SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5d7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		3 / 3 GLU A 288
ILE A 262
ARG A 254
 None
 0.69A 1cd2A-5d7zA:
undetectable		 1cd2A-5d7zA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 12 ALA A 108
ILE A 111
ALA A 100
LEU A 155
PHE A  46
 None
 1.27A 1udtA-5d7zA:
undetectable		 1udtA-5d7zA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 5 ALA A  64
TYR A  42
ILE A  39
ASP A 137
 None
 1.19A 1upfA-5d7zA:
undetectable		 1upfA-5d7zA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 5 ALA A 194
TYR A 172
ILE A 169
ASP A 271
 None
 1.13A 1upfA-5d7zA:
undetectable		 1upfA-5d7zA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 5 ALA A  64
TYR A  42
ILE A  39
ASP A 137
 None
 1.08A 1upfC-5d7zA:
undetectable		 1upfC-5d7zA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 5 ALA A 194
TYR A 172
ILE A 169
ASP A 271
 None
 1.06A 1upfC-5d7zA:
undetectable		 1upfC-5d7zA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		3 / 3 LYS A 265
TYR A 235
PRO A 258
 None
 1.32A 2j9cC-5d7zA:
undetectable		 2j9cC-5d7zA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 6 PHE A 143
LEU A  66
VAL A  77
ASP A 137
 None
 1.09A 2zawA-5d7zA:
undetectable		 2zawA-5d7zA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 12 PHE A  94
GLY A  91
ASN A 222
TYR A 224
PHE A  97
 None
 1.41A 3a27A-5d7zA:
undetectable		 3a27A-5d7zA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_A_CLMA221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 9 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.43A 3u9fA-5d7zA:
0.0		 3u9fA-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 12 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.44A 3u9fD-5d7zA:
undetectable
3u9fE-5d7zA:
undetectable		 3u9fD-5d7zA:
21.07
3u9fE-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 10 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.46A 3u9fE-5d7zA:
undetectable		 3u9fE-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_F_CLMF221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 10 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.44A 3u9fD-5d7zA:
undetectable
3u9fF-5d7zA:
undetectable		 3u9fD-5d7zA:
21.07
3u9fF-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 12 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.43A 3u9fG-5d7zA:
undetectable
3u9fH-5d7zA:
undetectable		 3u9fG-5d7zA:
21.07
3u9fH-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 10 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.44A 3u9fI-5d7zA:
undetectable		 3u9fI-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 10 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.45A 3u9fK-5d7zA:
undetectable		 3u9fK-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 11 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.47A 3u9fN-5d7zA:
undetectable
3u9fO-5d7zA:
undetectable		 3u9fN-5d7zA:
21.07
3u9fO-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 11 THR A 231
TYR A 198
SER A 237
PHE A 171
VAL A 241
 None
 1.45A 3u9fM-5d7zA:
undetectable
3u9fO-5d7zA:
undetectable		 3u9fM-5d7zA:
21.07
3u9fO-5d7zA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		5 / 12 GLN A 157
ALA A  98
VAL A 104
LEU A 107
ILE A 118
 None
 1.07A 4g1bA-5d7zA:
undetectable		 4g1bA-5d7zA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 8 LYS A 183
LEU A 180
THR A 192
LEU A 196
 None
 0.90A 4ik6B-5d7zA:
undetectable		 4ik6B-5d7zA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 6 PHE A 143
LEU A  66
VAL A  77
ASP A 137
 None
 1.08A 4kkyX-5d7zA:
undetectable		 4kkyX-5d7zA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 7 PHE A 143
LEU A  66
VAL A  77
ASP A 137
 None
 1.04A 4l4gA-5d7zA:
undetectable		 4l4gA-5d7zA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 7 ILE A  90
PHE A 143
THR A  38
LEU A  79
 None
 0.92A 4ze3A-5d7zA:
undetectable		 4ze3A-5d7zA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 5 PRO A 122
ALA A 133
ALA A 108
ILE A 118
 None
 0.74A 5jncD-5d7zA:
undetectable		 5jncD-5d7zA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 5 PRO A 256
ALA A 267
ALA A 238
ILE A 252
 None
 0.79A 5jncD-5d7zA:
undetectable		 5jncD-5d7zA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5d7z LACTOYLGLUTATHIONE
LYASE
(Zea
mays) 		4 / 7 ASP A 273
ASP A 271
ARG A 167
TYR A 211
 None
 1.49A 6g31G-5d7zA:
undetectable		 6g31G-5d7zA:
15.69