SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_B_SVRB501_2 (PHOSPHOLIPASE A2)	5d5x	PUTATIVE TRANSCRIPTION FACTOR (Chaetomium thermophilum)	5 / 11	VAL B 70 LEU B 72 ILE B 81 PRO B 54 SER B 55	None	1.30A	3bjwB-5d5xB: undetectable	3bjwB-5d5xB: 18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NUV_A_ASDA126_1 (STEROID DELTA-ISOMERASE)	5d5x	PUTATIVE TRANSCRIPTION FACTOR (Chaetomium thermophilum)	5 / 12	PHE B 43 LEU B 82 PHE B 91 VAL B 71 PHE B 69	None	1.16A	3nuvA-5d5xB: undetectable	3nuvA-5d5xB: 20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A94_A_ZOTA3001_0 (5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562)	5d5x	PUTATIVE TRANSCRIPTION FACTOR (Chaetomium thermophilum)	5 / 12	PHE B 86 PHE B 91 PHE B 77 ASN B 74 VAL B 95	None	1.24A	6a94A-5d5xB: undetectable	6a94A-5d5xB: 13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AWT_D_BEZD202_0 (PR 10 PROTEIN)	5d5x	PUTATIVE TRANSCRIPTION FACTOR (Chaetomium thermophilum)	3 / 3	PHE B 43 ASP B 42 LYS B 46	None	0.86A	6awtD-5d5xB: undetectable	6awtD-5d5xB: 24.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJW_B_SVRB501_2","PHOSPHOLIPASE A2","5d5x","PUTATIVE TRANSCRIPTION FACTOR","Chaetomium thermophilum",5,"VAL B  70;LEU B  72;ILE B  81;PRO B  54;SER B  55","None","1.30A","3bjwB-5d5xB:undetectable","3bjwB-5d5xB:18.40"],["3NUV_A_ASDA126_1","STEROID DELTA-ISOMERASE","5d5x","PUTATIVE TRANSCRIPTION FACTOR","Chaetomium thermophilum",5,"PHE B  43;LEU B  82;PHE B  91;VAL B  71;PHE B  69","None","1.16A","3nuvA-5d5xB:undetectable","3nuvA-5d5xB:20.29"],["6A94_A_ZOTA3001_0","5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562","5d5x","PUTATIVE TRANSCRIPTION FACTOR","Chaetomium thermophilum",5,"PHE B  86;PHE B  91;PHE B  77;ASN B  74;VAL B  95","None","1.24A","6a94A-5d5xB:undetectable","6a94A-5d5xB:13.56"],["6AWT_D_BEZD202_0","PR 10 PROTEIN","5d5x","PUTATIVE TRANSCRIPTION FACTOR","Chaetomium thermophilum",3,"PHE B  43;ASP B  42;LYS B  46","None","0.86A","6awtD-5d5xB:undetectable","6awtD-5d5xB:24.66"]]