SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5d76 PUTATIVE PHAGE LYSIN
(Streptococcus
phage
phi7917) 		4 / 5 TYR A 237
VAL A 214
ILE A 206
MET A  36
 None
 1.25A 1opjA-5d76A:
undetectable		 1opjA-5d76A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 5d76 PUTATIVE PHAGE LYSIN
(Streptococcus
phage
phi7917) 		5 / 12 MET A  36
LEU A  45
ALA A   7
GLU A  34
THR A  91
 None
 1.14A 3c6gB-5d76A:
undetectable		 3c6gB-5d76A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5d76 PUTATIVE PHAGE LYSIN
(Streptococcus
phage
phi7917) 		4 / 7 TYR A 237
VAL A 214
ILE A 206
MET A  36
 None
 1.17A 3ik3A-5d76A:
undetectable		 3ik3A-5d76A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5d76 PUTATIVE PHAGE LYSIN
(Streptococcus
phage
phi7917) 		4 / 7 TYR A 237
VAL A 214
ILE A 206
MET A  36
 None
 1.16A 3ik3B-5d76A:
undetectable		 3ik3B-5d76A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5d76 PUTATIVE PHAGE LYSIN
(Streptococcus
phage
phi7917) 		4 / 7 ASN A  74
ALA A  73
ALA A  47
ARG A  35
 None
 1.14A 3twpA-5d76A:
undetectable		 3twpA-5d76A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5d76 PUTATIVE PHAGE LYSIN
(Streptococcus
phage
phi7917) 		5 / 9 ALA A  47
GLY A  50
LEU A  45
ASN A  70
ILE A  60
 None
None
None
CL  A 301 (-4.2A)
None
 1.37A 3wdmA-5d76A:
undetectable		 3wdmA-5d76A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5d76 PUTATIVE PHAGE LYSIN
(Streptococcus
phage
phi7917) 		5 / 9 ALA A  47
GLY A  50
LEU A  45
ASN A  70
ILE A  65
 None
None
None
CL  A 301 (-4.2A)
None
 1.37A 3wdmA-5d76A:
undetectable		 3wdmA-5d76A:
23.45