SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 TYR A 224
ARG A  95
GLN A  91
 None
 0.94A 1tw4A-5d79A:
undetectable		 1tw4A-5d79A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 9 THR A 190
LEU A 191
LEU A 355
GLU A 159
LEU A 138
 None
 1.34A 2azqA-5d79A:
undetectable		 2azqA-5d79A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 THR A 164
ILE A 136
VAL A 147
ALA A 168
VAL A 244
 None
 1.28A 2g72B-5d79A:
undetectable		 2g72B-5d79A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLU A 426
THR A 401
LEU A 197
GLY A 186
PHE A 371
 None
 1.42A 3ce6D-5d79A:
undetectable		 3ce6D-5d79A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 10 LEU A  32
ALA A 126
VAL A  93
ILE A 128
ILE A  60
 None
 1.04A 3el5A-5d79A:
undetectable		 3el5A-5d79A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 GLU A 222
TRP A 226
LEU A 507
ASN A 503
 None
 1.38A 3k8mB-5d79A:
undetectable		 3k8mB-5d79A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 GLY A 496
PHE A 403
GLY A 468
PHE A 371
 None
 0.77A 3ko0O-5d79A:
undetectable
3ko0Q-5d79A:
undetectable		 3ko0O-5d79A:
12.05
3ko0Q-5d79A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 9 GLY A 180
GLY A 181
VAL A 471
ASN A 472
ILE A 239
 FAD  A 603 (-3.6A)
FAD  A 603 (-3.2A)
None
FAD  A 603 (-3.7A)
FAD  A 603 (-3.8A)
 1.43A 3owxA-5d79A:
undetectable		 3owxA-5d79A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 9 PHE A 417
PHE A 403
ASN A 472
THR A 401
PHE A 371
 None
None
FAD  A 603 (-3.7A)
None
None
 1.30A 3t3rB-5d79A:
undetectable		 3t3rB-5d79A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 9 PHE A 417
PHE A 403
ASN A 472
THR A 401
PHE A 371
 None
None
FAD  A 603 (-3.7A)
None
None
 1.28A 3t3rC-5d79A:
undetectable		 3t3rC-5d79A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 TYR A 470
GLY A 232
TYR A 113
ALA A 227
LEU A 507
 FAD  A 603 (-4.5A)
None
FAD  A 603 (-4.9A)
None
None
 1.16A 3vywB-5d79A:
undetectable		 3vywB-5d79A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 6 SER A 339
THR A 254
ILE A 253
PHE A 343
 None
 1.07A 4acbC-5d79A:
undetectable		 4acbC-5d79A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 LEU A 341
GLY A 154
GLY A 178
LEU A 352
GLY A 161
 None
None
FAD  A 603 (-3.4A)
None
None
 1.08A 4blvA-5d79A:
undetectable		 4blvA-5d79A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 VAL A 104
THR A 517
ILE A  94
SER A 211
PHE A 519
 None
 1.35A 4c49D-5d79A:
undetectable		 4c49D-5d79A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_A_SAMA401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 TYR A 461
TYR A 455
GLU A 383
ALA A 380
PRO A 460
 None
 1.48A 4dmgA-5d79A:
undetectable		 4dmgA-5d79A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 SER A 135
GLN A 148
ILE A 128
VAL A  93
 None
PO4  A 602 (-3.8A)
None
None
 1.02A 4dx7B-5d79A:
undetectable		 4dx7B-5d79A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LYS A 257
THR A 303
ILE A 173
 None
 0.89A 4e0fB-5d79A:
undetectable		 4e0fB-5d79A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 5 ILE A 399
THR A 401
HIS A 174
TYR A 113
 None
None
FAD  A 603 ( 3.5A)
FAD  A 603 (-4.9A)
 1.22A 4oltB-5d79A:
undetectable		 4oltB-5d79A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ILE A 399
THR A 401
HIS A 174
TYR A 113
 None
None
FAD  A 603 ( 3.5A)
FAD  A 603 (-4.9A)
 1.22A 4qwpA-5d79A:
undetectable		 4qwpA-5d79A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 11 LEU A  32
ALA A 126
VAL A  93
ILE A 128
ILE A  60
 None
 0.98A 4rvjA-5d79A:
undetectable		 4rvjA-5d79A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 11 LEU A  32
ALA A 126
VAL A  93
ILE A 128
ILE A  60
 None
 0.97A 4rvjC-5d79A:
undetectable		 4rvjC-5d79A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ASP A  54
ARG A 107
ARG A 131
 None
 0.88A 4x5iA-5d79A:
undetectable		 4x5iA-5d79A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ASP A 369
TYR A 455
ASP A 370
ASP A 475
 None
 1.01A 4xjeA-5d79A:
undetectable		 4xjeA-5d79A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 PRO A  78
SER A 117
GLY A 115
ASP A  62
LEU A  61
 None
FAD  A 603 (-2.5A)
None
None
None
 1.34A 5eeiA-5d79A:
undetectable		 5eeiA-5d79A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 PRO A  78
SER A 117
GLY A 115
ASP A  62
LEU A  61
 None
FAD  A 603 (-2.5A)
None
None
None
 1.33A 5eeiB-5d79A:
undetectable		 5eeiB-5d79A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 4 LEU A 314
LEU A 326
GLY A 330
GLU A 329
 None
 1.16A 5hhjA-5d79A:
undetectable		 5hhjA-5d79A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 7 GLY A 181
GLY A 185
PHE A 417
GLY A 186
LEU A 197
 FAD  A 603 (-3.2A)
None
None
None
None
 1.26A 5izjB-5d79A:
undetectable		 5izjB-5d79A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ARG A 143
LYS A 245
ARG A 420
 None
 1.37A 6c06D-5d79A:
undetectable		 6c06D-5d79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 5 THR A 152
ARG A 358
THR A 106
ASP A 522
 None
None
FAD  A 603 (-4.4A)
None
 1.00A 6ecxA-5d79A:
undetectable		 6ecxA-5d79A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 LEU A 400
ILE A 398
VAL A 430
ASP A 369
ILE A 427
 None
 0.86A 6emuC-5d79A:
undetectable		 6emuC-5d79A:
17.45