SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)
5d6g 50S RIBOSOMAL
PROTEIN L10

(Methanocaldococc
us
jannaschii)
5 / 12 PRO A 137
MET A 135
LEU A 141
ILE A 153
SER A 132
None
1.27A 3iltB-5d6gA:
undetectable
3iltE-5d6gA:
undetectable
3iltB-5d6gA:
25.44
3iltE-5d6gA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)
5d6g 50S RIBOSOMAL
PROTEIN L10

(Methanocaldococc
us
jannaschii)
5 / 10 ILE A 153
SER A 132
PRO A 137
MET A 135
LEU A 141
None
1.30A 3iltB-5d6gA:
undetectable
3iltE-5d6gA:
undetectable
3iltB-5d6gA:
25.44
3iltE-5d6gA:
25.44