SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d50'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRZ_A_ACTA1467_0 (DEOXYRIBODIPYRIMIDIN E PHOTOLYASE)	5d50	REPRESSOR (Salmonella virus SPN1S)	4 / 5	ARG A 54 ASP A 68 ILE A 7 GLU A 57	None	1.39A	2xrzA-5d50A: undetectable 2xrzB-5d50A: undetectable	2xrzA-5d50A: 19.28 2xrzB-5d50A: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MX0_A_BCZA513_1 (NEURAMINIDASE)	5d50	REPRESSOR ANTI-REPRESSOR PROTEIN (Salmonella virus SPN1S; Salmonella virus SPN1S)	3 / 3	ARG A 54 ASP E 47 ARG A 8	None	0.97A	4mx0A-5d50A: undetectable	4mx0A-5d50A: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WAN_C_ACTC303_0 (BRANCHPOINT-BRIDGING PROTEIN)	5d50	REPRESSOR ANTI-REPRESSOR PROTEIN (Salmonella virus SPN1S; Salmonella virus SPN1S)	3 / 3	ASP E 47 ARG A 8 PRO A 50	None	0.87A	4wanC-5d50E: undetectable	4wanC-5d50E: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F88_A_STRA502_1 (CYTOCHROME P450 CYP260A1)	5d50	REPRESSOR (Salmonella virus SPN1S)	4 / 6	PHE A 149 ALA A 148 SER A 143 THR A 137	None	0.88A	6f88A-5d50A: undetectable	6f88A-5d50A: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XRZ_A_ACTA1467_0","DEOXYRIBODIPYRIMIDINE PHOTOLYASE","5d50","REPRESSOR","Salmonella virus SPN1S",4,"ARG A  54;ASP A  68;ILE A   7;GLU A  57","None","1.39A","2xrzA-5d50A:undetectable;2xrzB-5d50A:undetectable","2xrzA-5d50A:19.28;2xrzB-5d50A:19.28"],["4MX0_A_BCZA513_1","NEURAMINIDASE","5d50","REPRESSOR;ANTI-REPRESSOR PROTEIN","Salmonella virus SPN1S;Salmonella virus SPN1S",3,"ARG A  54;ASP E  47;ARG A   8","None","0.97A","4mx0A-5d50A:undetectable","4mx0A-5d50A:19.17"],["4WAN_C_ACTC303_0","BRANCHPOINT-BRIDGING PROTEIN","5d50","REPRESSOR;ANTI-REPRESSOR PROTEIN","Salmonella virus SPN1S;Salmonella virus SPN1S",3,"ASP E  47;ARG A   8;PRO A  50","None","0.87A","4wanC-5d50E:undetectable","4wanC-5d50E:24.81"],["6F88_A_STRA502_1","CYTOCHROME P450 CYP260A1","5d50","REPRESSOR","Salmonella virus SPN1S",4,"PHE A 149;ALA A 148;SER A 143;THR A 137","None","0.88A","6f88A-5d50A:undetectable","6f88A-5d50A:20.00"]]