SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 5d7l MAV36 TCR ALPHA
CHAIN
(Homo
sapiens) 		4 / 7 LYS D  37
LEU D  46
GLU D  39
LEU D  21
 None
 1.06A 1sn0B-5d7lD:
undetectable
1sn0D-5d7lD:
undetectable		 1sn0B-5d7lD:
19.29
1sn0D-5d7lD:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 5d7l MAV36 TCR ALPHA
CHAIN
(Homo
sapiens) 		4 / 4 PRO D  43
THR D  44
GLY D  82
THR D  81
 None
 1.10A 3ib1A-5d7lD:
undetectable		 3ib1A-5d7lD:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5d7l MAV36 TCR ALPHA
CHAIN
(Homo
sapiens) 		4 / 5 ASP D  83
THR D  81
GLU D  39
LYS D  37
 None
 1.28A 4a3pA-5d7lD:
undetectable		 4a3pA-5d7lD:
22.63