SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 5d3i STAPHYLOCOCCAL
SUPERANTIGEN-LIKE
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 GLU B 205
TYR B 145
VAL B 203
PHE B 265
ASP B 264
 None
 1.43A 2qeoA-5d3iB:
undetectable		 2qeoA-5d3iB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 5d3i STAPHYLOCOCCAL
SUPERANTIGEN-LIKE
PROTEIN 3
(Staphylococcus
aureus) 		4 / 8 TYR B 214
GLU B 205
TYR B 209
PHE B 168
 None
 0.85A 3jz0B-5d3iB:
undetectable		 3jz0B-5d3iB:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5d3i STAPHYLOCOCCAL
SUPERANTIGEN-LIKE
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 TYR B 278
GLU B 273
LEU B 267
VAL B 323
ILE B 286
 None
 1.28A 4k39A-5d3iB:
undetectable		 4k39A-5d3iB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5d3i STAPHYLOCOCCAL
SUPERANTIGEN-LIKE
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 ILE B 318
LEU B 260
ILE B 286
ARG B 268
ILE B 321
 None
 1.09A 4x5jA-5d3iB:
undetectable		 4x5jA-5d3iB:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5d3i STAPHYLOCOCCAL
SUPERANTIGEN-LIKE
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 GLY B 284
TYR B 138
HIS B 275
ARG B 268
LEU B 271
 None
 1.38A 6bp4B-5d3iB:
undetectable		 6bp4B-5d3iB:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 5d3i STAPHYLOCOCCAL
SUPERANTIGEN-LIKE
PROTEIN 3
(Staphylococcus
aureus) 		3 / 3 LEU B 271
LEU B 300
ARG B 268
 None
 0.65A 6fgcA-5d3iB:
undetectable		 6fgcA-5d3iB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 5d3i STAPHYLOCOCCAL
SUPERANTIGEN-LIKE
PROTEIN 3
(Staphylococcus
aureus) 		3 / 3 LEU B 271
LEU B 300
ARG B 268
 None
 0.66A 6fgdA-5d3iB:
undetectable		 6fgdA-5d3iB:
19.43