SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 10 GLY C 180
ALA C 205
HIS C 210
THR C 225
ALA C 204
 None
 1.32A 1gtnO-5d04C:
undetectable
1gtnP-5d04C:
undetectable		 1gtnO-5d04C:
13.33
1gtnP-5d04C:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 7 GLU C  88
LEU C  56
VAL C 301
LEU C 335
 None
 1.01A 1hk3A-5d04C:
undetectable		 1hk3A-5d04C:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		3 / 3 ARG C 349
ASP C 286
ASN C 272
 None
 0.96A 1nbhA-5d04C:
undetectable		 1nbhA-5d04C:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		3 / 3 ARG C 349
ASP C 286
ASN C 272
 None
 0.94A 1nbhD-5d04C:
undetectable		 1nbhD-5d04C:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 10 GLU C 145
ILE C 234
GLY C 186
ILE C  59
MET C 302
 None
None
None
None
CL  C 404 ( 3.9A)
 1.41A 3adsA-5d04C:
undetectable		 3adsA-5d04C:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 VAL C 303
SER C 269
VAL C 283
ALA C 284
LEU C 336
 None
 1.03A 3hs6A-5d04C:
undetectable		 3hs6A-5d04C:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 ILE C  60
ILE C 234
ASP C 267
MET C 299
LEU C  57
 None
 1.16A 4a81A-5d04C:
undetectable		 4a81A-5d04C:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 ALA C 251
VAL C 248
ILE C 266
ASN C 272
HIS C 232
 None
 1.29A 4c49A-5d04C:
undetectable		 4c49A-5d04C:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 8 SER C 143
ILE C  59
LEU C  78
ILE C  91
 None
 0.94A 4dtaB-5d04C:
undetectable		 4dtaB-5d04C:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 ARG C 175
GLY C 203
ALA C 204
SER C 206
GLY C 227
 CL  C 402 (-2.9A)
None
None
None
None
 1.07A 4e1gB-5d04C:
undetectable		 4e1gB-5d04C:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 9 ALA C 252
ALA C 258
GLY C 259
ILE C 202
ILE C 199
 None
 1.14A 4eatB-5d04C:
undetectable		 4eatB-5d04C:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 LEU C 291
ARG C 346
VAL C  58
LEU C  89
ARG C  55
 None
None
None
None
EDO  C 408 (-3.5A)
 1.48A 4po0A-5d04C:
undetectable		 4po0A-5d04C:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.15A 4qvpH-5d04C:
undetectable
4qvpI-5d04C:
undetectable		 4qvpH-5d04C:
22.35
4qvpI-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.15A 4qvpV-5d04C:
undetectable
4qvpW-5d04C:
undetectable		 4qvpV-5d04C:
22.35
4qvpW-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 11 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.11A 4qvvH-5d04C:
undetectable		 4qvvH-5d04C:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 11 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.11A 4qvvV-5d04C:
undetectable		 4qvvV-5d04C:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 11 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.13A 4qvyH-5d04C:
undetectable		 4qvyH-5d04C:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.13A 4qvyV-5d04C:
undetectable
4qvyW-5d04C:
undetectable		 4qvyV-5d04C:
22.35
4qvyW-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 11 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.13A 4qw0H-5d04C:
undetectable
4qw0I-5d04C:
undetectable		 4qw0H-5d04C:
22.35
4qw0I-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 11 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.13A 4qw0V-5d04C:
undetectable
4qw0W-5d04C:
undetectable		 4qw0V-5d04C:
22.35
4qw0W-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.11A 4qw1H-5d04C:
undetectable
4qw1I-5d04C:
undetectable		 4qw1H-5d04C:
22.35
4qw1I-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.11A 4qw1V-5d04C:
undetectable
4qw1W-5d04C:
undetectable		 4qw1V-5d04C:
22.35
4qw1W-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		3 / 3 VAL C 260
PHE C 187
ARG C 175
 None
None
CL  C 402 (-2.9A)
 0.68A 4xr4B-5d04C:
undetectable		 4xr4B-5d04C:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.14A 5cz7V-5d04C:
undetectable
5cz7W-5d04C:
undetectable		 5cz7V-5d04C:
22.35
5cz7W-5d04C:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 11 GLN C 254
ALA C 166
GLY C 190
ALA C 198
THR C 169
 None
CL  C 403 ( 4.7A)
None
None
None
 1.13A 5d0xV-5d04C:
undetectable		 5d0xV-5d04C:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 GLY C 203
GLY C 226
THR C 225
HIS C 210
GLU C 176
 None
 0.99A 5njvD-5d04C:
undetectable		 5njvD-5d04C:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		3 / 3 ASP C 262
ASN C 297
ASP C 294
 None
 0.83A 5vopA-5d04C:
10.4		 5vopA-5d04C:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Neisseria
meningitidis) 		3 / 3 ASP C 262
ASN C 297
ASP C 294
 None
 0.87A 5vopB-5d04C:
3.9		 5vopB-5d04C:
22.95