SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5d67 EF-HAND
CALCIUM-BINDING
DOMAIN-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 8 TRP A1069
CYH A1053
LEU A1068
MET A1072
 None
 1.36A 1uw6A-5d67A:
undetectable
1uw6B-5d67A:
undetectable		 1uw6A-5d67A:
20.19
1uw6B-5d67A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5d67 EF-HAND
CALCIUM-BINDING
DOMAIN-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 8 TRP A1069
CYH A1053
LEU A1068
MET A1072
 None
 1.35A 1uw6D-5d67A:
undetectable
1uw6E-5d67A:
undetectable		 1uw6D-5d67A:
20.19
1uw6E-5d67A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5d67 EF-HAND
CALCIUM-BINDING
DOMAIN-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 8 TRP A1069
CYH A1053
LEU A1068
MET A1072
 None
 1.33A 1uw6G-5d67A:
undetectable
1uw6H-5d67A:
undetectable		 1uw6G-5d67A:
20.19
1uw6H-5d67A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5d67 EF-HAND
CALCIUM-BINDING
DOMAIN-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 8 TRP A1069
CYH A1053
LEU A1068
MET A1072
 None
 1.35A 1uw6P-5d67A:
undetectable
1uw6Q-5d67A:
undetectable		 1uw6P-5d67A:
20.19
1uw6Q-5d67A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5d67 EF-HAND
CALCIUM-BINDING
DOMAIN-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 8 LEU A1068
MET A1072
TRP A1069
CYH A1053
 None
 1.29A 1uw6P-5d67A:
undetectable
1uw6T-5d67A:
undetectable		 1uw6P-5d67A:
20.19
1uw6T-5d67A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5d67 EF-HAND
CALCIUM-BINDING
DOMAIN-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 7 ALA A1021
THR A1023
TYR A1026
PRO A1073
 None
 0.91A 6cduA-5d67A:
undetectable
6cduE-5d67A:
undetectable		 6cduA-5d67A:
15.74
6cduE-5d67A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5d67 EF-HAND
CALCIUM-BINDING
DOMAIN-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 7 PRO A1073
ALA A1021
THR A1023
TYR A1026
 None
 0.91A 6cduH-5d67A:
undetectable
6cduI-5d67A:
undetectable		 6cduH-5d67A:
15.74
6cduI-5d67A:
15.74