SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
 0.39A 11gsA-5d73A:
31.0		 11gsA-5d73A:
42.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		5 / 7 TYR A   7
PHE A   8
GLY A  12
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
None
 0.37A 11gsB-5d73A:
31.0		 11gsB-5d73A:
42.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 TYR A 106
GLY A 204
TYR A   7
GLY A  12
 None
 0.65A 11gsB-5d73A:
31.0		 11gsB-5d73A:
42.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		6 / 10 TYR A   7
PHE A   8
PRO A   9
TYR A 106
PRO A 201
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
None
None
 0.41A 13gsA-5d73A:
31.0		 13gsA-5d73A:
42.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		5 / 9 PHE A   8
PRO A   9
TYR A 106
PRO A 201
GLY A 204
 GSH  A 301 (-4.9A)
None
None
None
None
 0.41A 13gsB-5d73A:
31.2		 13gsB-5d73A:
42.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 ARG A  11
TYR A   7
GLU A 156
HIS A 161
 None
 1.02A 1nx9A-5d73A:
undetectable		 1nx9A-5d73A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 ARG A  11
TYR A   7
GLU A 156
HIS A 161
 None
 1.02A 1nx9B-5d73A:
undetectable		 1nx9B-5d73A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 ARG A  11
TYR A   7
GLU A 156
HIS A 161
 None
 1.02A 1nx9C-5d73A:
undetectable		 1nx9C-5d73A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 ARG A  11
TYR A   7
GLU A 156
HIS A 161
 None
 1.01A 1nx9D-5d73A:
undetectable		 1nx9D-5d73A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 LEU A 125
PHE A 128
ARG A  95
THR A  99
 None
None
GSH  A 301 (-3.8A)
None
 1.01A 2eikA-5d73A:
undetectable
2eikJ-5d73A:
undetectable		 2eikA-5d73A:
16.63
2eikJ-5d73A:
15.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
 0.49A 2gssA-5d73A:
31.1		 2gssA-5d73A:
42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
 0.48A 2gssB-5d73A:
31.0		 2gssB-5d73A:
42.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		3 / 3 VAL A 153
GLU A 157
GLU A 156
 None
 0.65A 2nv4A-5d73A:
undetectable		 2nv4A-5d73A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 LEU A 125
PHE A 128
ARG A  95
THR A  99
 None
None
GSH  A 301 (-3.8A)
None
 1.04A 2zxwN-5d73A:
undetectable
2zxwW-5d73A:
undetectable		 2zxwN-5d73A:
16.63
2zxwW-5d73A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 LEU A 125
PHE A 128
ARG A  95
THR A  99
 None
None
GSH  A 301 (-3.8A)
None
 1.00A 3ag4N-5d73A:
undetectable
3ag4W-5d73A:
undetectable		 3ag4N-5d73A:
16.63
3ag4W-5d73A:
15.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		6 / 9 TYR A   7
PHE A   8
PRO A   9
GLY A  12
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
None
None
 0.37A 3csjB-5d73A:
30.8		 3csjB-5d73A:
42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
 0.42A 3gssA-5d73A:
30.9		 3gssA-5d73A:
42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
 0.42A 3gssB-5d73A:
30.9		 3gssB-5d73A:
42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 7 TYR A 106
TYR A   7
THR A   6
GLY A  12
 None
 0.74A 3gssB-5d73A:
30.9		 3gssB-5d73A:
42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 TYR A   7
PHE A   8
TRP A  38
GLY A 204
 None
GSH  A 301 (-4.9A)
GSH  A 301 (-4.0A)
None
 0.25A 3hjoA-5d73A:
30.6		 3hjoA-5d73A:
41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 PHE A   8
TRP A  38
ASN A 203
GLY A 204
 GSH  A 301 (-4.9A)
GSH  A 301 (-4.0A)
None
None
 0.36A 3hjoB-5d73A:
30.6		 3hjoB-5d73A:
41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		6 / 10 TYR A   7
PHE A   8
GLY A  12
TRP A  38
ASN A 203
GLY A 204
 None
GSH  A 301 (-4.9A)
None
GSH  A 301 (-4.0A)
None
None
 0.39A 3km6A-5d73A:
30.7		 3km6A-5d73A:
41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		5 / 9 TYR A   7
PHE A   8
TRP A  38
ASN A 203
GLY A 204
 None
GSH  A 301 (-4.9A)
GSH  A 301 (-4.0A)
None
None
 0.40A 3km6B-5d73A:
30.5		 3km6B-5d73A:
41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		6 / 9 TYR A   7
PHE A   8
GLY A  12
TRP A  38
ASN A 203
GLY A 204
 None
GSH  A 301 (-4.9A)
None
GSH  A 301 (-4.0A)
None
None
 0.43A 3kmoA-5d73A:
30.5		 3kmoA-5d73A:
41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		5 / 7 TYR A   7
PHE A   8
TRP A  38
ASN A 203
GLY A 204
 None
GSH  A 301 (-4.9A)
GSH  A 301 (-4.0A)
None
None
 0.46A 3kmoB-5d73A:
30.5		 3kmoB-5d73A:
41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
 0.52A 3n9jA-5d73A:
30.9		 3n9jA-5d73A:
42.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		5 / 8 TYR A   7
PHE A   8
GLY A  12
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
None
 0.52A 3n9jB-5d73A:
30.7		 3n9jB-5d73A:
42.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 8 TYR A 106
GLY A 204
TYR A   7
GLY A  12
 None
 0.72A 3n9jB-5d73A:
30.7		 3n9jB-5d73A:
42.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		5 / 11 LEU A  70
ASP A  55
HIS A  69
LEU A  21
ILE A  26
 None
 1.47A 3o94A-5d73A:
undetectable		 3o94A-5d73A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		3 / 3 VAL A  22
GLY A  25
LYS A  27
 None
 0.42A 4k50I-5d73A:
undetectable		 4k50I-5d73A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 6 PHE A   8
PRO A   9
ARG A  18
ILE A  33
 GSH  A 301 (-4.9A)
None
None
None
 1.39A 5ih0A-5d73A:
undetectable		 5ih0A-5d73A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5d73 GLUTATHIONE
S-TRANSFERASE
(Wuchereria
bancrofti) 		4 / 6 PHE A   8
PRO A   9
THR A   6
ILE A  33
 GSH  A 301 (-4.9A)
None
None
None
 1.30A 5ih0A-5d73A:
undetectable		 5ih0A-5d73A:
20.25