SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		5 / 11 PHE A 100
GLU A  49
VAL A  51
ILE A  52
PHE A  53
 None
 1.23A 2dg4A-5d5tA:
undetectable		 2dg4A-5d5tA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		5 / 12 SER A 263
VAL A 265
THR A 159
PHE A 136
ILE A 137
 None
 1.38A 2vdyA-5d5tA:
undetectable		 2vdyA-5d5tA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 5 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.38A 3n62A-5d5tA:
0.0
3n62B-5d5tA:
0.0		 3n62A-5d5tA:
21.35
3n62B-5d5tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 5 MET A 186
VAL A  55
TRP A  58
PHE A 221
 None
 1.39A 3n62A-5d5tA:
0.0
3n62B-5d5tA:
0.0		 3n62A-5d5tA:
21.35
3n62B-5d5tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 5 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.37A 3n65A-5d5tA:
0.0
3n65B-5d5tA:
0.0		 3n65A-5d5tA:
21.35
3n65B-5d5tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		3 / 3 TYR A 150
ASP A 140
ASP A 116
 None
 0.93A 3ou6B-5d5tA:
4.1		 3ou6B-5d5tA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 5 GLU A  43
GLY A  44
TYR A  69
GLU A  46
 None
 1.29A 3w9tA-5d5tA:
undetectable		 3w9tA-5d5tA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 5 GLU A  43
GLY A  44
TYR A  69
GLU A  46
 None
 1.27A 3w9tC-5d5tA:
undetectable		 3w9tC-5d5tA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 5 GLU A  43
GLY A  44
TYR A  69
GLU A  46
 None
 1.28A 3w9tD-5d5tA:
undetectable		 3w9tD-5d5tA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 5 GLU A  43
GLY A  44
TYR A  69
GLU A  46
 None
 1.28A 3w9tG-5d5tA:
undetectable		 3w9tG-5d5tA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 MET A 186
VAL A  55
TRP A  58
PHE A 221
 None
 1.43A 4c39A-5d5tA:
undetectable
4c39B-5d5tA:
undetectable		 4c39A-5d5tA:
21.35
4c39B-5d5tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		5 / 12 SER A 263
VAL A 265
THR A 159
PHE A 136
ILE A 137
 None
 1.44A 4c49B-5d5tA:
undetectable		 4c49B-5d5tA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		5 / 12 SER A 263
VAL A 265
THR A 159
PHE A 136
ILE A 137
 None
 1.40A 4c49C-5d5tA:
undetectable		 4c49C-5d5tA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.48A 4ctqA-5d5tA:
0.0
4ctqB-5d5tA:
undetectable		 4ctqA-5d5tA:
21.35
4ctqB-5d5tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.38A 4uh6A-5d5tA:
undetectable
4uh6B-5d5tA:
undetectable		 4uh6A-5d5tA:
22.09
4uh6B-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 4 GLY A  59
LEU A  42
PHE A  41
ILE A 137
 None
 0.97A 4xv2A-5d5tA:
undetectable		 4xv2A-5d5tA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.31A 5ad4A-5d5tA:
undetectable
5ad4B-5d5tA:
undetectable		 5ad4A-5d5tA:
21.35
5ad4B-5d5tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 6 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.36A 5adfA-5d5tA:
0.0
5adfB-5d5tA:
0.1		 5adfA-5d5tA:
22.09
5adfB-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.41A 5adgA-5d5tA:
undetectable
5adgB-5d5tA:
undetectable		 5adgA-5d5tA:
22.09
5adgB-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 6 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.34A 5adiA-5d5tA:
undetectable
5adiB-5d5tA:
0.4		 5adiA-5d5tA:
22.09
5adiB-5d5tA:
22.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		6 / 12 GLY A  54
ILE A  78
LEU A  97
THR A 118
GLY A 122
GLY A 184
 None
 0.58A 5d4uA-5d5tA:
36.0		 5d4uA-5d5tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_A_SAMA301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 4 LYS A  34
ASP A  77
GLU A 139
THR A 185
 None
 0.29A 5d4uA-5d5tA:
36.0		 5d4uA-5d5tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		6 / 12 GLY A  54
ILE A  78
LEU A  97
THR A 118
GLY A 122
GLY A 184
 None
 0.60A 5d4uB-5d5tA:
35.7		 5d4uB-5d5tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_B_SAMB301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 4 LYS A  34
ASP A  77
GLU A 139
THR A 185
 None
 0.33A 5d4uB-5d5tA:
35.7		 5d4uB-5d5tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		7 / 12 GLY A  54
ILE A  78
LEU A  97
THR A 118
GLY A 122
ILE A 123
GLY A 184
 None
 0.64A 5d4uC-5d5tA:
35.9		 5d4uC-5d5tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_C_SAMC301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 4 LYS A  34
ASP A  77
GLU A 139
THR A 185
 None
 0.37A 5d4uC-5d5tA:
35.9		 5d4uC-5d5tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		7 / 12 GLY A  54
ILE A  78
LEU A  97
THR A 118
GLY A 122
ILE A 123
GLY A 184
 None
 0.55A 5d4uD-5d5tA:
36.2		 5d4uD-5d5tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 4 LYS A  34
ASP A  77
GLU A 139
THR A 185
 None
 0.28A 5d4uD-5d5tA:
36.2		 5d4uD-5d5tA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.47A 5fvuA-5d5tA:
undetectable
5fvuB-5d5tA:
undetectable		 5fvuA-5d5tA:
22.09
5fvuB-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 6 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.44A 5fvxA-5d5tA:
0.0
5fvxB-5d5tA:
0.6		 5fvxA-5d5tA:
22.09
5fvxB-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.46A 5uo1A-5d5tA:
undetectable
5uo1B-5d5tA:
undetectable		 5uo1A-5d5tA:
22.09
5uo1B-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 MET A 186
VAL A  55
TRP A  58
PHE A 221
 None
 1.47A 5uo2A-5d5tA:
undetectable
5uo2B-5d5tA:
undetectable		 5uo2A-5d5tA:
22.09
5uo2B-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.44A 5uo2A-5d5tA:
undetectable
5uo2B-5d5tA:
undetectable		 5uo2A-5d5tA:
22.09
5uo2B-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.41A 5uo4A-5d5tA:
undetectable
5uo4B-5d5tA:
undetectable		 5uo4A-5d5tA:
22.09
5uo4B-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		5 / 12 ALA A  63
GLU A  49
LEU A 113
ILE A 114
VAL A  76
 None
 1.31A 5vlmB-5d5tA:
undetectable		 5vlmB-5d5tA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.42A 5vuvA-5d5tA:
undetectable
5vuvB-5d5tA:
undetectable		 5vuvA-5d5tA:
22.09
5vuvB-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 6 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.47A 5vuxA-5d5tA:
0.2
5vuxB-5d5tA:
undetectable		 5vuxA-5d5tA:
22.09
5vuxB-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.39A 5vv4A-5d5tA:
undetectable
5vv4B-5d5tA:
undetectable		 5vv4A-5d5tA:
22.09
5vv4B-5d5tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.35A 6auqA-5d5tA:
undetectable
6auqB-5d5tA:
undetectable		 6auqA-5d5tA:
10.86
6auqB-5d5tA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.42A 6auzA-5d5tA:
undetectable
6auzB-5d5tA:
undetectable		 6auzA-5d5tA:
17.96
6auzB-5d5tA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.43A 6av0A-5d5tA:
undetectable
6av0B-5d5tA:
undetectable		 6av0A-5d5tA:
17.96
6av0B-5d5tA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.37A 6av2A-5d5tA:
undetectable
6av2B-5d5tA:
undetectable		 6av2A-5d5tA:
17.96
6av2B-5d5tA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.49A 6av3A-5d5tA:
undetectable
6av3B-5d5tA:
undetectable		 6av3A-5d5tA:
17.96
6av3B-5d5tA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d5t UNCHARACTERIZED
PROTEIN MJ0489
(Methanocaldococc
us
jannaschii) 		4 / 7 PHE A 221
MET A 186
VAL A  55
TRP A  58
 None
 1.45A 6av5A-5d5tA:
undetectable
6av5B-5d5tA:
undetectable		 6av5A-5d5tA:
17.96
6av5B-5d5tA:
17.96