SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d1x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 5d1x D4-30 HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA B  40
ARG B  38
GLN B  43
GLU B  46
 None
 0.90A 1lqtB-5d1xB:
undetectable		 1lqtB-5d1xB:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 5d1x D4-30 HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA B  40
ARG B  38
GLN B  43
GLU B  46
 None
 0.92A 1lquB-5d1xB:
undetectable		 1lquB-5d1xB:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5d1x D4-30 HEAVY CHAIN
(Homo
sapiens) 		4 / 8 LEU B  67
THR B 107
TYR B  90
ILE B  48
 None
 1.08A 1qvtA-5d1xB:
undetectable		 1qvtA-5d1xB:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5d1x D4-30 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 11 GLY B  50
SER B  35
LEU B 100
HIS E 434
ALA B  56
 None
 1.24A 2a58A-5d1xB:
undetectable
2a58E-5d1xB:
undetectable		 2a58A-5d1xB:
19.33
2a58E-5d1xB:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5d1x D4-30 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 12 HIS E 434
ALA B  56
GLY B  50
SER B  35
LEU B 100
 None
 1.25A 2a58A-5d1xE:
undetectable
2a58B-5d1xE:
undetectable		 2a58A-5d1xE:
21.15
2a58B-5d1xE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5d1x D4-30 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 12 HIS E 434
ALA B  56
GLY B  50
SER B  35
LEU B 100
 None
 1.25A 2a58B-5d1xE:
undetectable
2a58C-5d1xE:
undetectable		 2a58B-5d1xE:
21.15
2a58C-5d1xE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5d1x D4-30 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 11 HIS E 434
ALA B  56
GLY B  50
SER B  35
LEU B 100
 None
 1.25A 2a58C-5d1xE:
undetectable
2a58D-5d1xE:
undetectable		 2a58C-5d1xE:
21.15
2a58D-5d1xE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5d1x D4-30 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 12 HIS E 434
ALA B  56
GLY B  50
SER B  35
LEU B 100
 None
 1.25A 2a58D-5d1xE:
undetectable
2a58E-5d1xE:
undetectable		 2a58D-5d1xE:
21.15
2a58E-5d1xE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5d1x D4-30 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		4 / 6 PHE B  54
PHE E 366
TYR E 391
HIS B  32
 None
 1.22A 3lb3B-5d1xB:
undetectable		 3lb3B-5d1xB:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5d1x D4-30 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 TYR B 102
HIS B  32
ARG B  94
 None
 0.95A 4htfA-5d1xB:
undetectable		 4htfA-5d1xB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5d1x IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
P5 HEAVY CHAIN
(Homo
sapiens;
Staphylococcus
aureus) 		4 / 7 LEU E 345
TYR C 100
THR C  97
ASP C 101
 None
 1.13A 5jq7B-5d1xE:
undetectable		 5jq7B-5d1xE:
20.96