SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d7e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 5d7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		5 / 11 ILE A  36
PHE A  51
ILE A 120
PRO A 121
ILE A   9
 None
 1.06A 1dyrA-5d7eA:
undetectable		 1dyrA-5d7eA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5d7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		5 / 11 ILE A   9
ILE A 120
ILE A 101
GLU A  98
VAL A  54
 None
 0.90A 3tmzA-5d7eA:
undetectable		 3tmzA-5d7eA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5d7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  51
ILE A 101
THR A 137
LEU A 127
LEU A  92
 None
 1.22A 4qynB-5d7eA:
1.3		 4qynB-5d7eA:
20.81