SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		3 / 3 TRP A  38
ALA A  41
VAL A 113
 FLC  A 201 (-3.3A)
None
None
 0.99A 1bdwA-5d55A:
undetectable
1bdwB-5d55A:
undetectable		 1bdwA-5d55A:
6.37
1bdwB-5d55A:
6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 9 GLY A  69
VAL A  37
ILE A  26
GLY A  24
ILE A  67
 None
 1.03A 1hpvA-5d55A:
undetectable		 1hpvA-5d55A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 9 ILE A  26
PHE A  94
GLY A  24
ILE A   3
ALA A   1
 None
 1.30A 1mrgA-5d55A:
undetectable		 1mrgA-5d55A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 11 GLY A  69
VAL A  37
ILE A  26
GLY A  24
ILE A  67
 None
 0.82A 1n49B-5d55A:
undetectable		 1n49B-5d55A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 11 GLY A  69
VAL A  37
ILE A  26
GLY A  24
ILE A  67
 None
 0.84A 1n49C-5d55A:
undetectable		 1n49C-5d55A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 12 LEU A 130
ILE A   3
LEU A   5
ILE A  96
VAL A  83
 None
 1.09A 2ygnA-5d55A:
undetectable		 2ygnA-5d55A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 9 ILE A  26
PHE A  94
GLY A  24
ILE A   3
ALA A   1
 None
 1.31A 4yp2B-5d55A:
undetectable		 4yp2B-5d55A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 9 ILE A  26
PHE A  94
GLY A  24
ILE A   3
ALA A   1
 None
 1.30A 5cf9B-5d55A:
undetectable		 5cf9B-5d55A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5d55 HDAB,HDAA (ADHESIN),
HUS-ASSOCIATED
DIFFUSE ADHERENCE
(Escherichia
coli) 		5 / 12 ILE A  93
ILE A  67
GLY A  68
LYS A  20
VAL A  37
 None
 1.08A 5twjC-5d55A:
undetectable		 5twjC-5d55A:
22.73