SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 ILE A 383
ILE A 336
GLN A 319
MET A 346
ALA A 342
 None
 1.38A 1ki7B-5d6aA:
undetectable		 1ki7B-5d6aA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 LEU A 366
GLY A 387
GLY A 389
TYR A 391
ILE A 383
 None
 1.08A 1p91B-5d6aA:
undetectable		 1p91B-5d6aA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 ILE A  92
ALA A  91
LEU A  33
ILE A  35
PHE A  82
 None
 1.31A 1y0xX-5d6aA:
undetectable		 1y0xX-5d6aA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 6 ALA A 331
SER A 332
ILE A 258
ASP A 273
 None
 1.01A 1yc2A-5d6aA:
undetectable		 1yc2A-5d6aA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 11 VAL A 186
PHE A 209
THR A 237
ILE A 239
LEU A 250
 None
 0.98A 1z11A-5d6aA:
undetectable		 1z11A-5d6aA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 11 VAL A 186
PHE A 209
THR A 237
ILE A 239
LEU A 250
 None
 0.97A 1z11B-5d6aA:
undetectable		 1z11B-5d6aA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 9 GLY A 525
SER A 106
SER A  95
ASP A 483
ASP A 526
 None
 1.50A 2j2pB-5d6aA:
undetectable
2j2pC-5d6aA:
undetectable		 2j2pB-5d6aA:
15.26
2j2pC-5d6aA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 6 MET A 536
PRO A 532
ILE A 488
LEU A 495
 None
 1.23A 2wekB-5d6aA:
undetectable		 2wekB-5d6aA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 PHE A 209
LEU A 250
ALA A 406
ALA A 211
VAL A 217
 None
 1.24A 3cwkA-5d6aA:
1.2		 3cwkA-5d6aA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 THR A 218
LEU A 250
SER A 214
ILE A 239
THR A 237
 None
 1.24A 3frqA-5d6aA:
undetectable		 3frqA-5d6aA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		3 / 3 ASP A 103
PHE A 518
SER A 106
 None
 0.94A 3i5uB-5d6aA:
undetectable		 3i5uB-5d6aA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 8 LEU A 122
GLN A  39
ALA A  46
SER A  47
 None
 0.90A 3kp6A-5d6aA:
undetectable		 3kp6A-5d6aA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 4 SER A  95
SER A 104
THR A 105
SER A 106
 None
 1.20A 3loqA-5d6aA:
undetectable		 3loqA-5d6aA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 ILE A 239
ILE A 382
ALA A 253
LEU A 250
ILE A 270
 None
 0.89A 3uvvA-5d6aA:
undetectable		 3uvvA-5d6aA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 9 ILE A 379
LEU A 334
PRO A 532
SER A 510
GLY A 274
 None
 1.39A 3w1wB-5d6aA:
1.7		 3w1wB-5d6aA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 5 GLU A 125
GLY A 126
TYR A  16
ASP A  41
 None
 0.93A 3w9tD-5d6aA:
undetectable		 3w9tD-5d6aA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 PHE A 466
LEU A 513
ILE A 509
ALA A 538
MET A 542
 None
 1.22A 4a83A-5d6aA:
undetectable		 4a83A-5d6aA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 7 ASP A 483
SER A 106
HIS A  97
SER A 104
 None
 1.03A 4k7gB-5d6aA:
undetectable		 4k7gB-5d6aA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 7 ARG A 117
ILE A 146
PHE A 118
LEU A  33
 None
 1.08A 4mmcA-5d6aA:
undetectable		 4mmcA-5d6aA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 11 ILE A 488
ALA A 487
LEU A 464
ALA A 458
LEU A 513
 None
 1.14A 4nqaA-5d6aA:
undetectable		 4nqaA-5d6aA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 7 ILE A 236
LEU A 373
LEU A 366
ILE A 336
 None
 0.85A 4rmjA-5d6aA:
undetectable		 4rmjA-5d6aA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 8 ILE A 146
ALA A  51
PHE A 118
PRO A 123
 None
 0.81A 5m0oC-5d6aA:
undetectable		 5m0oC-5d6aA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 5 LEU A 464
ALA A 538
LEU A 539
LEU A 476
 None
 0.87A 5vkqA-5d6aA:
undetectable
5vkqD-5d6aA:
undetectable		 5vkqA-5d6aA:
16.20
5vkqD-5d6aA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 8 SER A 457
ARG A 455
ASN A 486
ASP A 526
 None
 1.31A 5vunA-5d6aA:
undetectable		 5vunA-5d6aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 8 SER A 457
ARG A 455
ASN A 486
ASP A 526
 None
 1.34A 5vunB-5d6aA:
undetectable		 5vunB-5d6aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 8 SER A 457
ARG A 455
ASN A 486
ASP A 526
 None
 1.35A 5vuoB-5d6aA:
undetectable		 5vuoB-5d6aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		5 / 12 VAL A 535
PRO A 530
HIS A  97
SER A  95
GLY A 525
 None
 1.47A 5xioA-5d6aA:
2.2		 5xioA-5d6aA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		3 / 3 MET A 385
ASP A 390
ARG A 374
 None
 1.05A 5z6jA-5d6aA:
undetectable		 5z6jA-5d6aA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		3 / 3 MET A 385
ASP A 390
ARG A 374
 None
 1.02A 5z6kA-5d6aA:
undetectable		 5z6kA-5d6aA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d6a PREDICTED ATPASE OF
THE ABC CLASS
(Vibrio
vulnificus) 		4 / 6 ILE A 114
ALA A  74
ARG A  75
ASP A 515
 None
 0.94A 6hu9m-5d6aA:
undetectable
6hu9q-5d6aA:
0.6		 6hu9m-5d6aA:
21.38
6hu9q-5d6aA:
13.94