SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 THR A 205
VAL A 174
LEU A 134
LEU A 172
LEU A  71
 GDP  A 801 ( 4.8A)
None
None
None
None
 1.18A 1mx1C-5d3qA:
1.9		 1mx1C-5d3qA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 4 GLY A 202
SER A 175
VAL A 219
LEU A 227
 None
 0.92A 1yajB-5d3qA:
undetectable		 1yajB-5d3qA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 LEU A 181
ILE A 204
GLY A 202
ASP A 194
GLY A 197
 None
 1.01A 1zz1C-5d3qA:
undetectable		 1zz1C-5d3qA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 8 HIS A 288
VAL A  13
LEU A 296
THR A 292
 None
 0.91A 2gehA-5d3qA:
undetectable		 2gehA-5d3qA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 GLY A 233
GLY A 273
ALA A 177
LEU A 268
LEU A 207
 None
 1.15A 3mteA-5d3qA:
undetectable		 3mteA-5d3qA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 GLY A 233
GLY A 273
ALA A 177
LEU A 268
LEU A 207
 None
 1.09A 3p2kB-5d3qA:
undetectable		 3p2kB-5d3qA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 4 ALA A 251
VAL A 235
GLY A 273
THR A 274
 None
GDP  A 801 (-4.0A)
None
None
 1.12A 4ubeA-5d3qA:
undetectable		 4ubeA-5d3qA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 7 LEU A  31
LEU A 296
ARG A 297
LEU A 300
 None
 0.72A 4wg0B-5d3qA:
undetectable
4wg0C-5d3qA:
undetectable		 4wg0B-5d3qA:
4.20
4wg0C-5d3qA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 7 LEU A 296
ARG A 297
LEU A 300
LEU A  31
 None
 0.73A 4wg0L-5d3qA:
undetectable
4wg0M-5d3qA:
undetectable		 4wg0L-5d3qA:
4.20
4wg0M-5d3qA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 LEU A 305
PRO A  32
LEU A  31
ASN A 298
LEU A 735
 None
 1.11A 4x61A-5d3qA:
undetectable		 4x61A-5d3qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 7 VAL A 124
ALA A  81
LEU A  71
LEU A  69
 None
 0.50A 5jq7A-5d3qA:
undetectable		 5jq7A-5d3qA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 5 SER A 175
VAL A 174
GLY A  38
ALA A 186
 None
 1.03A 5k50A-5d3qA:
undetectable		 5k50A-5d3qA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LUH_A_SRYA304_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 10 ASP A 194
ASP A  30
HIS A 288
ILE A 289
THR A 292
 None
 0.96A 5luhA-5d3qA:
0.0		 5luhA-5d3qA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LUH_B_SRYB303_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 10 ASP A 194
ASP A  30
HIS A 288
ILE A 289
THR A 292
 None
 0.97A 5luhB-5d3qA:
0.0		 5luhB-5d3qA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 8 THR A 200
GLN A 284
VAL A 234
GLY A 233
 None
 0.98A 5nzyA-5d3qA:
undetectable		 5nzyA-5d3qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 GLU A 727
LEU A  31
ASP A  28
ALA A 734
GLN A  72
 None
 1.28A 5syeB-5d3qA:
undetectable		 5syeB-5d3qA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 VAL A  36
ALA A 253
LEU A 277
PHE A  51
LEU A  48
 None
 1.26A 6a7pB-5d3qA:
undetectable		 6a7pB-5d3qA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 VAL A  36
ALA A 254
LEU A 277
PHE A  51
LEU A  48
 None
 1.18A 6a7pB-5d3qA:
undetectable		 6a7pB-5d3qA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		5 / 12 VAL A  70
LEU A 296
LEU A  16
THR A 292
LEU A 285
 None
 1.14A 6b0lB-5d3qA:
undetectable		 6b0lB-5d3qA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 5d3q DYNAMIN-1,DYNAMIN-1
(Homo
sapiens) 		4 / 4 PRO A  58
LEU A  69
VAL A  97
ARG A  98
 None
 1.35A 6fgdA-5d3qA:
1.8		 6fgdA-5d3qA:
22.71