SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		5 / 9 LEU A  93
LEU A  96
ILE A  19
PHE A 113
ARG A  26
 None
 1.29A 2f78B-5d1vA:
undetectable		 2f78B-5d1vA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		4 / 7 ILE A  22
GLN A  48
LEU A  52
LEU A  96
 None
 0.89A 2qqcB-5d1vA:
undetectable
2qqcC-5d1vA:
undetectable		 2qqcB-5d1vA:
19.55
2qqcC-5d1vA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		4 / 7 LEU A  52
LEU A  96
ILE A  22
GLN A  48
 None
 0.89A 2qqcA-5d1vA:
undetectable
2qqcF-5d1vA:
undetectable		 2qqcA-5d1vA:
18.10
2qqcF-5d1vA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		4 / 7 LEU A  52
LEU A  96
ILE A  22
GLN A  48
 None
 0.95A 2qqcG-5d1vA:
undetectable
2qqcJ-5d1vA:
undetectable		 2qqcG-5d1vA:
18.10
2qqcJ-5d1vA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		4 / 7 LEU A  52
LEU A  96
ILE A  22
GLN A  48
 None
 0.89A 2qqcI-5d1vA:
undetectable
2qqcL-5d1vA:
undetectable		 2qqcI-5d1vA:
18.10
2qqcL-5d1vA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		4 / 5 ARG A  65
THR A  61
GLU A  13
GLU A  46
 None
 1.41A 3ny4A-5d1vA:
undetectable		 3ny4A-5d1vA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		5 / 9 ILE A  19
PHE A  23
TYR A  24
LEU A  52
ALA A  95
 None
 0.75A 3ozvB-5d1vA:
8.2		 3ozvB-5d1vA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		5 / 12 ILE A  19
PHE A  23
TYR A  24
PHE A  37
LEU A  52
 None
None
None
HEM  A 201 (-3.5A)
None
 0.85A 4g1bD-5d1vA:
6.5		 4g1bD-5d1vA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		5 / 12 PHE A 113
ILE A  22
ALA A  99
THR A  15
LEU A  52
 None
 1.24A 5jkvA-5d1vA:
undetectable		 5jkvA-5d1vA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 5d1v GLOBIN
(Chloroflexus
aurantiacus) 		5 / 11 MET A  92
LEU A  52
ARG A  18
ILE A  10
MET A 109
 None
 1.22A 6fgcA-5d1vA:
undetectable		 6fgcA-5d1vA:
21.21