SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Brucella
abortus) 		4 / 7 PHE A  19
GLY A  14
ILE A  81
GLY A  11
 None
 0.76A 11gsB-5d1iA:
undetectable		 11gsB-5d1iA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Brucella
abortus) 		5 / 11 VAL A  76
LEU A  82
THR A  61
HIS A  64
GLU A  45
 None
 1.38A 1mmtA-5d1iA:
undetectable		 1mmtA-5d1iA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Brucella
abortus) 		5 / 9 LEU A  24
LEU A  26
LEU A  27
ILE A 116
PHE A  19
 None
 1.10A 2f78A-5d1iA:
undetectable		 2f78A-5d1iA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Brucella
abortus) 		5 / 9 LEU A  24
LEU A  26
LEU A  27
ILE A 116
PHE A  19
 None
 1.18A 2f78B-5d1iA:
undetectable		 2f78B-5d1iA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Brucella
abortus) 		5 / 9 LEU A  24
LEU A  26
LEU A  27
ILE A 116
PHE A  19
 None
 1.25A 2f7aA-5d1iA:
undetectable		 2f7aA-5d1iA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Brucella
abortus) 		5 / 11 ARG A  40
GLY A  96
VAL A  76
GLY A  83
ILE A  60
 None
 0.99A 4njvC-5d1iA:
undetectable		 4njvC-5d1iA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Brucella
abortus) 		3 / 3 ARG A 110
ARG A 107
ARG A 115
 None
 1.00A 5vcgA-5d1iA:
undetectable		 5vcgA-5d1iA:
14.56