SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 11 GLU A 375
VAL A 319
ILE A 318
LEU A 284
LEU A 328
 None
 1.22A 1mrqA-5d0nA:
undetectable		 1mrqA-5d0nA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 12 THR A 272
ILE A 289
LEU A 306
ALA A 403
LEU A 339
 None
 1.04A 3a50A-5d0nA:
undetectable		 3a50A-5d0nA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 11 ASN A 315
GLY A 338
ILE A 406
LEU A 302
THR A 402
 None
 1.30A 3bexC-5d0nA:
3.0
3bexD-5d0nA:
2.9		 3bexC-5d0nA:
20.91
3bexD-5d0nA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 10 LEU A 302
THR A 402
ASN A 315
GLY A 338
ILE A 406
 None
 1.29A 3bexC-5d0nA:
3.0
3bexD-5d0nA:
2.9		 3bexC-5d0nA:
20.91
3bexD-5d0nA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 11 ASN A 315
GLY A 338
ILE A 406
LEU A 302
THR A 402
 None
 1.29A 3bf1A-5d0nA:
3.4
3bf1B-5d0nA:
3.2		 3bf1A-5d0nA:
20.91
3bf1B-5d0nA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 11 LEU A 302
THR A 402
ASN A 315
GLY A 338
ILE A 406
 None
 1.28A 3bf1C-5d0nA:
3.2
3bf1D-5d0nA:
3.4		 3bf1C-5d0nA:
20.91
3bf1D-5d0nA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 11 ASN A 315
GLY A 338
ILE A 406
LEU A 302
THR A 402
 None
 1.28A 3bf1E-5d0nA:
3.4
3bf1F-5d0nA:
3.2		 3bf1E-5d0nA:
20.91
3bf1F-5d0nA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 12 LEU A 410
GLY A 408
LEU A 407
ILE A 289
LEU A 291
 None
 0.86A 3gwvA-5d0nA:
undetectable		 3gwvA-5d0nA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		4 / 4 GLY A 146
GLY A 148
THR A 150
LEU A 229
 AMP  A 501 (-3.6A)
MG  A 502 ( 3.3A)
AMP  A 501 ( 3.6A)
None
 0.65A 3si7C-5d0nA:
undetectable
3si7D-5d0nA:
undetectable		 3si7C-5d0nA:
21.45
3si7D-5d0nA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		4 / 5 LEU A 229
GLY A 146
GLY A 148
THR A 150
 None
AMP  A 501 (-3.6A)
MG  A 502 ( 3.3A)
AMP  A 501 ( 3.6A)
 0.61A 3si7C-5d0nA:
undetectable
3si7D-5d0nA:
undetectable		 3si7C-5d0nA:
21.45
3si7D-5d0nA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		4 / 7 PRO A 248
GLY A 246
ALA A 206
ALA A 211
 AMP  A 501 (-4.3A)
None
AMP  A 501 ( 4.5A)
None
 0.76A 3ur0B-5d0nA:
undetectable		 3ur0B-5d0nA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 12 ILE A 140
LEU A 159
GLY A 137
LEU A 166
GLY A 198
 None
 1.09A 3vaqB-5d0nA:
undetectable		 3vaqB-5d0nA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		5 / 12 ILE A 140
LEU A 159
GLY A 137
LEU A 166
GLY A 198
 None
 1.07A 3vasB-5d0nA:
undetectable		 3vasB-5d0nA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		4 / 8 PRO A 390
PHE A 383
PHE A 337
TRP A 389
 None
 1.42A 5amkA-5d0nA:
undetectable		 5amkA-5d0nA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		4 / 7 ALA A 287
TYR A 311
VAL A 290
PRO A 390
 None
 0.83A 6cduA-5d0nA:
undetectable
6cduE-5d0nA:
undetectable		 6cduA-5d0nA:
21.59
6cduE-5d0nA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5d0n PYRUVATE, PHOSPHATE
DIKINASE REGULATORY
PROTEIN,
CHLOROPLASTIC
(Zea
mays) 		4 / 7 VAL A 290
PRO A 390
ALA A 287
TYR A 311
 None
 0.83A 6cduH-5d0nA:
undetectable
6cduI-5d0nA:
undetectable		 6cduH-5d0nA:
21.59
6cduI-5d0nA:
21.59