAL A 151;GLU A 356","None;None;None;GMT A 401 (-4.3A);None","1.44A","5igzA-5d01A:undetectable","5igzA-5d01A:23.06"],["5KR0_A_478A101_1","PROTEASE E35D-APV","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.14A","5kr0A-5d01A:undetectable","5kr0A-5d01A:13.53"],["5KR1_B_017B101_1","PROTEASE PR5-DRV;PROTEASE PR5-DRV","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.06A","5kr1A-5d01A:undetectable","5kr1A-5d01A:14.06"],["5KR2_A_ROCA101_2","PROTEASE PR5-SQV;PROTEASE PR5-SQV","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ALA A  93;ILE A  79;GLY A   7;ILE A   6;ILE A 116","None","1.12A","5kr2B-5d01A:undetectable","5kr2B-5d01A:14.06"],["5OGC_B_TA1B601_1","TUBULIN BETA CHAIN","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"VAL A 288;GLU A 283;LEU A 232;GLY A 301;LEU A 279","None;GMT A 401 (-3.6A);None;None;None","0.98A","5ogcB-5d01A:3.1","5ogcB-5d01A:24.57"],["5VNC_C_GCSC801_1","GLYCOGEN [STARCH] SYNTHASE ISOFORM 2","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",7,"GLY A  16;HIS A 121;VAL A 151;ASN A 174;LYS A 212;GLU A 283;GLY A 286","GMT A 401 (-3.4A);GMT A 401 (-3.8A);GMT A 401 (-4.3A);GMT A 401 (-3.4A);GMT A 401 ( 4.4A);GMT A 401 (-3.6A);GMT A 401 (-3.7A)","0.41A","5vncC-5d01A:12.0","5vncC-5d01A:11.01"],["6DIF_B_TPVB201_0","HIV-1 PROTEASE","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ARG A 147;ALA A  93;ILE A  79;GLY A   7;ILE A   6","None","1.11A","6difA-5d01A:undetectable","6difA-5d01A:11.87"],["6EW0_F_TA1F502_1","TUBULIN BETA CHAIN","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"ASP A 161;GLU A 158;ASP A 136;LEU A  97;LEU A 120","None","1.24A","6ew0F-5d01A:undetectable","6ew0F-5d01A:13.03"],["6GBN_A_ADNA501_2","-","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",4,"GLN A 368;THR A 119;HIS A  94;LEU A  24","None","1.39A","6gbnA-5d01A:5.7","6gbnA-5d01A:22.78"],["6GBN_D_ADND501_2","-","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",4,"GLN A 368;THR A 119;HIS A  94;LEU A  24","None","1.40A","6gbnD-5d01A:5.9","6gbnD-5d01A:22.78"],["6GNE_A_ACRA602_1","-","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"GLY A  15;GLY A  16;VAL A 151;ASN A 174;GLY A 286","GMT A 401 ( 4.7A);GMT A 401 (-3.4A);GMT A 401 (-4.3A);GMT A 401 (-3.4A);GMT A 401 (-3.7A)","0.48A","6gneA-5d01A:30.1","6gneA-5d01A:26.01"],["6GNE_B_ACRB602_1","-","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"GLY A  15;GLY A  16;VAL A 151;ASN A 174;GLY A 286","GMT A 401 ( 4.7A);GMT A 401 (-3.4A);GMT A 401 (-4.3A);GMT A 401 (-3.4A);GMT A 401 (-3.7A)","0.47A","6gneB-5d01A:30.0","6gneB-5d01A:26.01"],["6GNG_A_QPSA601_2","-","5d01","N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE SYNTHASE","Bacillus subtilis",5,"GLY A  16;HIS A 121;VAL A 151;GLU A 283;GLY A 286","GMT A 401 (-3.4A);GMT A 401 (-3.8A);GMT A 401 (-4.3A);GMT A 401 (-3.6A);GMT A 401 (-3.7A)","0.43A","6gngA-5d01A:28.6","6gngA-5d01A:22.50"]]