SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 5d1z D4-10 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		3 / 3 PHE I 194
LEU D  73
SER D  31
 None
 0.86A 1e7aA-5d1zI:
undetectable		 1e7aA-5d1zI:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 5d1z IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		4 / 5 ALA I 257
GLN I 258
ILE I 151
ARG I 149
 None
 1.10A 2z0aA-5d1zI:
undetectable		 2z0aA-5d1zI:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 5d1z IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		5 / 12 LEU I 189
LEU I 187
PHE I 153
HIS I 166
SER I 238
 None
 1.37A 4aqlA-5d1zI:
undetectable		 4aqlA-5d1zI:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5d1z Y10 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 TYR B  95
LEU B  82
LEU B  87
ARG B  68
 None
 1.28A 4em2A-5d1zB:
undetectable		 4em2A-5d1zB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5d1z D4-10 HEAVY CHAIN
(Homo
sapiens) 		5 / 10 PHE D 137
GLY D 133
THR D 220
VAL D 213
VAL D 222
 None
 1.21A 4jx1B-5d1zD:
undetectable		 4jx1B-5d1zD:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5d1z IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
Y10 HEAVY CHAIN
(Homo
sapiens;
Staphylococcus
aureus) 		3 / 3 TYR B 108
GLN I 127
TRP B  34
 None
 0.93A 4kn2C-5d1zB:
undetectable		 4kn2C-5d1zB:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5d1z D4-10 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 VAL D 184
ILE D  50
PRO D  43
THR D  88
 None
 1.30A 4ze1A-5d1zD:
undetectable		 4ze1A-5d1zD:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5d1z D4-10 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		3 / 3 LEU D  73
ILE D  53
TYR I 165
 None
 0.70A 5uunB-5d1zD:
undetectable		 5uunB-5d1zD:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 5d1z IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		6 / 12 VAL I 200
PHE I 198
ILE I 209
ILE I 223
LEU I 189
THR I 252
 None
 1.38A 5uvmB-5d1zI:
undetectable		 5uvmB-5d1zI:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5d1z D4-10 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 GLU D 163
PHE D 161
HIS D 215
THR D 125
 None
 1.23A 6b58A-5d1zD:
undetectable		 6b58A-5d1zD:
17.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 5d1z Y10 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 TYR B  61
GLY B  67
THR B  70
 None
 0.18A 6cjkB-5d1zB:
22.9		 6cjkB-5d1zB:
60.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5d1z D4-10 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL D 222
THR D 220
VAL D 226
GLY D 133
VAL D 167
 None
 0.97A 6drzA-5d1zD:
undetectable		 6drzA-5d1zD:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 5d1z IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
Y10 HEAVY CHAIN
(Homo
sapiens;
Staphylococcus
aureus) 		3 / 3 ASP B  63
ASP B  51
ASN I 135
 None
 0.79A 6gngB-5d1zB:
undetectable		 6gngB-5d1zB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5d1z D4-10 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 THR D  88
VAL D 126
VAL D 124
VAL D  69
TYR D  95
 None
 1.36A 6iblA-5d1zD:
undetectable		 6iblA-5d1zD:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5d1z D4-10 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Homo
sapiens;
Staphylococcus
aureus) 		5 / 12 PHE D  55
GLY D  57
SER I 169
HIS I 166
TYR I 249
 None
 1.38A 6md4A-5d1zD:
undetectable		 6md4A-5d1zD:
12.64