SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 SER A 379
LEU A  13
TYR A   6
GLY A 361
 SER  A 379 ( 0.0A)
LEU  A  13 ( 0.6A)
TYR  A   6 ( 1.3A)
GLY  A 361 (-0.0A)
 1.48A 1liiA-5d7wA:
undetectable		 1liiA-5d7wA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.28A 1os2A-5d7wA:
14.6		 1os2A-5d7wA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.30A 1os2D-5d7wA:
14.7		 1os2D-5d7wA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 12 GLU A 329
ASN A 347
GLY A 363
SER A 311
ILE A 328
 GLU  A 329 (-0.6A)
ASN  A 347 (-0.6A)
GLY  A 363 (-0.0A)
SER  A 311 ( 0.0A)
ILE  A 328 ( 0.7A)
 1.12A 1q8jB-5d7wA:
undetectable		 1q8jB-5d7wA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 10 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 THR  A 173 ( 0.8A)
HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.49A 1r55A-5d7wA:
6.8		 1r55A-5d7wA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 THR A 272
GLY A 333
ASP A 338
ALA A 299
 THR  A 272 ( 0.8A)
GLY  A 333 ( 0.0A)
ASP  A 338 (-0.5A)
ALA  A 299 ( 0.0A)
 1.25A 1sg9A-5d7wA:
undetectable		 1sg9A-5d7wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 THR A 272
GLY A 334
ASP A 338
ALA A 299
 THR  A 272 ( 0.8A)
GLY  A 334 (-0.0A)
ASP  A 338 (-0.5A)
ALA  A 299 ( 0.0A)
 0.90A 1sg9A-5d7wA:
undetectable		 1sg9A-5d7wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.37A 1uttA-5d7wA:
14.4		 1uttA-5d7wA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.29A 1utzA-5d7wA:
14.3		 1utzA-5d7wA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.31A 1utzB-5d7wA:
14.3		 1utzB-5d7wA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 1v54A-5d7wA:
undetectable		 1v54A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.89A 1v54C-5d7wA:
undetectable
1v54J-5d7wA:
undetectable		 1v54C-5d7wA:
19.92
1v54J-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 1v54N-5d7wA:
undetectable		 1v54N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 1v55A-5d7wA:
undetectable		 1v55A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.95A 1v55C-5d7wA:
undetectable
1v55J-5d7wA:
undetectable		 1v55C-5d7wA:
19.92
1v55J-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 1v55N-5d7wA:
undetectable		 1v55N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 6 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.30A 1y93A-5d7wA:
14.1		 1y93A-5d7wA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 12 GLY A   5
PHE A 359
ALA A   3
ALA A   8
ASP A  11
 GLY  A   5 ( 0.0A)
PHE  A 359 ( 1.3A)
ALA  A   3 ( 0.0A)
ALA  A   8 ( 0.0A)
ASP  A  11 ( 0.5A)
 1.29A 2avdA-5d7wA:
undetectable		 2avdA-5d7wA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.73A 2dyrA-5d7wA:
undetectable		 2dyrA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.89A 2dyrC-5d7wA:
undetectable
2dyrJ-5d7wA:
undetectable		 2dyrC-5d7wA:
19.92
2dyrJ-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 2dyrN-5d7wA:
undetectable		 2dyrN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 2dysA-5d7wA:
undetectable		 2dysA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.87A 2dysP-5d7wA:
undetectable
2dysW-5d7wA:
undetectable		 2dysP-5d7wA:
19.92
2dysW-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 2eijA-5d7wA:
undetectable		 2eijA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.90A 2eijC-5d7wA:
undetectable
2eijJ-5d7wA:
undetectable		 2eijC-5d7wA:
19.92
2eijJ-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 2eijN-5d7wA:
undetectable		 2eijN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.73A 2eikA-5d7wA:
undetectable		 2eikA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 2eikN-5d7wA:
undetectable		 2eikN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 2eilA-5d7wA:
undetectable		 2eilA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.86A 2eilC-5d7wA:
undetectable
2eilJ-5d7wA:
undetectable		 2eilC-5d7wA:
19.92
2eilJ-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 2eilN-5d7wA:
0.2		 2eilN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 2eimA-5d7wA:
undetectable		 2eimA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.73A 2eimN-5d7wA:
undetectable		 2eimN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.91A 2eimP-5d7wA:
undetectable
2eimW-5d7wA:
undetectable		 2eimP-5d7wA:
19.92
2eimW-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.71A 2einA-5d7wA:
undetectable		 2einA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.71A 2einN-5d7wA:
undetectable		 2einN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.31A 2hu6A-5d7wA:
14.2		 2hu6A-5d7wA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 VAL A 445
VAL A 457
PHE A 407
ALA A 380
 VAL  A 445 ( 0.6A)
VAL  A 457 ( 0.6A)
PHE  A 407 ( 1.3A)
ALA  A 380 ( 0.0A)
 1.16A 2ij7C-5d7wA:
undetectable		 2ij7C-5d7wA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 9 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 THR  A 173 ( 0.8A)
HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.40A 2jihA-5d7wA:
7.0		 2jihA-5d7wA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 8 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 THR  A 173 ( 0.8A)
HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.37A 2jihB-5d7wA:
6.8		 2jihB-5d7wA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 THR A 103
PHE A 104
THR A 105
LYS A  90
 THR  A 103 ( 0.8A)
PHE  A 104 ( 1.3A)
THR  A 105 ( 0.8A)
LYS  A  90 ( 0.0A)
 1.02A 2kotA-5d7wA:
undetectable		 2kotA-5d7wA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 TYR A 297
GLY A 334
PHE A 294
 TYR  A 297 ( 1.3A)
GLY  A 334 (-0.0A)
PHE  A 294 ( 1.3A)
 0.67A 2m2pB-5d7wA:
undetectable		 2m2pB-5d7wA:
4.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 6 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.18A 2ow9A-5d7wA:
14.6		 2ow9A-5d7wA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.25A 2ow9B-5d7wA:
14.4		 2ow9B-5d7wA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.23A 2ozrC-5d7wA:
14.6		 2ozrC-5d7wA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.26A 2ozrD-5d7wA:
14.7		 2ozrD-5d7wA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.39A 2ozrE-5d7wA:
14.4		 2ozrE-5d7wA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 176
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.28A 2ozrF-5d7wA:
14.6		 2ozrF-5d7wA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 2y69A-5d7wA:
undetectable		 2y69A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.77A 2y69N-5d7wA:
undetectable		 2y69N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 ALA A 240
TRP A  96
GLY A  36
ILE A  39
 ALA  A 240 ( 0.0A)
TRP  A  96 ( 0.5A)
GLY  A  36 ( 0.0A)
ILE  A  39 ( 0.7A)
 0.90A 2zm9A-5d7wA:
undetectable		 2zm9A-5d7wA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 2zxwN-5d7wA:
undetectable		 2zxwN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 3abkN-5d7wA:
undetectable		 3abkN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 3ablA-5d7wA:
undetectable		 3ablA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.79A 3ablN-5d7wA:
undetectable		 3ablN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 3abmA-5d7wA:
undetectable		 3abmA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 3ag1A-5d7wA:
undetectable		 3ag1A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 3asnN-5d7wA:
undetectable		 3asnN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.99A 3asnP-5d7wA:
undetectable
3asnW-5d7wA:
undetectable		 3asnP-5d7wA:
19.92
3asnW-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 3asoN-5d7wA:
undetectable		 3asoN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.99A 3asoP-5d7wA:
undetectable
3asoW-5d7wA:
undetectable		 3asoP-5d7wA:
19.92
3asoW-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 LEU A 270
SER A 271
ALA A 233
ALA A 232
 LEU  A 270 ( 0.5A)
SER  A 271 ( 0.0A)
ALA  A 233 ( 0.0A)
ALA  A 232 (-0.0A)
 0.82A 3ax9B-5d7wA:
undetectable		 3ax9B-5d7wA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.71A 3bvdA-5d7wA:
undetectable		 3bvdA-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 3dtuA-5d7wA:
undetectable		 3dtuA-5d7wA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 3dtuC-5d7wA:
undetectable		 3dtuC-5d7wA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 9 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 THR  A 173 ( 0.8A)
HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.32A 3hy7A-5d7wA:
7.7		 3hy7A-5d7wA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 9 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 THR  A 173 ( 0.8A)
HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.33A 3hy7B-5d7wA:
7.6		 3hy7B-5d7wA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.28A 3kecA-5d7wA:
14.6		 3kecA-5d7wA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.30A 3likA-5d7wA:
14.3		 3likA-5d7wA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.31A 3lilA-5d7wA:
14.3		 3lilA-5d7wA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.34A 3ljgA-5d7wA:
14.3		 3ljgA-5d7wA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.31A 3lkaA-5d7wA:
14.2		 3lkaA-5d7wA:
26.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 3s33A-5d7wA:
undetectable		 3s33A-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 3s38A-5d7wA:
undetectable		 3s38A-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.77A 3s39A-5d7wA:
undetectable		 3s39A-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 3s3aA-5d7wA:
undetectable		 3s3aA-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.79A 3s3bA-5d7wA:
undetectable		 3s3bA-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.78A 3s3cA-5d7wA:
undetectable		 3s3cA-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 3s3dA-5d7wA:
undetectable		 3s3dA-5d7wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 ASP A 168
GLU A 167
GLY A 170
TYR A 230
 ASP  A 168 (-0.6A)
GLU  A 167 ( 0.6A)
GLY  A 170 ( 0.0A)
TYR  A 230 (-1.3A)
 1.21A 3w9tB-5d7wA:
undetectable		 3w9tB-5d7wA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 GLU A 167
GLY A 170
TYR A 230
GLN A 172
 GLU  A 167 ( 0.6A)
GLY  A 170 ( 0.0A)
TYR  A 230 (-1.3A)
GLN  A 172 ( 0.6A)
 1.46A 3w9tB-5d7wA:
undetectable		 3w9tB-5d7wA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 ASP A 168
GLU A 167
GLY A 170
TYR A 230
 ASP  A 168 (-0.6A)
GLU  A 167 ( 0.6A)
GLY  A 170 ( 0.0A)
TYR  A 230 (-1.3A)
 1.19A 3w9tE-5d7wA:
undetectable		 3w9tE-5d7wA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 3wg7A-5d7wA:
undetectable		 3wg7A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 3wg7N-5d7wA:
undetectable		 3wg7N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 3x2qA-5d7wA:
undetectable		 3x2qA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.71A 3x2qN-5d7wA:
undetectable		 3x2qN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 6 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.25A 4a7bA-5d7wA:
14.6		 4a7bA-5d7wA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 ASN A 226
ARG A 209
ASP A 238
LEU A 235
 ASN  A 226 ( 0.6A)
ARG  A 209 ( 0.6A)
ASP  A 238 ( 0.5A)
LEU  A 235 ( 0.6A)
 0.99A 4k0bA-5d7wA:
undetectable		 4k0bA-5d7wA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 8 ASN A 226
ARG A 209
ASP A 238
LEU A 235
 ASN  A 226 ( 0.6A)
ARG  A 209 ( 0.6A)
ASP  A 238 ( 0.5A)
LEU  A 235 ( 0.6A)
 1.07A 4l7iA-5d7wA:
undetectable		 4l7iA-5d7wA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 TRP A  46
GLN A  54
THR A  45
 TRP  A  46 ( 0.5A)
GLN  A  54 ( 0.6A)
THR  A  45 ( 0.8A)
 0.87A 4m2xA-5d7wA:
undetectable		 4m2xA-5d7wA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 12 LEU A 184
ILE A 242
ILE A 239
GLY A  36
ALA A  35
 LEU  A 184 ( 0.5A)
ILE  A 242 ( 0.4A)
ILE  A 239 ( 0.7A)
GLY  A  36 ( 0.0A)
ALA  A  35 ( 0.0A)
 1.08A 4nkvA-5d7wA:
undetectable		 4nkvA-5d7wA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 12 GLY A 333
GLY A 370
ASP A 394
ILE A 392
ASP A 356
 GLY  A 333 ( 0.0A)
GLY  A 370 (-0.0A)
ASP  A 394 ( 0.6A)
ILE  A 392 ( 0.7A)
ASP  A 356 ( 0.6A)
 1.25A 4rtsA-5d7wA:
undetectable		 4rtsA-5d7wA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 5b1aA-5d7wA:
undetectable		 5b1aA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 5b1aN-5d7wA:
undetectable		 5b1aN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 5b1bA-5d7wA:
undetectable		 5b1bA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 5b1bN-5d7wA:
undetectable		 5b1bN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 5b3sN-5d7wA:
undetectable		 5b3sN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		5 / 12 GLY A  36
ALA A  35
SER A 215
TYR A 190
GLU A  42
 GLY  A  36 ( 0.0A)
ALA  A  35 ( 0.0A)
SER  A 215 ( 0.0A)
TYR  A 190 ( 1.3A)
GLU  A  42 ( 0.6A)
 1.31A 5cprB-5d7wA:
undetectable		 5cprB-5d7wA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 ILE A 303
PHE A 281
GLY A 260
THR A 272
 ILE  A 303 ( 0.7A)
PHE  A 281 ( 1.3A)
GLY  A 260 ( 0.0A)
THR  A 272 ( 0.8A)
 1.03A 5esmA-5d7wA:
undetectable		 5esmA-5d7wA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.73A 5iy5A-5d7wA:
undetectable		 5iy5A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 5iy5N-5d7wA:
undetectable		 5iy5N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 6 SER A 309
GLY A 342
ASN A 343
ILE A 303
 SER  A 309 ( 0.0A)
GLY  A 342 ( 0.0A)
ASN  A 343 (-0.6A)
ILE  A 303 ( 0.7A)
 0.86A 5j4nA-5d7wA:
undetectable		 5j4nA-5d7wA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.31A 5n5jA-5d7wA:
14.2		 5n5jA-5d7wA:
26.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 HIS  A 176 (-1.0A)
GLU  A 177 ( 0.6A)
HIS  A 180 (-1.0A)
HIS  A 186 (-1.0A)
 0.27A 5n5kA-5d7wA:
13.8		 5n5kA-5d7wA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 5w97a-5d7wA:
undetectable		 5w97a-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 6 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.93A 5w97C-5d7wA:
undetectable
5w97J-5d7wA:
undetectable		 5w97C-5d7wA:
19.92
5w97J-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.71A 5x19N-5d7wA:
undetectable		 5x19N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 6 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.91A 5x19P-5d7wA:
undetectable		 5x19P-5d7wA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.70A 5x1bA-5d7wA:
undetectable		 5x1bA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.68A 5x1bN-5d7wA:
undetectable		 5x1bN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.73A 5x1fA-5d7wA:
undetectable		 5x1fA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.66A 5x1fN-5d7wA:
undetectable		 5x1fN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 7 LYS A  57
LEU A  58
PHE A  60
LEU A 182
 LYS  A  57 ( 0.0A)
LEU  A  58 ( 0.6A)
PHE  A  60 ( 1.3A)
LEU  A 182 ( 0.6A)
 0.90A 5x1fP-5d7wA:
undetectable
5x1fW-5d7wA:
undetectable		 5x1fP-5d7wA:
19.92
5x1fW-5d7wA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 5xdqA-5d7wA:
undetectable		 5xdqA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 5xdqN-5d7wA:
undetectable		 5xdqN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.73A 5xdxA-5d7wA:
undetectable		 5xdxA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 5xdxN-5d7wA:
undetectable		 5xdxN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		4 / 4 VAL A 357
LEU A 358
LEU A 349
ASP A 365
 VAL  A 357 ( 0.6A)
LEU  A 358 ( 0.5A)
LEU  A 349 ( 0.6A)
ASP  A 365 ( 0.5A)
 1.05A 5xv7A-5d7wA:
undetectable		 5xv7A-5d7wA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.77A 5z84A-5d7wA:
undetectable		 5z84A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 5z84N-5d7wA:
undetectable		 5z84N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.77A 5z85A-5d7wA:
undetectable		 5z85A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 5z85N-5d7wA:
undetectable		 5z85N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 5z86A-5d7wA:
undetectable		 5z86A-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 5z86N-5d7wA:
undetectable		 5z86N-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 5zcoA-5d7wA:
undetectable		 5zcoA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 5zcoN-5d7wA:
undetectable		 5zcoN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 5zcpA-5d7wA:
undetectable		 5zcpA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 5zcpN-5d7wA:
undetectable		 5zcpN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 5zcqA-5d7wA:
undetectable		 5zcqA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 5zcqN-5d7wA:
undetectable		 5zcqN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.73A 6hu9a-5d7wA:
undetectable		 6hu9a-5d7wA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.74A 6hu9m-5d7wA:
undetectable		 6hu9m-5d7wA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.76A 6nknA-5d7wA:
undetectable		 6nknA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 6nknN-5d7wA:
undetectable		 6nknN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.71A 6nmfA-5d7wA:
undetectable		 6nmfA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.72A 6nmfN-5d7wA:
undetectable		 6nmfN-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 6nmpA-5d7wA:
undetectable		 6nmpA-5d7wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5d7w SERRALYSIN
(Serratia
marcescens) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 HIS  A 186 (-1.0A)
HIS  A 180 (-1.0A)
HIS  A 176 (-1.0A)
 0.75A 6nmpN-5d7wA:
undetectable		 6nmpN-5d7wA:
21.94