SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d66'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		4 / 6 THR A 142
LEU A 112
GLY A 115
TYR A 111
 None
 1.23A 1gtiC-5d66A:
undetectable		 1gtiC-5d66A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 LEU A 172
GLY A 141
ARG A 138
ASP A 108
ALA A 116
 None
CL  A 301 (-3.5A)
None
None
None
 0.99A 2bm9E-5d66A:
undetectable		 2bm9E-5d66A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		5 / 9 ASN A 189
ILE A 193
ILE A 226
GLY A 184
ALA A 180
 None
 1.30A 2dtjA-5d66A:
undetectable
2dtjB-5d66A:
undetectable		 2dtjA-5d66A:
21.00
2dtjB-5d66A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		4 / 8 ASN A  85
THR A  82
LEU A  78
ALA A  89
 CL  A 302 ( 4.1A)
None
None
None
 0.79A 3kp6A-5d66A:
undetectable		 3kp6A-5d66A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		5 / 9 ASN A  85
THR A  82
ALA A  81
LEU A  78
ALA A  89
 CL  A 302 ( 4.1A)
None
None
None
None
 1.13A 3kp6B-5d66A:
undetectable		 3kp6B-5d66A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 ALA A 116
LEU A 127
LEU A 133
ALA A 143
LEU A 144
 None
 1.19A 3r9cA-5d66A:
undetectable		 3r9cA-5d66A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		4 / 8 ALA A  90
ILE A  94
LEU A  78
ALA A 114
 None
 0.71A 3r9tA-5d66A:
undetectable		 3r9tA-5d66A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		5 / 9 LEU A 127
LEU A 123
ILE A 160
PRO A 146
ALA A 147
 None
None
None
CL  A 301 ( 4.5A)
None
 1.13A 5og9A-5d66A:
undetectable		 5og9A-5d66A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5d66 UNCHARACTERIZED
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 LEU A 127
LEU A 123
ILE A 160
PRO A 146
ALA A 147
 None
None
None
CL  A 301 ( 4.5A)
None
 1.14A 5og9B-5d66A:
undetectable		 5og9B-5d66A:
19.78