SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)
5d17 TRANSPOSON TN7
TRANSPOSITION
PROTEIN TNSE

(Escherichia
coli)
5 / 12 LEU A 399
LEU A 514
PRO A 511
VAL A 519
VAL A 508
None
1.10A 1hrkA-5d17A:
undetectable
1hrkA-5d17A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)
5d17 TRANSPOSON TN7
TRANSPOSITION
PROTEIN TNSE

(Escherichia
coli)
5 / 12 PHE A 446
LEU A 465
PHE A 409
LEU A 449
LEU A 399
None
1.07A 1og5A-5d17A:
undetectable
1og5A-5d17A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)
5d17 TRANSPOSON TN7
TRANSPOSITION
PROTEIN TNSE

(Escherichia
coli)
5 / 12 LEU A 399
LEU A 514
PRO A 511
VAL A 519
VAL A 508
None
1.11A 2hrcA-5d17A:
undetectable
2hrcA-5d17A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)
5d17 TRANSPOSON TN7
TRANSPOSITION
PROTEIN TNSE

(Escherichia
coli)
5 / 12 LEU A 399
LEU A 514
PRO A 511
VAL A 519
VAL A 508
None
1.11A 2hrcB-5d17A:
undetectable
2hrcB-5d17A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)
5d17 TRANSPOSON TN7
TRANSPOSITION
PROTEIN TNSE

(Escherichia
coli)
5 / 12 LEU A 399
LEU A 514
PRO A 511
VAL A 519
VAL A 508
None
1.09A 2po7A-5d17A:
undetectable
2po7A-5d17A:
18.28